[MG] (WcaG) COG0451 Nucleoside-diphosphate-sugar epimerases 8 genomes BUD1010 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0128 rrnAC2305 HVO_0511 Hbo1042 Hmu0083 - hla0406 NP0308A HQ1135A

Pairwise sequence scores
Consensus score	2031	VNG0128	HQ1135A	hla0406	HVO_0511	Hbo1042	NP0308A	rrnAC2305	Hmu0083
1565	VNG0128	2034	1360	1394	1384	1353	1397	1372	1415
1521	HQ1135A	1360	2051	1355	1367	1456	1208	1330	1320
1666	hla0406	1394	1355	2363	1570	1525	1345	1380	1317
1606	HVO_0511	1384	1367	1570	2075	1604	1282	1418	1340
1653	Hbo1042	1353	1456	1525	1604	1992	1234	1423	1371
1521	NP0308A	1397	1208	1345	1282	1234	2040	1509	1526
1689	rrnAC2305	1372	1330	1380	1418	1423	1509	2033	1704
1668	Hmu0083	1415	1320	1317	1340	1371	1526	1704	2015

302 symbols
consensus       ----MDEPVLLTGAGGRVGQAILRGLGDDYEWRLLDREPPPAEP-P--V-DHDYYVADVT
#oth            1111.121......2.2..3..121221313.112112.254223123143423313.11
VNG0128         MTTR::::::::::S::::::::G:I::::T:::F:::::TDD::-::-:::EFV:::I:
HQ1135A         ::::::::::::::S::::E::::HA:E:FA:::F::::V:RDRR:SR:AAD:VFIS:::
hla0406         :::::::::::::::::::::::::I:::::::::::::L::AKV:DG:T:A:Q::::I:
HVO_0511        ::::::Q::::::::::::::::GHI::A:D::::::::LSD:KI:DS:DSTEV::::::
Hbo1042         ::::::::::::::::::::::::H:::RF:::::::::LG::KR:DG:GEE:V::T:I:
NP0308A         :::::::T::::::K:S::T::RE::A:E:D::Y:FHN:::FD::-::-:::P:L:G::S
rrnAC2305       ::::::D:::::::::A::A:::E::E:A:::K:MFHS::AE:::-::-:::E:L:G::S
Hmu0083         :::::N::::::::::A::E:::G::E:::::K:MFHS::VE:::-::-:::::V:G::S

consensus       DEEAVRAAMEGVGAVIHLAGDPRPEAPWDSVLRNNIDGTQKMYEAAVDAGVEKFVFASSN
#oth            2342132.42113.11.......22...3...2...2..34332..2321.21221....
VNG0128         ::T:::E:ASD:::IV::::::::::::E::::::::::RTVLD::LA:::DRV::::::
HQ1135A         :TN:LIN:I::CK:::::::::::::::K:::E:::N:::AV:::::N:D:DR:I:::::
hla0406         NAD:::E::::::::::::::::KT:::::::::::::::VVMR:::::::K::A:::::
HVO_0511        ::T:::N::D::H:::::::::::::::::::::::::::Q:FD::::V:::::A:::::
Hbo1042         :::::E:::D::Y::::::::::::::::::::::::::HTIF::::::::::IA:::::
NP0308A         :::L:AE:C:D::::V:::::::RD:::::::E:::H::KVL:D::IE::::::::::::
rrnAC2305       S:GD:A:::D::::::::::::::::::::::E:::::::::::::::E:::::::::::
Hmu0083         :D:D::::V:::::I:::::::::D:::N:::A:::::::::::::::E:::R::Y::::

consensus       HAVGAYETDERTPDLYRPDDDFRLDGTELPRPGNLYGVSKATGEVLGRYYHDEHGISVCN
#oth            ....31.131.1.21..22141....2.2.1.1.1..1...1..31..1.1.21123122
VNG0128         ::::H::-TD:K:::::S::::::::::R::::::::::::A::T::::::::::LTFAA
HQ1135A         ::::S:::N::::AM::S::TY::::R:::::S:::::::::::II::::::N:::A:A:
hla0406         ::::G:::E:::::::::::GY:::::::::::::::::::A::S:::F::::::M::VC
HVO_0511        ::::::::TD::::M:::HHE:::::::::::S::::::::A::T:::::::H:D:::V:
Hbo1042         :::::::::::::EM:::E:G:::::::::H:S:::::::::::::::::Y:H:DL::V:
NP0308A         ::::HF:-TD:K:E:::T::::::::::F:::::H::I:::::::I:::::::Y::D:::
rrnAC2305       ::::SF:::::::EM:::::QY:::::::::::::::::::::::::::::::::L::::
Hmu0083         :::::::-:::K:::::TH:::::::S:F:::::::::::::::II:::::::Y::D:::

consensus       VRIGNLTKGHPPIDYERGQAMWLSYRDCAHLFDRCLQADYDYEIVYGISDNDRKYYSIER
#oth            1......42...21..........2...1.1221124.1.21.11....1...1...121
VNG0128         :::::::A::::::::::::::::P::::::I::::S::::::V:::::::::::::LA:
HQ1135A         :::::::E::::::::::::::::::::::::S::ID:E:EF::I:::::::::::::AH
hla0406         ::::::::D:::RE::::::::::H:::G:::::::::::G::::::::N:::R::::::
HVO_0511        :::::::QH:::KE::::::::::::::G:::EC:IE:::::::::::::::::::::D:
Hbo1042         :::::::E::::::::::::::::::::::::E::VL:::::::::::::::::::::::
NP0308A         I:::::::::::KE:::::::::::::::::H::A::::::F:::::::::::::::L::
rrnAC2305       I::::::R::::::::::::::::::::::IH:CA:::::E:::::::::::::::::::
Hmu0083         ::::::::::::::::::::::::::::::IHE:A:L::::F::::::::::::::::::

consensus       AKEVLGYDPQDNSA--EFDGEERDAA----------------------------------
#oth            .122...2.4....2222214234563521111111111111111111111111111111
VNG0128         ::DA:::E:R:::::::W::D:KLSGGS::::::::::::::::::::::::::::::::
HQ1135A         :::T:::N:::::::::WQ:K::IVKKGE:::::::::::::::::::::::::::::::
hla0406         :R:::::::A::::DYT:E:KPK:ETGDENDNPTADGGETRFDDPPAEPNFPSDPDTPTD
HVO_0511        :RA:::::::::::EFT:E::PL:E:::::::::::::::::::::::::::::::::::
Hbo1042         :R:::::::V:::::::HED------::::::::::::::::::::::::::::::::::
NP0308A         ::D::::E:K::::DYH:::TPK:D:::::::::::::::::::::::::::::::::::
rrnAC2305       ::D:::::::::::::H::::::V:EPEP:::::::::::::::::::::::::::::::
Hmu0083         :::::::E::::::::H::::::V:DPT::::::::::::::::::::::::::::::::

consensus       --
#oth            11
VNG0128         ::
HQ1135A         ::
hla0406         GA
HVO_0511        ::
Hbo1042         ::
NP0308A         ::
rrnAC2305       ::
Hmu0083         ::