8 genomes BUD1018 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0151 pNG7058 HVO_1244 Hbo0302 - Hut0618 hla1626 NP1606A NP3914A HQ2374A

Pairwise sequence scores
Consensus score	1316	NP3914A	Hut0618	hla1626	NP1606A	HQ2374A	HVO_1244	Hbo0302	VNG0151	pNG7058
717	NP3914A	1426	380	465	471	459	530	507	255	357
650	Hut0618	380	1300	382	456	475	574	551	283	444
671	hla1626	465	382	1463	550	412	518	494	147	353
684	NP1606A	471	456	550	1324	452	460	568	190	410
754	HQ2374A	459	475	412	452	1546	605	596	339	564
912	HVO_1244	530	574	518	460	605	1489	849	336	528
887	Hbo0302	507	551	494	568	596	849	1327	314	572
445	VNG0151	255	283	147	190	339	336	314	704	416
691	pNG7058	357	444	353	410	564	528	572	416	1277

212 symbols
consensus       MRRRALLAGLGGAAVLGGAGAV------------------------ASDADGDGSGGL--
#oth            231142253532434423345434234133434222211111354345656465646512
NP3914A         :Q::TV:G::A:::T:AVG:WA:ARRGPTAGDS:::::::::VGNA:G:E:::::::V::
Hut0618         ::::E::::V:::::V:AG:YL::::::::::::::::::::::::---:LTA:EERI:D
hla1626         V:::D:::::ASVGA:::::::ATGRVPDAIGG:::::::::DELGG:E::::RAEPI:E
NP1606A         ::::DV:I:A:SL:::::GA:::::::::::::::::::::::::::F::V:SD::TYVD
HQ2374A         :K:::V:KAT::IVLT::SVMILQRGIPTLNPTETQS:::::DTTSE:SEAVNSKTTF::
HVO_1244        V::::::SL:A::G:A:V::CLGDGSAPAEAGDAAETTSDAADPAS:TASS:S:::D:::
Hbo0302         VK::E:I::V:SL::V::::Y::::::::::::::::::::::::::LNGV:L:DD::::
VNG0151         ----------------------::::::::::::::::::::::::------------::
pNG7058         ---------MT:LGLT::SLW:::::::::::::::::::::AQNGL:GIRSQNTDQ:::

consensus       PVQLDTLDAPGSEAGEVRVPAPGRPTVVDLFATWCAPCEAQMEALRAAHAEYGDDVAFVS
#oth            155342433522543443326437222332122117316542441433454423315.2.
NP3914A         :A:IE:I::::::::SL-:LEEEY:L::TF:::::SS:SRE:SD:T:::::V::Q:P:L:
Hut0618         :TVI:LF:TSTTAGA:L:::VN:EV::::::::::Q::KPALD:::TVQ::T-T:I::::
hla1626         ::T:::VE::::RD:::TL:M:D:::F::F:G:::P:::E::P::AE::DRI::E:L:::
NP1606A         ::D:E::::::::::TTT::D:::V:F:E:::K::GI::DM:P::AE:S:AV-EG:Q:::
HQ2374A         :I::S::GVE::TERT::::TA:M:::I:::::::T::Q:::D::STVYSK:N:Q:G:I:
HVO_1244        :LVV::V::Q::S:::::I::E:A:::L::::::::::V::::S::TL:E:F::::::::
Hbo0302         :LTVQ::::::::::KRP:::::K:::L:::::::V::S::::S:T:L:E:F::::::::
VNG0151         --------------------------------------------M::VRGD:-P::S:::
pNG7058         ::RVE::::R::S:::TP::T::TV:::::::::::::DD:L:I:DSIRP::-T::S:I:

consensus       VTNERLGGTLTRADVADWWREHDGAWTVGHDPDSELMAALGANGLPYLAVVDADGEVVWT
#oth            1.2.4414521332245..4321.4.3114.24361345241623.24333.34122425
NP3914A         L:G:VV:RSVS::E::::::::::::SL:L::::QV:NQFSVI:I:SVVL:::::::::S
Hut0618         ::::V:::E:S:D::LA::DAYG:::P:::::EGG:L:S:::ST:::T::::PS:R:::A
hla1626         ::T:DV::AV:EET::N::::N::D:L:AA:VTA::A:R:NVG:Y:SARAI::S:R:R:A
NP1606A         ::::A::T:T::E::IE:::D:::::P:AV:A:LA:TQR:D:T:V::AF:I::ENR:S:Q
HQ2374A         :::::I::::::::IRS::N::::R:S::L::K:K::NI:::Q::::::IT:TT::IR:E
HVO_1244        ::::::::G::MD:IR:::A::::N:::::::::S::R:VR:::::::V:F:::::AT::
Hbo0302         ::::GF:DN::AD::RK::AD:::::::::::E:R::KV:::G:::::::F::::TAT::
VNG0151         :::::V:D::::G:L::::TANG:E::L:V::G:GVL::F:::A::FV:IT:::::I:A:
pNG7058         :::::PSE::::::IGE::NRNG::::::I::G:::L::F::D::::I:I::ER:T:QFG

consensus       HSGLASAETLRAEIDAVL--------------
#oth            32.55343434443432543211111111111
NP3914A         D::HVDTDA:V::AAT:ADNA:::::::::::
Hut0618         ET:VPDP:RVSQA:ADARP:::::::::::::
hla1626         T::THTT:EFVDG:ERA:DR::::::::::::
NP1606A         :R:ASD::EII:Q:R::QG:::::::::::::
HQ2374A         DT:MT::S::QH:L::::SKSEGKSENENENE
HVO_1244        :R::::E:N:::AVED:A::::::::::::::
Hbo0302         :R::::ESN:::Q:T:::::::::::::::::
VNG0151         :::V:::A:::ERL:T:T::::::::::::::
pNG7058         :::::GK::::D:L::LV::::::::::::::