[E] (AroE) COG0169 Shikimate 5-dehydrogenase 8 genomes BUD1031 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0382 rrnAC0707 - Hbo0823 Hmu0930 Hut0135 hla0082 NP0806A HQ1245A

Pairwise sequence scores
Consensus score	1974	HQ1245A	VNG0382	Hut0135	Hmu0930	rrnAC0707	NP0806A	Hbo0823	hla0082
1494	HQ1245A	2046	1315	1300	1277	1258	1395	1440	1414
1542	VNG0382	1315	1963	1302	1352	1306	1244	1399	1452
1576	Hut0135	1300	1302	1954	1539	1561	1438	1351	1374
1619	Hmu0930	1277	1352	1539	2001	1567	1381	1406	1446
1630	rrnAC0707	1258	1306	1561	1567	1986	1452	1372	1454
1556	NP0806A	1395	1244	1438	1381	1452	1965	1441	1472
1607	Hbo0823	1440	1399	1351	1406	1372	1441	2021	1533
1676	hla0082	1414	1452	1374	1446	1454	1472	1533	2053

281 symbols
consensus       --MDVYGLIGNPVGHSLSPPMHEAAYDALGIDARYVTFEPAPDAAAAAIEGAEALGVAGL
#oth            11.111..1....1..1...1.1.1.24212.........3513352.232.51.114.1
HQ1245A         ::::I::::::::E::::::::::::::R:::::::::::TK:TLET::N::N::DI::I
VNG0382         ::::::::::::::::::::L:A::::EC:L::::::::::::D:::::R::G:::::::
Hut0135         ::::::::L::::E:::::::::::::E::::::::::::PV:::RE:V:A::T:::S::
Hmu0930         :::::F::::::::::::::::::::EQ:DM:::::::::DE::::::::S:RT::IT::
rrnAC0707       ::::::::::::::::::::::::G:E:::L:::::::::PA::G:E:::A::T:::D::
NP0806A         :::::::::::::E::V:::::::::E:::L::::::::::SEQLDT:L:::S::::R::
Hbo0823         MS:Q:F:::::::::::::::::::::HC:::::::::::::EDIGT:V:::D:::IT::
hla0082         ::::::::::::::::::::::::G:GT:::::::::::::::D:V:::G::G:::::::

consensus       NVTIPFKQDVLDAVDPDPLAERIGAVNTIDF----TGDT--PRGYNTDAAGVKRAFQHHD
#oth            ...2...121232132132.211.....1211112413411.1.1...12.13.1151.2
HQ1245A         :::::::::::NHII::DI:REV::::::K::::HD:E::::::::::V::::::::::N
VNG0382         :::A::::SAAS::AT:SM:A:V::::::::::::S:AA:::::::::V:::::::A:::
Hut0135         :::::::::::N::AV:D:::::::::::::::::S::Q:::T:H::::I:AV::LTR:G
Hmu0930         ::::::::AAFE::::::::R:::::::V:L:::::::E::::::::::V:AV::LRR::
rrnAC0707       ::::::::::::::::A:::::::::::V::::::::G::::T::::::V:AV::LD:::
NP0806A         :::::::E::::V:E::::::::::::::::::::E:E-:::T:H:::::::I:::::::
Hbo0823         :::::::::::EH:E::E::A::::::::A::::::DE::::::::::::::R:S:T:::
hla0082         :::V:::::A::::::A:::::::::::V::GPLRA::ADR:::H:::::::::::S:::

consensus       VALSG-TAVVVGAGGAGRAAAFALADAGASVHIANRTVERADALADDVPG-ATGHGLDDL
#oth            1222132............2..1...1124.21....323.431.3211111112..141
HQ1245A         ISID:YD::::::::::::::::::::::H:::::::::::ETI:T:IG:Q::AG:::TR
VNG0382         :S:::AQ::::::::::::::::::::::T:R:::::RAA::E::A::G::-:AV::G::
Hut0135         :::::::::::::::::::I::G:::E:MD:A:::::::T:H:::EE:::::S:::::A:
Hmu0930         :::D:::::::::::::::V::G:::E:M::R:::::::::HD::A::::::::::::E:
rrnAC0707       :S:::::::::::::::::V::G:::E:L::R:::::ESK::::::E::D::S:::::S:
NP0806A         :ER:::::::::::::::::::::::E:ME::::::::S::T:::TE::D::::::::E:
Hbo0823         :::ADRD::::::::::::::::::::E::::V::::A:::TE:::::::::::G::GT:
hla0082         IE:A:RD::::::::::::::::::::::T::V::::A:::VD:::A:::::::G:::::

consensus       -DLLADADVLVNATSVGM-DED--ATPVPADALHDDLAVLDAVYSPIETRLLRDAAAAGA
#oth            635232.11.111.1...11311161..1342..41.2......2.2.....11.2...1
HQ1245A         ::EIS:::I:L:::::::::P:SNQ::::QSY:::G:V::::::T::::::::E:T::::
VNG0382         PRS::::T:::H::T:::D:P:::TS::S:::::::::::::::::V:::::::::::::
Hut0135         DS::::::::::::::::::::::RS::::T:::A::::::::::::::::::E::::::
Hmu0930         H:TV::::::::C:::::::::::::::::::::G::S:::::::::::::::::::::G
rrnAC0707       S::::N::I:::C::::::E::::K:::::::::S:::::::::T:::::::Q:::::::
NP0806A         AE:VP::::::::::::::EA:::E::::KRH::EG::::::::A:L::::::E:D::::
Hbo0823         ::QVR::::::::::::::ES:::D::::RKY::::::::::::::::::::::::::::
hla0082         G:RI:G::::::::::::DEPE:::::::::H::G:::::::::A::::::::E::::::

consensus       TTIDGAWMLLFQGVEAFERWTGQDAPVEAMNAALRARL---
#oth            ..1.......1..11...1.1151..135.131..33.111
HQ1245A         ::::::::::Y:::V:::I::E::::IQQ:::::::E:EDA
VNG0382         ::::::::::Y::A::::::::L::::A::R::::::::::
Hut0135         ::V:::::::::::::::::S:::::::E::E:::E:::::
Hmu0930         ::V:::::::::::::::::::L::::DH::D:::D:::::
rrnAC0707       ::V:::::::Y:::::::::::E::::DR::GR::EH::::
NP0806A         ::::::::::::::::::I:::KA::::P::E:::SS::::
Hbo0823         ::::::::::::::::::::::R::::::::D:::SH:E::
hla0082         ::::::::::::::::::I:::A:::::::::::::E:E::