8 genomes BUD1034 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2461 - HVO_1514 HVO_A0173 Hbo0039 Hmu1214 Hut1348 hla1861 NP3362A HQ2697A

Pairwise sequence scores
Consensus score	1038	VNG2461	HVO_A0173	hla1861	HQ2697A	HVO_1514	Hbo0039	Hut1348	Hmu1214	NP3362A
572	VNG2461	1106	419	425	413	458	469	460	486	469
601	HVO_A0173	419	1952	429	439	492	505	458	478	428
688	hla1861	425	429	1307	508	579	532	485	521	490
682	HQ2697A	413	439	508	981	579	633	467	488	433
806	HVO_1514	458	492	579	579	1361	702	543	562	460
795	Hbo0039	469	505	532	633	702	1058	563	584	495
664	Hut1348	460	458	485	467	543	563	1113	605	506
686	Hmu1214	486	478	521	488	562	584	605	1031	621
610	NP3362A	469	428	490	433	460	495	506	621	1200

281 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
VNG2461         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_A0173       VIAKPKTTPRLPDHSTPMNRASVARVTRLVTVVGAAFVLAGLAVQVTTLRLGVPHLQWGL
hla1861         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2697A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1514        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0039         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1348         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1214         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP3362A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       -----------------------------------------VVYATRGLLDALLDMAADA
#oth            222221233333233313332323233332232433433455233123144412332321
VNG2461         :::::::::::::::::::::::::::::::::::::::MPP:::::A:VAV:CEL::::
HVO_A0173       RAASDAEVLGVGLWWVAVATRLVGPRRTQRRVGRERDPTRQA::V:::::::::GR::R:
hla1861         :::::::LRTRSPGRAARHPDCTRGPCARRSGSDRVGARLL:IHI::D::TV:::Q::ER
HQ2697A         :::::::::::::::::::::::::::::::::::::::::--------------:S::R
HVO_1514        MPNETADNDENPLDAEATPERTTEGETVEPRPSETAEPERRR:HV::::V:L:::::E::
Hbo0039         :::::::::::::::::::::::::::::::::::::::::::FI::::H:::::::S::
Hut1348         :::::::::::::::::::::::::::::::::MTAPGTTDPI:::A::I:V::EQ::ER
Hmu1214         ::::::::::::::::::::::::::::::::::::::::::I::::::VES::G:GR::
NP3362A         :::::::::::::::::::::::::::::::::::::::::M::I:::::A::CEL::ER

consensus       DPDSVSVVLAATPAGEFD---DALD-----------------LDPETPVLTHFYLPDAGG
#oth            2.332233134.2.3213222434311111111111111111122331121122413216
VNG2461         :::::::R::::::RDL:AGDETHT::::::::::::::::::::D::::SD::F:S::D
HVO_A0173       E:SRE:LS:GT:A:::L::::G:ES:::::::::::::::::::ATR::FS::VH:S::A
hla1861         :::AT:LR:S::R::::::::EDTG::::::::::::::::::::SM::V:::TPAGV::
HQ2697A         ::E:::A:::S::::::E:::::TG:::::::::::::::::V:SS::I:::::F:::S:
HVO_1514        E:S::NL:::P:::::::::::D:G:::::::::::::::::::::::::::::MAE::Q
Hbo0039         E:ER:T::::::::EA:E::::D:::::::::::::::::::V::::::::::::::::K
Hut1348         A::P:TIS:SV:A::D:-:::S:::::::::::::::::::::P:::::F::L::::::S
Hmu1214         :::::T:AVSV::::DL-:::PEA:::::::::::::::::::::T:D:F::::M:S::N
NP3362A         ::R::T:A:TV:::S:LAPAGP:A:DGSATVPARRNDVDLSA:Q:DAD:F:DM::::T::

consensus       SVTAVFGVDLGTPAGRGRGRFVSHPQGPLEVTKRDDLAAVVLVAVPPWDRDAVAAFDRAG
#oth            1233...2.12113232511.21..4.3343244.2121221211..1244432111.52
VNG2461         AL:S::::::AA:::QTA:::::::K:DHT::LA:::H:QL::G::::EPGE:R:HN:H:
HVO_A0173       A:RG::::::S:AP::TP:Q:::::W:::AA::::T:RE::::::::::D:C::::::::
hla1861         ::N::::::I:::::::GA::I:::N:F:G:S:::::::::::::::Y:D::::::::::
HQ2697A         :::::::::::::::S::A::::::::::AA:RE:TF::A::I:I::::V::C:::::EN
HVO_1514        ::S::::M::::::::::A::LT:::::F:L:E::G::::::L:::::E:RTL:::::::
Hbo0039         ::R:::::::::::::::A:::::::::D:P:RE::F::AI::::::::ESS:S::::S:
Hut1348         :INF:::::::::::QTQ:::L:::E:R::PAQS::FH:::F::::::N::SI:V:::DS
Hmu1214         ::S::::F:::::VAQSN:::::::E:R:D:::T:::HE:IF:::::::EESI:::::R:
NP3362A         :::::::M::S::G--SA:::I:::E::FGL::A:::HE::FI::::Y::::::::::R:

consensus       RRLELAVLDAEP-----------------PEESL--D----
#oth            66233512213.11111111111111111.33523242222
VNG2461         T:R:FV:V::D:::::::::::::::::::AADAP:-::::
HVO_A0173       ::RP:R:V::::CESFDEAISAAGPAASP:TS:AADG::::
hla1861         NGI:::::::A:::::::::::::::::::::::P:E::::
HQ2697A         QE:SMNII::D:::::::::::::::::::Q:T:TDNIEAE
HVO_1514        :K::::::::::::::::::::::::::::Q:E::::::::
Hbo0039         KQ:S:D:VE:::::::::::::::::::::T:::AR:::::
Hut1348         SPR::R:::V::::::::::::::::::::::H::::::::
Hmu1214         EE:S:T:::VA:::::::::::::::::::::A:::E::::
NP3362A         NV:TVT:VK:V::::::::::::::::::::G:V::EPLDT