8 genomes BUD1059 10 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC2242 HVO_1789 Hbo1716 Hmu0221 Hut2463 hla1849 hla2458 NP0290A HQ1117A HQ2214A

Pairwise sequence scores
Consensus score	690	HQ2214A	hla1849	hla2458	HQ1117A	Hut2463	HVO_1789	Hbo1716	Hmu0221	rrnAC2242	NP0290A
311	HQ2214A	680	313	315	293	246	274	278	267	266	244
385	hla1849	313	813	362	334	288	345	310	316	317	324
492	hla2458	315	362	724	469	354	386	402	406	394	388
473	HQ1117A	293	334	469	737	319	401	443	337	412	411
480	Hut2463	246	288	354	319	670	381	403	421	447	448
483	HVO_1789	274	345	386	401	381	710	451	383	440	454
519	Hbo1716	278	310	402	443	403	451	727	373	475	436
492	Hmu0221	267	316	406	337	421	383	373	695	498	449
560	rrnAC2242	266	317	394	412	447	440	475	498	685	531
517	NP0290A	244	324	388	411	448	454	436	449	531	685

109 symbols
consensus       ---------MSDRILRVNAYTTLDLLDGRAEGHDFEEDAFAVLNV-TAPRENPDHVELQL
#oth            111111111.42.222.1.1..1.12223251.2243335112..1234213.1414123
HQ2214A         :::::::::::N:::S:::::::::VSA:L:T::DSLSLDG:::::ATED:C::R:I:GI
hla1849         MSLPAVRPG:NE::TS:T:::::::V::A:L:::WT:NGSG:::::::SD:R::R::::F
hla2458         :::::::::::::L:::::::::::VE:::R::E::A::PG:V::::::::D:E::T:EV
HQ1117A         :::::::::::::L:::::::::::A:I::R::::DVNTLG:V:::::::K:::::T::V
Hut2463         ::::::::::A::V:K:::F::F:::E:SV:::G:A:E:::T::::RTA::::ES:S:E:
HVO_1789        ::::::::::P::::K:::::::::V:AS:T::::::S::::C::::S::KR::EIT:E:
Hbo1716         ::::::::::PN:L::::::::F:M::AE:V::::T:E::::::::::::K:::::R:E:
Hmu0221         ::::::::::V:::M:::::::F:::E::VK::G:D:::Y:::::S:DT::D::A::V:I
rrnAC2242       ::::::::::V:::MK::::::::::::EV:::G:::E:L::::::::::K:::::::::
NP0290A         ::::::::::V:::MK::::::::::::E::::G:::::Y:::::::S:KK:::::S:::

consensus       ELDNTELDALPPHADRVTLSAAQARELAAELESYADRVEAAQD------
#oth            .2.435216142...424.1131.133123.453.32124336443342
HQ2214A         :::TVGV::V:A::::IE:TPD::EAV:ES:QN::ED:RS:SH::::::
hla1849         :::GLDVER::N:::::D:TPE:::TV::A:TR::::I::DEGGNADSD
hla2458         :::::AI:D::A:::E:D::P::::T::EA:::T::::D:::NGDSSL:
HQ1117A         :I:H:TVEM::A:::E:::::SE::TI:DD:H:::::::N::SSGSDDA
Hut2463         ::::V::ESV::::::::::::E:::::::::AA:K:I:SED:S:::::
HVO_1789        :::W:Q::::A::::KL:::PEE::KI::D::EH::::::E:QD:::::
Hbo1716         ::::SQ::H::A:::K:::::SE::::SE::A:::E:::K::QETDGE:
Hmu0221         :M::::V::VE::::T:S::P:::::M:::::K::SK:D:SEE::::::
rrnAC2242       :M:::D:::VK::::S::::::::::::::::E::EK::T::SE:::::
NP0290A         :::::::ET:R::::K:R:::SE::T:::D::KH:EK::NES:::::::