8 genomes BUD1068 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC1251 HVO_1266 Hbo0281 Hmu1719 Hut0514 hla1929 NP4024A HQ1812A

Pairwise sequence scores
Consensus score	2890	Hut0514	NP4024A	rrnAC1251	Hmu1719	hla1929	HVO_1266	Hbo0281	HQ1812A
2325	Hut0514	2873	2063	2137	2227	1968	2076	2027	1969
2332	NP4024A	2063	2897	2238	2196	1934	2118	2001	1973
2370	rrnAC1251	2137	2238	2899	2380	1896	2053	1927	1957
2440	Hmu1719	2227	2196	2380	2920	1959	2085	2032	2040
2193	hla1929	1968	1934	1896	1959	2875	2074	2007	1879
2390	HVO_1266	2076	2118	2053	2085	2074	2906	2225	2068
2377	Hbo0281	2027	2001	1927	2032	2007	2225	2891	2341
2318	HQ1812A	1969	1973	1957	2040	1879	2068	2341	3216

426 symbols
consensus       MTD-----------------------------ELSDRARQVPPSGIRRFFELAEEMDDII
#oth            12422111111111111111111111111111321311443.1....1...1.123..11
Hut0514         ::I::::::::::::::::::::::::::::::::E:::TI:::::::::::::QQ::::
NP4024A         ::L::::::::::::::::::::::::::::::P:::VAD::::::::::::::::::V:
rrnAC1251       ::F::::::::::::::::::::::::::::::AA::VDS::::::::::::::::::::
Hmu1719         ::F::::::::::::::::::::::::::::::PA::VD:::::::::::::::::::::
hla1929         --M:::::::::::::::::::::::::::::R::::::DL:E::::K::::::AR::V:
HVO_1266        ::LGD:::::::::::::::::::::::::::Q::::VE::::::::K:::::::V::V:
Hbo0281         :S::::::::::::::::::::::::::::::Y::TL::ET::::::::::V::::::V:
HQ1812A         :::RQGHSASSIESEQANDEIRNPDHTSGNIHR::Q::K:T::::::::::::D:::::V

consensus       SLGVGEPDFSAPWAAREAAIDSLERGKTSYTANRGKRELREAIADHV-ERYDLQYDPDDE
#oth            ..........1..1..2...21..1.2....1...232..13.13321533213.1.21.
Hut0514         :::::::::::::S::::::A:::Q:::::::::::L:::::::G::ADAF::T::::::
NP4024A         ::::::::::::::::::::S:::::R::::::::::::::E:::D::R:WN::::::::
rrnAC1251       :::::::::::::S::::::A:::::Q::::::::::::::R:::YEAATHN::::::E:
Hmu1719         ::::::::::T::S::::::A:::Q::::::::::::::::R:::D:A:::::D::::E:
hla1929         ::::::::::::::::T::::::::::::::S:::MAA:::R::V:H:::::QT:A:T::
HVO_1266        ::::::::::::::::T::::::::::::::S:::M:::::::SER::T::GQE:::E::
Hbo0281         ::::::::::::::::T:::::::::R::::S:::M::::::::GR::::::Q:::::::
HQ1812A         ::::::::::::::::S::::A:::::::::::::RSD::AN:SE:::KQ:::E::::E:

consensus       ILVTAGASEAVDLAFRALVNPGDTVAVAQPCYISYTPGVTFAGGEVLDVPTRAEDDFKLT
#oth            11..1.1..12...2..2111.141.132.3.1..5.2231..21323.1..2221.211
Hut0514         ::::T:V:::::::L::I:D::::::::K:A::::V::AI::::DP:::V::RD:E::::
NP4024A         ::::::::::I::::::::::::::::V::::V::::::::::::::::::::::E::::
rrnAC1251       :::::::::GL:::::::L::::SI:I:::::V::V::A::::ID:I::::::::E::::
Hmu1719         V:::T::::G::::::::L::::K::::::::V::K:::::::AD:I:::::VA::::::
hla1929         ::::T::::::::::::::D:::::::HE:T::::G::IEL::::Q:T:::::::::A::
HVO_1266        :I::T::::::::::::F:::::V::IP::S:::::::AI:::::P:P:::::::E::::
Hbo0281         ::::::::::::::M::::DT::I:::PE:S::::E:T:S:::::A:S::::::A::AVG
HQ1812A         ::::::::::::::M::::D::E::::PK:S::::A:S::::::::RS::::::T::T::

consensus       REVLEASGAAEADALVLCYPNNPTGATMTRDELADVAAFAREHDLLVLADEIYAALRYED
#oth            313.2421.21.12.1311.......1.132.222..3.2.12.15.21..1.13.2.23
Hut0514         :::::::::::::V::MN::::::::::N:A::QP::E:::::::T::S::V::Q:S::H
NP4024A         Q:::YEE::D:::L::Y:::::::::::N:E:::E::::C::E:VD::::::::D:T:DG
rrnAC1251       Q::::S::::::::::Y:F::::::::::AE:M::::::C::N::::F::::::D:T::H
Hmu1719         :::::D:::::::::IF::::::::::::EA::RP::E:::::::::F:::::SE:S::H
hla1929         ::S:::::::D::L:::::::::::::::EE:Y:E::::C:DN::R:I:::::S::T:GT
HVO_1266        P:A:::A::D:::V::::::::::::V::D:::::::S:V:D:::V::S::::SD:::::
Hbo0281         YDD::RA::::::V::::::::::::V::::::::::E:::::::F::S:::::::::::
HQ1812A         Y:D:T:AN:S::S:::::::::::::V::::::R:::T:::::::F::S::::S::::D:

consensus       DHTSIATLPGMRERTVVFNGFSKAYAMTGLRLGYALGPPDAIDAMNRIHQYTMLSAPTTA
#oth            1.2...1311.....2.1......1....2.....11.33214...11...2.......1
Hut0514         :::::::::::::::I:::::::::::::::::::M::::V:A::::::::::::::::P
NP4024A         ::V:::EFD:::::::::::::::::::::::::::::A:V:S:::::::::::::::::
rrnAC1251       ::::::::::::::::::::::::F::::F:::::MA::E:VE::::::::S::::::::
Hmu1719         ::::::::::::::::::::::::::::::::::::A::E::T::::::::::::::::P
hla1929         E::::::Q:::::::::V::::::::::::::::::::T::::::::::::::::::::P
HVO_1266        ::A::::H:::::::I:::::::::::::::::::M:::G::::::KV:::A::::::::
Hbo0281         ::V:::::::::::::::::::::::::::::::::::AAI:::::::::::::::::::
HQ1812A         E:V::::::E:::::L:::::::::::::M::::::::QEV:::::::::::::::::::

consensus       QYAAIEALDSCDDEVEEMRRQYDRRRRFVLSRFEEMGLDCFEAKGAFYAFPECP--WDDD
#oth            .2..3..143.233142.25211...32.22..212.3.1.214....1..2211122.2
Hut0514         ::::::::ER:E:D:A:::N::N::::::::::::::V:::P:S::::::::S::::::S
NP4024A         :H::::::QT:RED:::::D::::::N::::::::::I:::::T::::V::K::::G::A
rrnAC1251       :H:::::::N:R:::TD:AA::::::KY::T::::::::::P:A:::::::::::::::A
Hmu1719         :::::::::N:ES:LR:::E::::::QL:::::D:::::::T:::::::::::::::::A
hla1929         ::::C::::R:::::A::VNE:N::::L:V:::N:::::T::PG:::::::D:-::GG::
HVO_1266        ::::L:::R::::S::::::E:::::::::A:::::::::::::::::V:::A:::DG::
Hbo0281         ::::L::IE::::A:D::::A::::::::I:::NDI:M::::::::::V::K::PG:E::
HQ1812A         :A::M::IN::EPA::K::QAF::::Q::I:::N:L:M::::::::::V::K::PG:E::

consensus       EAFAEALLEEERVAVVPGSVFGEGGEGHLRVSYATGMDDLKEAMDRIESFVS--------
#oth            22...4.12134..2...41..3213....1...11131.11.23.21412443211111
Hut0514         D:::::::::AG::::::N:::DA::::::::::::LG:::::LA:F:E:I:::::::::
NP4024A         GQ:::D:::A:Q::M:::DA::A:AS::::A:::::L:E:R:::::L:R:::::::::::
rrnAC1251       GE:::S::Q:K:::::::TA:::::S::::::::::L:::::::A:::::LN::::::::
Hmu1719         D::::::::A:::::::::A::V::D:::::::::::S:::T::::::::LADQ::::::
hla1929         :::::E:::AQG:::::::::::::::::::::::S:RE::::T:::AT::EGRD:::::
HVO_1266        :::::G::::QN::L::::::::::A:::::::::::RE:R:::::::AY::D:::::::
Hbo0281         ::::::::Q::K::L:::R::::S:::::::::::S:SE::T:LN::::::RE:::::::
HQ1812A         :E:::::IH:::::L:::R:::D:::::::::::S::::::T:LT:::::LESYPTSASL

consensus       ------
#oth            111111
Hut0514         ::::::
NP4024A         ::::::
rrnAC1251       ::::::
Hmu1719         ::::::
hla1929         ::::::
HVO_1266        ::::::
Hbo0281         ::::::
HQ1812A         EVSDTA