8 genomes BUD1075 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0198 HVO_1098 Hbo0603 Hmu0696 Hut0348 hla2631 NP1646A HQ1510A

Pairwise sequence scores
Consensus score	3129	HQ1510A	hla2631	HVO_1098	Hbo0603	NP1646A	Hut0348	rrnAC0198	Hmu0696
2069	HQ1510A	3481	1913	2119	2119	1624	1671	1580	1677
2217	hla2631	1913	3447	2065	2100	1729	1751	1798	1854
2249	HVO_1098	2119	2065	3169	2258	1764	1836	1789	1807
2259	Hbo0603	2119	2100	2258	3311	1841	1790	1772	1838
2282	NP1646A	1624	1729	1764	1841	3118	2142	2063	2202
2451	Hut0348	1671	1751	1836	1790	2142	3171	2435	2546
2469	rrnAC0198	1580	1798	1789	1772	2063	2435	3331	2630
2555	Hmu0696	1677	1854	1807	1838	2202	2546	2630	3158

502 symbols
consensus       MSSAD-----------------------------PPVRRLADWDHDRLARLAAEHGTPLY
#oth            .2673334443433322222222222221111111311.112..413.341.41211...
HQ1510A         ::TI:TEQTTDNTDSG::::::::::::::::::A:I::::A::T:S:CN::::FE::::
hla2631         ::DN:AAAESPLS::::::::::::::::::::::S:::VS:::A::::G::V:::::::
HVO_1098        ::GGG::::::::::::::::::::::::::::::A::::S:::REH:LS::G:F:S:::
Hbo0603         :TP::GGSGADASAEAESDAGTEAESEPNTDAEN:QI:::SE::A:::::::D:Y:::::
NP1646A         :T---::::::::::::::::::::::::::::::::K::::::G:::E:::EA::::::
Hut0348         ::HS-::::::::::::::::::::::::::::::::::::::::EQ:LA::::YE::::
rrnAC0198       :A:WGAACIETEPLLAADTVVSPMSHDS:::::::::::::::::E::EAV:::::::::
Hmu0696         :::DS:::::::::::::::::::::::::::::::::::::::::::::::E:::::::

consensus       VIDLDRVRENYARLAEAFPDAHVMYAAKAHTGRAVLETLREAGADIECAAAGELQRAIDA
#oth            .5143.121.23.152..231312..2..12.1..1342212.312...12..141.13.
HQ1510A         :::AQ:::::C:::LD:::A:TIR::I:::S:Q:::KVI:D::I:V:::S:::VKA:LA:
hla2631         :Q::::::::SE::R::::::D:R::V::::::::::AV::::L:A:::S:::VD::LA:
HVO_1098        :T::R:::::CL::R::::E:::S::V:::A:::::::V::::V:A:::S:::VE::L::
Hbo0603         :::T:::Q::C:::Q:::SAEE:R::V:::::::::::V::::LAA:::S:::VE::LN:
NP1646A         :M:H::I:A::::FS:::DF:::::::::N:::::VR::YD:::::::::::::Y:::E:
Hut0348         :LETG::QA::R:FDA:::::E::::::::::::::SA:LDV::::::::R:::::::E:
rrnAC0198       :V:::::A:::E:F:A::::::::::::::::Q:::SK:L:T::::::::W:::::::::
Hmu0696         :L:V:::AA::R:F:A::::::::::::::::::::SG:L::::::::::::::::::::

consensus       GADGNRLQYTAVNPPARDLDYAVDLAEEHPELTITVGAADTFDRLEERGFDGRLAIRINP
#oth            .3513322.......22...321431434131.1.2..31.41..32..11..112.2..
HQ1510A         :FN:::I:::::::::::::AIINWWQ:NKQ::::::::::VE::Q::::::::C::V::
hla2631         :FG:D::H:::::::::::::V:GV::AE:D:::::::V::L:::A:::Y:::VCV:V::
HVO_1098        :FP:E:VR:::::::DA:::HV:SRW:SN::M:V:::::::I:::R::::::::CL:A::
Hbo0603         :YE:SEI:::::::::::::HV::RWRD:::::V:::::::A:::R::::::::C::A::
NP1646A         :VAPED::::::::::G::::::::W:DT::::::A::EM:L::::A::::::::L:V::
Hut0348         :::P:T::::::::::A::::::E::D:Y:G::::G::R::::::QA::Y:::V::::::
rrnAC0198       :::P:T:::::::::D::::R::E::A:::G::::G::R::::::::::YN::V::::::
Hmu0696         :::P:T:::::::::GG:::::::::D:::G::::G::E:::::::D::Y:::V::::::

consensus       GIGAGHHEKVATGKDAKFGIPYDRVPELAADARERFDLVGLHAHAGSGILGDDLDDHRRA
#oth            11.1......2..23....2.21213221434122..1..2...1...12522114.312
HQ1510A         NV::::::::T::AN:::::::E::S:::TQWATE:::::I::::::::S:E::SS:EEL
hla2631         :V::::::::R::GA:::::::::AA:ATR::A::::V::I::::::::DP:Q::S::EM
HVO_1098        :V::::::::T::GH::::::I::::D::::V::E:::::V::::::::S::::SA::EL
Hbo0603         :V::::::::R::AN::::V:::D:::::ESIADD::::::::::::::S::::SN::EL
NP1646A         :::T:::::::::::::::L::EE:EAV:EA:::::::::::::V:::V:SG:::::E::
Hut0348         :::T:::::::::::::::::AE:::D::::L::::::::::::V:::V:TGEV:E:A::
rrnAC0198       :::T:::::::::::::::::::E:::V:::V::::::::::::::::V:H::::::C::
Hmu0696         :::T:::::::::::::::::::E::A::D:L:D::::::::::::::V:RE:::::C::

consensus       VRRMADLAREV--GDG------DLEFVDVGGGFGVPYREDEPPLDIEAVAEATREAVGDL
#oth            24111312142345431111113111..2........122411..25411141.212131
HQ1510A         ::::GT:::TITECA:::::::S:::::::::::::::AND:::::HT:::R::D:L:TV
hla2631         :T::GG:::DLTDP:EGGVAPV:I:Y:::::::::::K::A:A::LP::::::::::AP:
HVO_1098        ::::G::::::::--:::::::G::::::::::::::::::::::LA:::D:::::L:EV
Hbo0603         ::::GE:T:N:ESRV:::::::S:::::::::::::::A::::::LDS::D:::::L::V
NP1646A         LQ:V::::ER:::--:::::::::::::L:::::::::P::E::::::A::MV:RVTA::
Hut0348         LGKV::::::::::::::::::::::::F::::::::::::::::::V:::TV:::::::
rrnAC0198       IGKV::MG:::IADGA::::::E:D:::F:::::::::::VE:::M:I:G:KV:::::::
Hmu0696         IAKV:E:::::::::S::::::::::::F::::::::::ETE:::MQ::G:RV:::::::

consensus       DA--TLALEPGRYVVADAGVLLTRVNTVKETPETTVVGVDAGLTTLIRPAMFDAYHPIRN
#oth            31113313.....1....131122...1.221221...1..112211....111..3.2.
HQ1510A         :::::::I:::::::::::::::::::I:SAR::::::::::M:::L::::Y::::E:E:
hla2631         P:GVD::I:::::::::::::::::::::P::DER:::::::M:D:L::::Y::::::::
HVO_1098        ::::Q::V::::::::::::::S:::::::V:::::::I:::M:::L::::Y::::A:S:
Hbo0603         SG:::::V::::::::::::::::::::::A:DA::::::::M:::L::::Y::::E:::
NP1646A         :::::V:::::::L:::::A:V:::::I::::::R:::::::::SM:::::::S::H:::
Hut0348         N::::MKF::::::::::ELI:A:::::::A::::::::::S:S:::::::::S::::::
rrnAC0198       ::::QVK:::::::::::ECI::E::::::::AA:::::::S:A::::::::GS::::::
Hmu0696         S:::RIK:::::::::::ELI::T::::::::A::::::::S:A:::::::::S::::::

consensus       V-SAP------------DRDAEPVSVAGPCCESADVFATDRPIARPERGDLLAIGNAGAY
#oth            213321111111111112333533211..3.112.22122.4123.313121.2.21...
HQ1510A         ISAS:::::::::::::TT:SM::TI:::I:::S:I::EG:S:SA:T:::II:::T::::
hla2631         L:GGGRESDGSDAPAID::S:T::T::::I::TG:TLC:::AL:D:V::::::V:I::::
HVO_1098        L::R::::::::::::::A:PVSTI::::V::TS::::DG:DLPD:::::C::L::::::
Hbo0603         ::::A:::::::::::D:VE:ISAT::::I::::::MCEN:LL:Y:R::N:::V::::::
NP1646A         ::TGG::::::::::::::EPVES::G::L:T:::::C:::::P:::AD:::::::V:::
Hut0348         :::::::::::::::::::AD:A:::G::::T::::::::::::::::E:I:::::::::
rrnAC0198       ::T::::::::::::::E:E::::::G::::T:::::C::::L:::::T:::::::::::
Hmu0696         ::::::::::::::::::::PH:::IG::::T::::::::::::::::T:::::::::::

consensus       GYELASQFNSRPRPAEVAIEGGGARVVRRRETLADLTRLEREASE---------------
#oth            .111.221111...2..2322253222.1...3411242.34353354433222211111
HQ1510A         :::M::TY:A:::::::IYDDNT:K:A:::::RDE:DV::TSSD:HSVSLSSVVSHSHSS
hla2631         :::M:T:Y::::::P:::LDD:T:AI:::::::D:::TV::D:NRNRADRTEAGR:::::
HVO_1098        :::M::TY::::::P::VLDAD:P:LA::::::H:V:A:::T:::HIPN:::::::::::
Hbo0603         :::M::TY::::::::::LS::A::L:::::::T:::E::A----:::::::::::::::
NP1646A         :IN:::::H:Q:::G::::::DNE::T:::::FE::::::D:::GAE:::::::::::::
Hut0348         :::::NN:H:Q::::::::::D:::I::::::M::V::V:D:TAGAPDAERE::::::::
rrnAC0198       :::::N::H:Q:::::::F:::ET::::E::::::V::M::----:::::::::::::::
Hmu0696         :::::N::H:Q:::::::::D:DE::::::::M::VV:V:D::G::::::::::::::::

consensus       ----------------------
#oth            1111111111111111111111
HQ1510A         VAPESTMSSSSTGDTPPGGESQ
hla2631         ::::::::::::::::::::::
HVO_1098        ::::::::::::::::::::::
Hbo0603         ::::::::::::::::::::::
NP1646A         ::::::::::::::::::::::
Hut0348         ::::::::::::::::::::::
rrnAC0198       ::::::::::::::::::::::
Hmu0696         ::::::::::::::::::::::