8 genomes BUD1082 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC2679 HVO_0046 Hbo1447 Hmu3089 Hut2205 hla0672 NP5258A HQ3714A

Pairwise sequence scores
Consensus score	2168	HQ3714A	hla0672	NP5258A	HVO_0046	Hbo1447	rrnAC2679	Hmu3089	Hut2205
1731	HQ3714A	2236	1586	1580	1670	1715	1623	1638	1652
1813	hla0672	1586	2337	1707	1644	1636	1714	1711	1616
1827	NP5258A	1580	1707	2144	1658	1662	1681	1755	1647
1875	HVO_0046	1670	1644	1658	2176	1794	1714	1771	1730
1889	Hbo1447	1715	1636	1662	1794	2176	1761	1743	1732
1884	rrnAC2679	1623	1714	1681	1714	1761	2432	1894	1705
1946	Hmu3089	1638	1711	1755	1771	1743	1894	2346	1797
1821	Hut2205	1652	1616	1647	1730	1732	1705	1797	2191

352 symbols
consensus       ------------------MNVGLLYSRIRRDEKLLLSELRDRGHEVTKIDVRKERFNIHE
#oth            111111111111111111231.2......2......4...2.1.112...1.111.2352
HQ3714A         :::::::::::::::::::::::::::::Q::::::::::S:::TI::::I:D:Q:D:AN
hla0672         LGRVDGDDRHDRDTRVVD:QI:I::::::K::::::G:::::::::E:::::::::GLES
NP5258A         ::::::::::::::::::::::V:::::::::::::::::::::::::::::::::GV::
HVO_0046        ::::::::::::::::::LH::::::::::::::::N:::::::::::::::::Q:DLT:
Hbo1447         :::::::::::::::::::K::::::::::::::::T:::E:::::A:::::::Q:::S:
rrnAC2679       :::::::::::::::::::K::::::::::::::::::::E:D::IE::::::QQ:::::
Hmu3089         ::::::::::::::::::::::I:::::::::::::E:::::D::::::::::Q:::MS:
Hut2205         ::::::::::::::::::V:::I::::::Q::::::::::E:D::::::::::Q::GLDS

consensus       PPAAFEDVDIVVDRCLATSRSLYATRFLDAYDIPVVNSPETADICADKVKNSLALADAGV
#oth            21131221.1.1....1....4.2.3.231.11.11.3231122.1..13...1.34.21
HQ3714A         :::::TQ::V:L:::::::::Y:I:Q::E::G::II:DAT:::V:::::::::::QS:E:
hla0672         TT:NV::L::::::::S::::::::K:::S:GV::::::::G::::::A:::::::E:DI
NP5258A         A::V:DG::::::::::::::Q:I:::V::::V::::D::::AV::::AR:::V::E:D:
HVO_0046        ::ES:DGL:V:::::::::::I:I::::KS:G::::::H:::::::::A:::::::::::
Hbo1447         :::::::::::L:::::::::::T::::::::::::::AD:::V:::::::::::EQ:::
rrnAC2679       A:E::::L:::::::::::::V:::K:AE::GV::::G::V::T:::::N:::::EA:::
Hmu3089         :::::DG::::::::::::::V:::K:VE:::V::::T:G::E::S:::::::::V::D:
Hut2205         ::E::::::::L:::::::::::::E::S::::::::TH:::ET:::::T:::::QQ:::

consensus       PTPNTEVAFTKDSAMESIEEFGYPCVLKPVVGSWGRLMAKIDSRSAAEAILEHKETLGHY
#oth            ...3.2.1..212.121114.....11...1...........143.........2...1.
HQ3714A         :::R::::::T::::::::R:::::I:::::::::::::::::A::::::::::S:::::
hla0672         :::A:::T:::EA:::::::::::::::::::::::::::::T:N:::::::::::::::
NP5258A         :::A:::::::E:::::::S::::::::::I::::::::::::KD:::::::::::::::
HVO_0046        :::::K::::V::::DIV:::::::::::::::::::::::::E::::::::::S:::N:
Hbo1447         ::::::::::T::::K::KK::::::V::::::::::::::::PA:::::::::A:::::
rrnAC2679       :::::D::::::A:L::::K::::::::::::::::::::::::::::::::::::::::
Hmu3089         :::::D::::::A:::::::::::::::::::::::::::::::::::::::::::::::
Hut2205         :::T::::::::T:L:I::D::::::::::I:::::::::::T:D:::::::::A:::::

consensus       EHKVFYIQEFVEKPGRDIRVLATDGEPIAAMVRSSDHWLTNAAKGAETDAFELDDRALEL
#oth            1..1..1....3.....1.11.2....11..2.11........1.122441211.1131.
HQ3714A         :::::::::::S::::::::::A::::::::T:TA:::::::::::::AP:S:::::R::
hla0672         :::::::::::D:::::::A::V::::::::T:::::::::::::G::KS:D::::::D:
NP5258A         ::::::::::::::::::::V::::::::::A:::::::::::Q::::E:I:IT:EMAD:
HVO_0046        :::::::::::::::::::::::::::V::::::::::::::::::SV:E:::::::K::
Hbo1447         Q:::::V::::K::::::::::V::::::::T::::::::::::::DAE::::::::K::
rrnAC2679       :::I::V::::::::::M::::V:::::::::::::::::::::::::NE::::::::::
Hmu3089         ::::::V::::D:::::::::::::::V:::::::::::::::::::::T::::::::::
Hut2205         ::::::V::::::::::::::::::::VG::::::::::::::::::::::::::::K::

consensus       VERASDAVGGGLLGIDLMETGD------------------------------------DY
#oth            .34..2.....1..1....1.31111111111112322222222112221211234333.
HQ3714A         :AD::K:::::::::::::::G:::::::::::::::::::::::::::::::::::G::
hla0672         :::::E:::::M::V::::V:G::::::::::::::::::::::::::::::::TGSGE:
NP5258A         :::::E::::::::::::::::::::::::::::::::::::::::::::::::::::S:
HVO_0046        :KQ:::::::::::V:::::::::::::::::::::::::::::::::::::::::::::
Hbo1447         :QK:::::::::::V:::::::::::::::::::::::::::::::::::::::::::::
rrnAC2679       ::K::::::::::::::::V:VSQSDTQDASGESEAQRASNANGDSREQGEPRAREFE::
Hmu3089         ::Q::::::::::::::::::V::::::::::::DEDSEAGTASDSASGGKPRVGDPE::
Hut2205         :AE::E:::::::::::::::E::::::::::::DGD:::::::::::::::::GNPTG:

consensus       TVHEVNHTVEFKALNDAVDVDVPAEVVDWLETKAAA--AQ--AEVTA-----
#oth            ....1.........131223...25.1....422441135634122211111
HQ3714A         ::::I:::::::::::::ST:::G::I::::MAID:LSDNNSN:IITDAETT
hla0672         ::::::::::::::DA:T::::::K::::::A:V:::::DG:E:::::::::
NP5258A         :::::::::::::::EVT:::::SV::::::SRVRD::--::V:::::::::
HVO_0046        ::::::::::::::::::EA::::T::::::A::DG::::SL:::S::::::
Hbo1447         :::::::::::::::N::EK::::A:::::::::NG::DAKV::A:::::::
rrnAC2679       :::::::::::::::EVT::::::K::::::Q:::T::ETD:::::::::::
Hmu3089         ::::::::::::::DEVS::::::::::::::::--::E:E::G::::::::
Hut2205         ::::::::::::::::::ET:::GQ:::::::::--::--::-G:SE:::::