8 genomes BUD1083 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC2437 HVO_1937 Hbo1806 Hmu0314 Hut2095 hla1585 NP1056A HQ3154A

Pairwise sequence scores
Consensus score	2466	Hut2095	hla1585	HQ3154A	HVO_1937	Hbo1806	NP1056A	rrnAC2437	Hmu0314
1673	Hut2095	2446	1476	1377	1515	1434	1646	1520	1531
2019	hla1585	1476	2509	1615	1771	1742	1652	1591	1560
1786	HQ3154A	1377	1615	2538	1762	1871	1515	1381	1398
2069	HVO_1937	1515	1771	1762	2503	2001	1673	1578	1635
1976	Hbo1806	1434	1742	1871	2001	2728	1553	1504	1501
1854	NP1056A	1646	1652	1515	1673	1553	2490	1597	1669
1814	rrnAC2437	1520	1591	1381	1578	1504	1597	2459	1848
1854	Hmu0314	1531	1560	1398	1635	1501	1669	1848	2447

363 symbols
consensus       ---------MLGIELTPEHPVERLVELGVRAEAAGYDAVFASCHYNNRDPFAALSRLAAA
#oth            1111221211312.....112552332123..4312.332312......1134.332.63
Hut2095         ::::::::::KA::::::::::EVRR:AE:::RT:F:TI:::N::::::::QT::SI:::
hla1585         :::::::::::::::::::DLH:::D:::::::::::::YST::::::::W:F::Q::T:
HQ3154A         MRDIAPDRPT::V:::::V:IPTV:DR::I::D::::GA:I:::::::::::::A:::GQ
HVO_1937        ::::::::::::L::::::::DD:::::AQ::RE:::SC:V:::::::::::V:A::::E
Hbo1806         ::::MSDDPT::::::::::IPAV::R:::::K::::TA:V:::::::::::::::::DE
NP1056A         ::::::::::I::::::::::S:IA:::EQ:::E:F:T:::::::::::::V::D:I:RR
rrnAC2437       ::::::::::YA:::::::::AQ:ASFAEQ::SNAL:::YV:H::::::Q:MS:TAM:ER
Hmu0314         ::::::::::YA::::::::::T:T::A:E:::E:F:::L::H::::::Q:M:::SM:Q:

consensus       TDEVRLGPGVANPYETHPVTLASRVATLDELSGGRAVFGIGPGDPSTLRNLGLEDERGLR
#oth            .13232...11....2...1..212..12.313..111.2.1..31..4...222122..
Hut2095         ::S:Q:::::V::::::::R::::M:::::S:D::G:::::A::A:::A:::V:RDSP::
hla1585         ::S:::::::::::::::::::::::::::::E::::::L::::::::::::::::::::
HQ3154A         ::TLHI:::::::::L:::::::KT::VA::TN:::L:::::::::::Q::::T::::::
HVO_1937        ::DI:::::::::::L::::::GK:::VA:A::::GLL::::::::::::::::::::::
Hbo1806         :E:L:::::::::::M::::::AKT::VA:::E:::::::::::::::::::::::::::
NP1056A         ::T:::::::::::::::::::::::::::A:D::::L:V:A::A:::E:::F:R::P::
rrnAC2437       ::::L::::I::::::::::::::::::::::::::::::::::K:::S:::FDHDDA::
Hmu0314         :::LLV:::I::::::::::::::::::S:V:::::L::V::::EA::S:::FDHD:P::

consensus       RVLEAFKVAQKLWDGERVDHDGTFEAADAGLNYDVP-G-EIPVYVGAQGPHMCRMAAKHA
#oth            2...1.12.23112.1113.1...3.52.11.132221111.111.11....3..11...
Hut2095         ::::T:::::Q::T:DT:::::::R:T::S:::A:-::::::::::::::::L::SG:::
hla1585         P::::::T:::::A::::::E:::D::G:::::EP:Q:AD:::H::GE::::::::::::
HQ3154A         S::::::S:ED::A:::IT:E:::::N:::::FS::::::::::I:GE:::::::SG:::
HVO_1937        S:::::::::::::::::S:::::::T:::::F:::::::V:::::GE::::::::G:::
Hbo1806         S:::::::::RV::::::S:::::::QN::V:F:::::::::::::GE::::::::G:::
NP1056A         ::::T:::::D:YA::::::::::R::::::::ADTV:::V:A:::::::::I:::::::
rrnAC2437       ::::T:TT:R::::::::N:::::::V::::::E:-:D::::::::::::::T:::::::
Hmu0314         ::::T:::::R:::::::::::::Q:R::::::::-::::::::::::::::T:::::::

consensus       DGLLFNGSHPADLAWAREQVDEGIADRPD----------------------ERGEFDLAA
#oth            ..2.3.11..3.22.12212241531..2111111111111111111111142221222.
Hut2095         ::V:V:A::::::S:SADRIE::RSE:::::::::::::::::::::::::D::DL:V::
hla1585         ::::::::::K::::::::A:D:L:::::::::::::::::::::::::::H::D:::I:
HQ3154A         ::::::::::::::::SDR:A:::E:::S:::::::::::::::::::::::YD::E:L:
HVO_1937        ::::::::::D::::::::::I:VE::::::::::::::::::::::::::S::::T:::
Hbo1806         ::::::::::D:V::::AR:E::::E:::GGDAGNDGDSGDDGDSGDDGNTDTAD:E:L:
NP1056A         ::V:L:::::R:FE::AD:::A:LE:::::::::::::::::::::::::::::S::F::
rrnAC2437       ::A:Y::A::K:::::::::E:MADE::E:::::::::::::::::::::::Y:::::::
Hmu0314         ::A:Y::A::R::E::S::AAK:E:::::::::::::::::::::::::::A::::::::

consensus       YASVSVAEDAAAAREAARPPVAFIAAGAAPPVLDRHGIDAARADDIGDAISAGEFSEAFD
#oth            ..1..1221322..1...1...1122121....1..21.233.441.43131.3.42.11
Hut2095         ::::::::SEDR::::::::::::VGST:::::::::L:HD::EA::N:VQH:D:ET::E
hla1585         ::A::::::E:::::::::::::::G:::::::K:::::P:A:SEV::RV::::::A::E
HQ3154A         :::::::D::E:::::::::::Y:T:::::::::::N:::SL:KS::KK:G::D:::::E
HVO_1937        ::::::S:::D:::::::::::::::::::::::::::::D::S:::EK::::N::::::
Hbo1806         :::::IDS:RE::::::::::::::S::::::::::::::SL:::::KK::::A::::::
NP1056A         :::::::D::E:::A:::::::::::::::::::::D::H:V:EQ:::H::::A:D::::
rrnAC2437       :::::::::E:E:::::::::::V:::SP::::::::::HEA:::::Q:::::::TA:::
Hmu0314         :::::::::G::::::::I::::::::SP:::::::DL::E::REV::::A::::RA:G:

consensus       AVTPAMIDAFCIAGTPETVADRMAAVLEHADGVVVGSPLGPDLETAIDLAAAALRSARR-
#oth            3.111.11..21..1233.31132324222.13121..2..3214.14.11415343654
Hut2095         ::::E:::::A::::KA:::::IEEAMN:V:SF:AA:::::::::::E:::E::ED:TAT
hla1585         R:::E::::::M:::::I:RE:A:::A:::::L:::::::::::G:V::::E:VDGLF-:
HQ3154A         ::::E:::::::::DLTA:T:Q::G:::QT::II::::I::TP:Q::E:::T:FEQ:H-:
HVO_1937        L:::::::::SM::::DD:::::D::::::::::::::V:::::E::T:::::Y::TN:H
Hbo1806         L:::::::::SM::::D:::::::::F::::::::::::::NPDE::T:::D:T:R::SH
NP1056A         ::::::LE:::::::::::GEQIDD:::Y::SF:A::::::::DA:VR::GS::Q:RIDR
rrnAC2437       G::E::L::::::::::A::E:T::LE::::S::FA::::::V::::::LG:V:DRRS::
Hmu0314         ::SE::::::::::::::::E:TD:L:DY::S::FA:::::E:::::S:LGS:A::T:LA

consensus       ---
#oth            211
Hut2095         :::
hla1585         :::
HQ3154A         :::
HVO_1937        R::
Hbo1806         RSR
NP1056A         A::
rrnAC2437       :::
Hmu0314         :::