8 genomes BUD1090 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC1430 HVO_1144 Hbo0413 Hmu1739 Hut1410 hla2721 NP3232A HQ2357A

Pairwise sequence scores
Consensus score	1073	NP3232A	Hut1410	hla2721	rrnAC1430	Hmu1739	HQ2357A	Hbo0413	HVO_1144
726	NP3232A	1103	610	560	590	569	519	559	575
717	Hut1410	610	1108	526	610	602	504	548	567
697	hla2721	560	526	1097	582	621	549	600	560
796	rrnAC1430	590	610	582	1147	689	512	579	593
789	Hmu1739	569	602	621	689	1064	557	562	585
691	HQ2357A	519	504	549	512	557	1215	632	650
730	Hbo0413	559	548	600	579	562	632	1101	705
784	HVO_1144	575	567	560	593	585	650	705	1124

165 symbols
consensus       -----------MDRRQFLATTGA----AAAAGLAGCLGGG---ASDDDYDVGMTANAFRP
#oth            1233333332344..32.244152212132222...2242111454532.1..215114.
NP3232A         :::::::::::::::A:::::::::::::::SV:::::R::::L::E:F:I::S::::L:
Hut1410         ::::::::::MI:::T::::::-:::::L:T:::::::R:::::DSGNH:I::SSS::L:
hla2721         ::::::::::::H::R::RRI::AGGV::TTA::::SSV::::-GEPG:::::V:DGY::
rrnAC1430       ::::::::::::::::::RAA:P::::::V:::::::::::::SA:T::::::S:K::::
Hmu1739         ::::::::::::E::AY:R:VAG:::::S:V::::::::L::::ESR:::::::S:::D:
HQ2357A         MNDKAVNNTDTPS:::V:TSF:TGVGAVMTTSI:::::::SEPG:G:A:::::::I:YT:
Hbo0413         ::MQERQRADGSS::R:::GI:S::::V::::::::STS::::--QG::::::::V::N:
HVO_1144        :MRDHGSSNGGRT::::::A:::::::::T::::::ATLT:::::G::F:I::::V::D:

consensus       AEITVEAGDTVVWRNTSSRGHTVTAYEDGIPDGADYFASGGYDTEQAARDAWHNSLGGLI
#oth            5332142.22.1.5.11322.1....1341.13141..1.1112143..23261461.42
NP3232A         E:YEIDV:E::::G:NG::::::::::NS::ED:T::::::::D:GT:::D:::TA::N:
Hut1410         ::LR::P:T::::K:::THA:::::::NTL:::TE:::::::E:::G:::::YE:G::A:
hla2721         ::L::AV::::::E:::A:T:::::::G:::EA::::::::F:D:KT::T::::DF::AL
rrnAC1430       VQ::::P:T::R:L:::KQ::S::::::D:::E::::::::F::::::::N:G::S::TM
Hmu1739         :::::A::::::::::::HA:S:::::::::::::::::::F:D:PS::EG:T:ATD:SL
HQ2357A         Q:::IT::ES:::Q:::::::::::::S::::A:S:::T:::E::D:::E:FR:D:D:::
Hbo0413         SSL::SV::E:::Q::::::::::::D:R:::D:EF::::D:ESTK:::::FN:EI::::
HVO_1144        PTV::::::E:::::::::::::::::GTL:E::AF::::::E::::::::YS:::::::

consensus       YSGDTFSHTFEIPGEYEYLCIPHERGGMVGTIVVEE---------
#oth            45.332311.232.416.2.....531.31115.33332222111
NP3232A         PP:E::A:::NT::DHH:V:::::P:::I:V:R:R:P::::::::
Hut1410         :A:K:::::::E::R:S:V:::::SSN:A:V:L:GDVGEADS:::
hla2721         E:::R:T:::::A:R:D:V:::::T:::YA:VF::::::::::::
rrnAC1430       :E::D:T::::TV:::A:F::::::A:::::V::T:NPDTAASGE
Hmu1739         :Q:::Y:::::VA:Q:R:F::::::::::::V:::-:::::::::
HQ2357A         DG:E:WEY::D:::T:::::::::QQ::I::VT::PVE:::::::
Hbo0413         D::QS:::::::::::Q:::::::AQ::::::I::::::::::::
HVO_1144        G::E:YTYS:DV::::::::::::QA:::::::::::::::::::