8 genomes BUD1094 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0414 HVO_1475 Hbo0074 Hmu1375 Hut1221 hla1773 NP2236A HQ1868A

Pairwise sequence scores
Consensus score	1577	HQ1868A	Hut1221	hla1773	rrnAC0414	Hmu1375	NP2236A	HVO_1475	Hbo0074
1048	HQ1868A	1672	969	991	931	896	959	979	1094
1212	Hut1221	969	1593	986	1061	1077	1054	964	1076
1157	hla1773	991	986	2526	942	988	1075	1027	1057
1257	rrnAC0414	931	1061	942	1587	1173	1097	1061	1079
1182	Hmu1375	896	1077	988	1173	1587	1069	974	982
1246	NP2236A	959	1054	1075	1097	1069	1616	969	1057
1228	HVO_1475	979	964	1027	1061	974	969	1573	1189
1304	Hbo0074	1094	1076	1057	1079	982	1057	1189	1577

353 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HQ1868A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1221         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla1773         MGSKRRSAAVARPRSNRSSSTPPTSKAPRQNTSETSKPSSPPAATSPQPSLSRPGSTAAT
rrnAC0414       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1375         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP2236A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1475        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0074         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HQ1868A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1221         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla1773         RLPLSARPTGSGNLSAPRPSSVPVGSRSGSTKSPIGTRPSRRCRRSPSARAAKASNSFAS
rrnAC0414       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1375         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP2236A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1475        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0074         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ---------MATKRALAQQLAVVAGFENPRAALEQYPTPPDLAAHLVHLADLQGDIEGRT
#oth            111222222121123.122.2..2..14.524....2...32...21.3...31.1513.
HQ1868A         ::::::::::SS:AS:ETE::::S:::S:QIK::::::::EI:::VI:I::::D::ID::
Hut1221         ::::::::::S:::Q:::::G::V::DE:A::::::R:::TV::::::::::ND:VA:::
hla1773         TTGRLPPDR::S::S::TK:G::::::A:S:::::::::::::::V::::::H:::D:::
rrnAC0414       ::::::::::P::S::::::::::::D::::S::::R:::::::::::T:::::::Q:Q:
Hmu1375         ::::::::::S:::::::::G:::::DD:::P::::R:::E:::::I:::::R::::D::
NP2236A         :::MTDGNTG::R:R:::E::::::::D:T:P::::H::::::::I::V:::::::VD::
HVO_1475        :::::::::::::A::EA:::::::::::KVS::::::::::::::::::::R:::::A:
Hbo0074         :::::::::::::A::ET::S:::::::::VE::::::::G::::V::V:::N::V::K:

consensus       VVDLGCGTGMLALGAALRGPARVVGVDIDPDALSTARENERRVGATTPVSWVRADATQL-
#oth            12...2.....3.1..1.1.3123.212.331.31.43.33111241314.221..1421
HQ1868A         II:::T::::::::::F:::NQII:I:::RS::QV:QT:QS:::T:ASIE:IL::::::S
Hut1221         :::::::::::::A::::::SQ:L:::V::SP:::::A:R::I:TQ:T:::::::::EP:
hla1773         :L:::T:::::::A:::::::::F:IEL:RG:::::I::::::A:SAS:H:IQG:::R::
rrnAC0414       :::::::::::S::::::S::::::L::::AP:::::::::K::S::::::::::::MA:
Hmu1375         I::::::::::T::::::::E:T::L:V::AP:Q:::D:::K:ASA:S:::::G::ENA:
NP2236A         :L::::::::::::::::::E::::::::A:P::::L:::Q::::M:D:A:L::::::::
HVO_1475        :L:::S:::::G::::::S:::::::EL:D:::A::TD:A:::::SA:ID:I:::::R::
Hbo0074         :::::T:::::::::::::::::::::::A:::D:::::RI:::T:::IH::::::::A:

consensus       --PLCP--DDPTTVLMNPPFGAQSGNEHADRAFLETAASIADVSYSIHNAGSQEFVEAFA
#oth            11.243324231..1........312221..2..41213214....1..4..42.111.2
HQ1868A         FY:QAIQNS::V::V::::::::H:QK:T:::::T:::R::::::::::S:::S:I:S:V
Hut1221         ::::::::S::V::V:::::::::::::::::::A:::D::S::::::::::AD::::::
hla1773         ::::DV::P::V:::::::::::N::RN:::G::A::SRV:A::::V:::::R:::::::
rrnAC0414       ::::A:P:VEE:::V:::::::::D::::::R:::::::::G:::::::D:::S:::S:T
Hmu1375         ::::R:D:R:G:::V:::::::::::::::::::::T:A::::::::::E::::::GS::
NP2236A         :::VS:::P::::::::::::::::::G::::::::::DV:A::::V:::::ES::::::
HVO_1475        :::::LPD:RQV:::::::::::R::::::::::DSV::V::::::V::E::K::::S:V
Hbo0074         :::::I:::E:::::::::::::H:H::::::::Q::::LSN::::V::T::::::::::

consensus       ADNGGEVTHAFAAEFDLPRQFDFHDEDSRDIDAEVFRIEW-------------
#oth            1.21.32.21142314132..21.234146212.11.12.4222211111111
HQ1868A         ::E::II::::E:S:T:N:::E:::AS:TN::T::Y::N:TDTDITVSNSTEE
Hut1221         :::::T::A:YGSTMS:::::S:::A::KE::V:L:::::QTESS::::::::
hla1773         :::::::::::::D:AIEA:::H:TDA::::::::Y::::A::::::::::::
rrnAC0414       D::::::::::ET:::::::::::ESERQV:T:::Y::D:T::::::::::::
Hmu1375         :::::T::DSYQT::EI:H:::H:EDE::AVT:::Y:V:::::::::::::::
NP2236A         D::A::::::::::::I:::::H:T:Q:ST::T::::::::::::::::::::
HVO_1475        ::A::DL:D::R:T:::D:::::::::R:QL::::::::::::::::::::::
Hbo0074         ::E::::::::R:T:S:D::::::::::K:::T:::::::N::::::::::::