8 genomes BUD1106 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0254 HVO_2742 Hbo2475 Hmu1194 Hut0767 hla1151 NP3670A HQ2881A

Pairwise sequence scores
Consensus score	2748	Hmu1194	rrnAC0254	Hut0767	NP3670A	HQ2881A	hla1151	HVO_2742	Hbo2475
2216	Hmu1194	2768	2271	2080	2080	1882	1969	1998	2010
2309	rrnAC0254	2271	2785	2294	2134	1907	1995	2034	2064
2243	Hut0767	2080	2294	2714	2041	1964	2005	2043	2075
2329	NP3670A	2080	2134	2041	2768	1962	2017	2094	2168
2251	HQ2881A	1882	1907	1964	1962	2822	2061	2178	2217
2270	hla1151	1969	1995	2005	2017	2061	2772	2223	2266
2392	HVO_2742	1998	2034	2043	2094	2178	2223	2785	2484
2469	Hbo2475	2010	2064	2075	2168	2217	2266	2484	2772

366 symbols
consensus       -MSR-A--NREQFRPDDHDNEHFLLTTVVGSYPKPKWLNRARELAEDDDSDFDEDDLEEA
#oth            113233422.2..1.42.2221....1........1.11.131.2122233.243312.1
Hmu1194         ::TG:-::P::::::E::::::::::S::::::::::HD:::::F::P:A::::HNW:::
rrnAC0254       ::TG:-::P:D::K:A::P:D::::::::::::::::HD:::::F::E:A::G::EW::S
Hut0767         :::D:-::T:::::::::::D::::::::::::::E:HD:::::F:AE:TG:::::W::S
NP3670A         MSN:SLPET:A::::K::PT:::::::::::::::::::::K:::::::R:::D::::::
HQ2881A         ::::N:D:::A::::::::SN::::::::::::::::::::ND:VDE:K:T::P:N:T::
hla1151         ::V:NPSA:::::::H::P:DA:::::::::::::::::::D::VD:P::K::VS:::::
HVO_2742        ::::D:E::::::::EA::T:::::::::::::::::::::ND::::P::K:TQEH:H::
Hbo2475         ::::D:S::::::::HG:ES::::::::::::::::::::SK::::::E:K::DE:::::

consensus       HDDAARLITHEHERAGLDTVVDGEMRRNEMVEYFAHRIDGYEFNGPVKVWGHNYFDKPSV
#oth            3...2.1..4..122.1.212......1....1..2111......1.........1...1
Hmu1194         K::::::::Q::::S::::::::::::::::::::EL::::::::R:::::::::::::I
rrnAC0254       K:::S:::::::::::::VIC::::::::::::::::::::::::R::::::::::::::
Hut0767         K:::S:V:::::::::I:V:T::::::::::::::::::::::::R::::::::::::::
NP3670A         L::::::::E::T:::::A::::::::::::::::D::::::::::::::::::::::::
HQ2881A         :::::::::K:::HT::::::::::::E:::::::::VP::::::::::::::::N::::
hla1151         ::::C:::::::::::::::::::::::::::F::D::::::::::::::::::::::::
HVO_2742        ::::C:V::N::::S::::::::::::E::::::::::P:::::::::::::::::::::
Hbo2475         Y:::::V::::::N:::::::::::::E::::::::::P:::::::::::::::::::::

consensus       ADEVEYDEPWLVDEFEFTSDVAERPVKVPITGPYTLARWSFNEAYDSEADLAYDLADLVN
#oth            231.1.112...1.12..241233............13.1...2.2211211.2..1...
Hmu1194         ::::::G:E:::::YK:::S:SD::::::::::::::::A:::::ETTE:A::A::::::
rrnAC0254       ::::::G:Q:::E:::::DE:::::::::::::::::N:::::V::::EQ:::E::::::
Hut0767         VEP::::QQ:::E::K::DE::DV:::::::::::::S:::::::::::E::::::::::
NP3670A         ::::A:::::::::::::TG:T:::::::::::::::S:::::H:EG::E:::E::::::
HQ2881A         TS:::::::::::::N::T:I:N:::::::::::::::::::::::T:E:::::::E:::
hla1151         VE:::::::::::::::::S:::H::::::::::::GF:A:::::P:TEE:V::::::::
HVO_2742        VG::::::::::::::::::::SK:::::::::::::S:::::H:::::::::A::::::
Hbo2475         :S:::::::::::::::::N:::K::::::::::::::::::::::T:::::::::::::

consensus       EEIERLVEAGARYIQIDEPALATTPDDHAIVGECLERIVDGIPEDVRIGLHVCYGDYSRI
#oth            ..123..1..12.1........1112.1.....2..1.1322221..1............
Hmu1194         :::::::D::CK:V::::::::QYE:::::::::::::A::L:::::L::::::::::::
rrnAC0254       ::::A:::::::::::::::::::::::::::::::::::E::D:::L::::::::::::
Hut0767         ::::A::::::::::::::::::::::::::::A::H::EDV:DE::L::::::::::::
NP3670A         :::N::::::C:::::::::::::::::::::::::H:A::::::::L::::::::::::
HQ2881A         ::VS:::D:::::::::::::::::G:Y:::::S::::::D:ST::::::::::::::::
hla1151         ::V:K::::::::::::::::::::E:::::::A:::::S::D:E:::::::::::::::
HVO_2742        ::::Q::::::T:::::::::::::::::::::::::::A:V:DE:::::::::::::::
Hbo2475         ::V:K::::::::V::::::::::::::::::::::::::::::E:::::::::::::::

consensus       YPEINDYPIDEFDLELANGDYEQIDVFKEPEFEKDLALGVVDAHTAEVESVEEIKENIKK
#oth            ...2112.12.1.1..1.1111.131.1222.11.1.1..1.1.2121.1.2...3..33
Hmu1194         :::MLE::VH:Y:::::::::::L::::ND::T::F:M::::::V::::::::::D::::
rrnAC0254       ::::L:::VH:Y:::::::::D:L:::::H::T::F:M::L::::::::::A::::::::
Hut0767         ::::LEF:VE::::::::::F:::G::::H::T::F::::::V:DT:::::A::::::::
NP3670A         ::::L:M:VH:Y:::::::::::L::::::T:::::::::::V::TD::T::::::::I:
HQ2881A         :::::EF::::::V::C:DG::::E::T::A::P::::::::::D:T::T:T:::Q:::R
hla1151         :::::::::::::V::C:::F:::PT:TD::::P:::::::::::::I:::::::A::RQ
HVO_2742        :::L:::::::::V::C::G:::::::TD::::P::::::::V::::::T:::::::::Q
Hbo2475         :::::::::::::V::C::G:::::::TD::::P::::::::V:::::::::::::::LE

consensus       GLEVVPPERLTVSPDCGVKLLPREVAYQKMENMVQAAREIEAELDAGEIDV----DAPGA
#oth            .121....2..1.....2......2.12.11.113.1.11.3.1.2.1.22111146365
Hmu1194         ::::::::Q::::::::I:::::::::G:::::::::::::Q:::E:::::::::VGGQT
rrnAC0254       ::::::::::::::::::::::::::RG:::::::::::::E:::::::::::::V:S::
Hut0767         :::::::::::::::::::::::::::E::A:LTT::::::::::::::::::::--:AC
NP3670A         :F:I::::::::::::::::::::::::::::::E:::QV:K:::::::T:::::GYA:Q
HQ2881A         :::::::::::I:::::L::::::M:RE::A:::::T::::::::::D:AIPAVE:P:I:
hla1151         ::R:::::K::I:::::L::::::I::G:T::::T::::V:::I:S:::::::::EN:LD
HVO_2742        ::K:::::K:::::::::::::::::::::::::K::::V::::::::::L:::::::VP
Hbo2475         ::K:::::K:::::::::::::::::::::::::T::::V:::::::D::L:::::V:TP

consensus       QA----
#oth            533222
Hmu1194         ASAD::
rrnAC0254       E:HADD
Hut0767         E-::::
NP3670A         --::::
HQ2881A         SQADST
hla1151         D-::::
HVO_2742        ::D:::
Hbo2475         ::D:::