8 genomes BUD1120 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0053 HVO_2477 Hbo2376 Hmu1279 Hut1455 hla0938 NP2024A HQ3014A

Pairwise sequence scores
Consensus score	2066	hla0938	HQ3014A	HVO_2477	Hbo2376	Hut1455	NP2024A	rrnAC0053	Hmu1279
1494	hla0938	2427	1107	1313	1269	1182	1254	961	1079
1325	HQ3014A	1107	2092	1137	1426	1142	1095	908	1034
1557	HVO_2477	1313	1137	2125	1375	1231	1215	945	1083
1570	Hbo2376	1269	1426	1375	2099	1276	1166	992	1161
1484	Hut1455	1182	1142	1231	1276	2094	1263	1032	1292
1534	NP2024A	1254	1095	1215	1166	1263	2158	1063	1204
1197	rrnAC0053	961	908	945	992	1032	1063	1749	1232
1387	Hmu1279	1079	1034	1083	1161	1292	1204	1232	2116

338 symbols
consensus       ------------ARRTPAQNAQLALLLEVAGTPKPGNVDRRRDLDDLRFEHFLAGAVGAR
#oth            111113245555763342541311111213321111111142233212313122..1..5
hla0938         ::::::::::::V:PD:VDD:T::::::::::::::::::H:::::::::A::G::::::
HQ3014A         ::::::::MSQTIE:DS:A::::::::D:GSA::::::::DH::SE::M:::F:::I::G
HVO_2477        :::::MVAPVSDRGFG::RH:E::::::::::::::::::::::S::H::Q::T:::::A
Hbo2376         ::::::VTVERSTP::::E::::::::::T::::::::::E::::E:::::::::::::N
Hut1455         ::::::::::::MT::I::Q:E::::::::T:::::::::H::H:::::::::::::::S
NP2024A         MAEESTDSRPAAP::G:::::::::::::::::::::::::::Y::::L:::M::::::M
rrnAC0053       ::::::::::::----------------------------------------M:::::::
Hmu1279         :::::VVPDGGE:V::T::::E::::::::::::::::::EHEYE:::::::::::::::

consensus       EGLRRAA--DG-APVGEAFERAVAGMAAQSGGNTQFGCLLLLVPLVRAAADGD-----LS
#oth            4.1341111312422.51..4111..171311.....2..113..1111363432111.1
hla0938         :::EL::::::ETGI:R::::G::::::R::T::::::::::::::::SVGD:GDDEN::
HQ3014A         ::::Q::::E::SA::T:::::::::SN:A::::::::::::I::::::GVE:MT::::T
HVO_2477        A::EL:E::S::::::::::E:::::SR:G:::::::::::::::::::::D:RD:::::
Hbo2376         R::::::::S::::::V:::::IE::SH::::::::::::::::::::::A:T:::::::
Hut1455         ::::DL:DP:::P:I:V:::Q:::::SD:::::::::G::::A:::::::L:E::::::T
NP2024A         G::AA:::::TTPG:::C:::::::::E::A::::::A::::::::::::TSR::::::T
rrnAC0053       R::D:::::A::D:L:P:::T::E:::G:::::::::A::V:T::AA::S::R:::::::
Hmu1279         P:FE:::::A::D:I:D:::H::E:::Q:R:::::::A::VVT:::AT::S:A:::::::

consensus       PAGVTAVVESTTVADAAGFYRAFEHVDVAVADPPDDADALDVRRGGDAAPALRDRGLTLY
#oth            233234.222.1.2..22...1..1.1...3.1.21232......3112121.3.341.4
hla0938         ::S:DR:TRE:::D::VA::::::::::::::::A:::D::::::::::::::E:DV::R
HQ3014A         S:::RS:::::::::::D:::G::Y:::::E:::EGMA:::::::T::I:T::::DM:::
HVO_2477        :::A:::A::::::::V:::::::::::::G:V::::PD::::::::::E:::N::C:::
Hbo2376         :D:::E:::::::::::D::::::::A:::::::E:LAD::::::S::I::::::ET:::
Hut1455         :ERA:T:A:G:G:E::::::::::::::::::::::M::::::::S::V:EI:E:::S:S
NP2024A         :::TRT:::::::E::C:::::::::::::D:::A:::::::::::::::E::E:A:::A
rrnAC0053       :S::D:::RG:::E:::A::::::::::::D::::GLEP::::::S::I:E::A:ET::F
Hmu1279         REHAS:::AE:::D::::::::::::::::D::::GMEP::::::AEVV:T::::::::A

consensus       DVMALSADR-------------------DGNAAEWTGGFERTFDAAEWILADDGPVPDRA
#oth            ..123.3151111111111111111111.32.4.124..4.2.4113425232..232.2
hla0938         ::::::::PGSLTDSDDPDDSEDSDRVP:R::Q::IE::P:::R:::::QS:G::LT:::
HQ3014A         :::SA:I:-:::::::::::::::::::::::T:::T::::::ET:TA:A::S::L:N:I
HVO_2477        :::::::::::::::::::::::::::::A::R::::::A:::R:::AV:::::::T::V
Hbo2376         ::::A:EG-:::::::::::::::::::::::E::::::S:::::::T:::::::::::V
Hut1455         ::L:R:T:H:::::::::::::::::::::I:R:::S:::::::::DQLVSR:::L::::
NP2024A         ::::::::::::::::::::::::::::::V:::L::::::S:T::S:LSD::::IYQ::
rrnAC0053       :::ES:::I:::::::::::::::::::::V::::VS::::V:K:S::L:DGS:::A:::
Hmu1279         :::ER:::A::::::::::::::::::::DV:::::D::G:V::::DR:ESAS:::A:::

consensus       ARAFLELLAAEPDTLVATNHGRETAREVRRRAQAVLDGA-----------------EDAE
#oth            132.241..331..1.32221322.41155..3.22234111111111111111113433
hla0938         ::::IG:::::::::::A:::P:::::ASE::A:L:G:DRSTSGDIDATAVHDADLDA::
HQ3014A         S:::VTR::QDE::::R:E::SDV:A::KQ::::ARGNP::::::::::::::::::AIA
HVO_2477        :::::D:::E:::::::::::EAV::D:MD::A::S:L::::::::::::::::::-E::
Hbo2376         ::::VD:::EGE::::R::::P:V:A::::::D:ARGDP::::::::::::::::::KVA
Hut1455         :DV:::::::D:::F::I:::E:::::::G::E:ARE:D:::::::::::::::::T:P:
NP2024A         S:T::R:::D::::F:V:RN::AA:E:ATA::::::E:R::::::::::::::::::::D
rrnAC0053       SEV:::::::::::F:::RQD::::V::QE:::::::::::::::::::::::::::T:T
Hmu1279         :TV:::::::R:::F:S:RQD::::L::Q:::::::::E:::::::::::::::::D:VD

consensus       ELAAEFVDEGINPGTTADLVAAALFVALER--GLEV--
#oth            411231.321........23312112..2211.23211
hla0938         ::::A::::::::::::::TC:::Y:::RH:::A::SP
HQ3014A         K:DES::EA::::::::::LV::T:::::QEN:VTI::
HVO_2477        :::D:::A::::::::::I:C::T:::::::::VPL::
Hbo2376         ::::A:::::::::::::I:C::T:::::::::VS:::
Hut1455         T::D:L:A::::::::::ML:GG::::::::::A::::
NP2024A         D:::::::RD::::::::IT:::::I::Q:::::::::
rrnAC0053       G::E:::RRD::::::::::SGS::A::::::::::::
Hmu1279         :F::DL:ERD:::::::::I:GG:::::::::::S:::