8 genomes BUD1124 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC1684 HVO_1551 Hbo3500 Hmu0641 Hut0091 hla2463 NP0634A HQ2669A

Pairwise sequence scores
Consensus score	1146	HQ2669A	Hut0091	rrnAC1684	Hmu0641	NP0634A	hla2463	HVO_1551	Hbo3500
799	HQ2669A	1346	652	672	689	630	652	704	769
908	Hut0091	652	1358	881	933	694	725	697	751
932	rrnAC1684	672	881	1148	924	715	712	726	766
951	Hmu0641	689	933	924	1166	717	695	722	753
808	NP0634A	630	694	715	717	1114	659	679	687
811	hla2463	652	725	712	695	659	1212	641	804
834	HVO_1551	704	697	726	722	679	641	1048	829
914	Hbo3500	769	751	766	753	687	804	829	1174

189 symbols
consensus       --------MEHEATVEGVGVGVDEEG---EGVPAVLLRARDEFLPIFVSSDQAQSIQLAL
#oth            1111111113151315.2.211213111144411.2.41.3152..2114...2113211
HQ2669A         :::::::::N:S:N:A:::::::AN:::::EIS::::A::::Y:::A:TT:::RA:K:::
Hut0091         ::::::::::::::I:::::::G::::::A:A:V::::::EQLI:::::G:::::M:::I
rrnAC1684       :::::::::::D::::::::::S::::::S:T:V::::::E:IV:::::T:::::M:::I
Hmu0641         :::::::::::::::::::I::G::::::P:A:V::::::E:VV:::::::::::M::::
NP0634A         :::::::::A:K:::H:L::S:::DDDSE::P:V:V:H::::A::::I:E:::K::SH::
hla2463         MPPPPRSG:::::E:V:::A:-SAP::::GD::::I:S::G:YV:::::A::::::GM::
HVO_1551        ::::::::-----V:R:I::::G:D::::SN::::V:E::::::::VIT:::::A:::G:
Hbo3500         :::::::::N:R:E:K:I:::::A:::::GS::::I:EV:Q:::::VIT:::::A:::::

consensus       EGEPFERPLTHDLLVEMVTEFGGAIDRVRIDDLADGTFYAKIDAERYEDGERKRMVFDAR
#oth            42.1.2.......2121221..1.1.21.1..1311..21.1.2.1.621233741....
HQ2669A         A:::::::::::::IQ:I:D::::L:G:::::I::::::::::T:::D:::SRHH:::::
Hut0091         :N::::::::::::I:::S:::A::::::::::S:::::::V:::Q:VE:N::NA:::::
rrnAC1684       D::::::::::::::::::::::::::::::::::::::G:::::Q:T:DR::D::::::
Hmu0641         :::::::::::::M::::A:::A::::::::::::::::::::T:Q:L:DR::E::::::
NP0634A         DD:::Q:::::::FI::L:::::::::::::::::S::L::::G:::S::::TTVT::::
hla2463         :::::D:::::::::DIL:::::::::::V:::R:::::::V::::::N::PE:F:::::
HVO_1551        S::Q::::::::::::::::::::::SI:::::SN:::L::V:::::H:::ARSV:::::
Hbo3500         T::::::::::::::D:I::::::::SI:::::T::::F:::::::::N::P:KF:::::

consensus       PSDAIAIALRVDCPILVSDEVLDEAGQPPEAFEQA-------------------------
#oth            ...22.2.2.31.12313.2.2.2..2112512755322212222222222222122212
HQ2669A         ::::::L:V:AE:Q:E:::D:::Y::E::SR::T:SDEEQGIVDPSEFDDYDESDIDTDV
Hut0091         :::G::::::E::::V:N:A:I::::R::::::PDDDEQIGADSDPNPFEDPSFDAGDDF
rrnAC1684       ::::::::::::::VV:T:D:I::::RS::Q:D:SG::::::::::::::::::::::::
Hmu0641         :::G::::::::::LI:::::V:::::::::::E:PEE::::::::::::::::::::::
NP0634A         ::::::V:::::::::IG::::::::::QDT::VR:::::::::::::::::::::::::
hla2463         ::::L:::V:I::::I:::A:I::::R:QDSIRFD:::::::::::::::::::::::::
HVO_1551        ::::::L:I::::::::::::::A:::S::::D--:::::::::::::::::::::::::
Hbo3500         :::SV:L:V:::::::::::::::::::::H:DLGEPS::::::::::::::::::::::

consensus       DGPEDFDL-
#oth            234536441
HQ2669A         :TES:P:GI
Hut0091         :D:::M:F:
rrnAC1684       S:S::LG::
Hmu0641         :DDSE:E::
NP0634A         --------:
hla2463         :::QGGA-:
HVO_1551        ---A:::E:
Hbo3500         :::D:V:::