8 genomes BUD1146 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC3450 HVO_2641 Hbo2201 Hmu2496 Hut0662 hla1652 NP2486A HQ3026A

Pairwise sequence scores
Consensus score	909	Hut0662	NP2486A	rrnAC3450	Hmu2496	HQ3026A	hla1652	HVO_2641	Hbo2201
485	Hut0662	903	373	416	440	357	378	375	359
502	NP2486A	373	936	479	446	339	411	365	372
565	rrnAC3450	416	479	1014	615	376	419	403	397
559	Hmu2496	440	446	615	863	425	428	394	407
571	HQ3026A	357	339	376	425	885	464	455	498
624	hla1652	378	411	419	428	464	954	521	486
635	HVO_2641	375	365	403	394	455	521	1043	560
612	Hbo2201	359	372	397	407	498	486	560	890

147 symbols
consensus       -----------MFERFSSGYYLGRLYVEPYDGDEAAIQREDHERVNEQLYADGEGVERLD
#oth            11122221222...3..21.1..2.....43236111315311321221.3313333141
Hut0662         ::::::::::::::A::GS::::::::::RN:T:P:MS:RQY:T:HR:::----D:DGN:
NP2486A         ::::::::::::::Q:::::::::::::::G::H:VMH:NH::Q::::::------DGKE
rrnAC3450       MYVSVTHTLAP:::Q::R:::::::::::R:DAA::MC::Q::::::::::S:D::::T:
Hmu2496         :::::::::::::::::R:::::::::::SAD:SP:MC::Q:::::R:::T::::I::T:
HQ3026A         ::::::::::::::S::GS::::K:::::TNR:LP:::QD::::M:A:::G:-D::I:V:
hla1652         :::MTDITMHS::::::::::::E:::::HG:ER:V:::V:::H::::::::::::::::
HVO_2641        ::::::::::::::::::S:F:::::::::::A::::H:TE:::L::CV:T::R::::V:
Hbo2201         ::::::::::::::Q::::::::::::::::::VP:::::::TH:::R:::E-:ELV:::

consensus       APLVMKLDTAHFPVHGDEDVPAGTLAVPEDILDDD-L-NPPDLREVLLAKADRARQLLRY
#oth            4...1.2134.31.513251.32.132.434344451311.3333.11.2211.431145
Hut0662         Q:::::::QR::::T:V:S:::D:::::PE::S:SRVE:::S:::::::T:::::PAAVT
NP2486A         ::::::IGS::V:::SAD:::GR:VGL::SA:SAAGVE:::T:Q::::::::::K:::GL
rrnAC3450       Y::::::GSQ::A:::::Q:::D::V:::PM:E:ANVR:::S:E::F:::::H:A:::SI
Hmu2496         R:::V::G:R:LA:E:::T:::D:::::::V:AEVDVA:::T:Q::::::::::::::SM
HQ3026A         ::::::I::G:L::L::TS::T:::S::QS:N:G::::--:AE:N::V::S::::E::Q:
hla1652         ::::::VGGG:I::S::D:::S::::I:HE:A::T:::--::R:N::::D::::ET:::W
HVO_2641        Y:::::::::::::V::DG::S::::L:R:AV:S:A::--::D:P::::D:P::AE::::
Hbo2201         I:::::::QE::::V:N:NI:S::::L:::FAGS::::--::DKS:::::P:::TE::::

consensus       A-GYRPD-------GDAA---------
#oth            432344611111115343312122222
Hut0662         HRRW::T::::::::GSE:::::::::
NP2486A         :PDSPAR:::::::P:G:ADGPAGF::
rrnAC3450       SE:TPTL:::::::P:T:V::::::::
Hmu2496         T::TAF-:::::::----:::::::::
HQ3026A         :::::FG:::::::D::::::::::VT
hla1652         E::WE:F:::::::AN:-:::::::::
HVO_2641        ::::D::DLAPGGP:GSDPDRPDDRLA
Hbo2201         ::::DL::::::::NG:::::::::LA