[L] (Nth) COG0177 Predicted EndoIII-related endonuclease 7 genomes BUD1171 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0398 rrnAC1908 HVO_0878 Hbo0661 Hmu0787 Hut0359 - NP4064A -

Pairwise sequence scores
Consensus score	2058	HVO_0878	VNG0398	Hut0359	rrnAC1908	Hmu0787	Hbo0661	NP4064A
1487	HVO_0878	2063	1290	1290	1384	1378	1449	1332
1605	VNG0398	1290	2038	1380	1440	1429	1400	1431
1598	Hut0359	1290	1380	2105	1497	1422	1442	1411
1755	rrnAC1908	1384	1440	1497	2152	1582	1527	1523
1679	Hmu0787	1378	1429	1422	1582	2083	1444	1499
1700	Hbo0661	1449	1400	1442	1527	1444	2138	1517
1704	NP4064A	1332	1431	1411	1523	1499	1517	2058

284 symbols
consensus       --MDAEPAENISGGDAGGGAAATFEPADADT--RAEAVVDRLGELYWQKAYGGRDAFECL
#oth            12323..21..1.1431114433.323324.111.14...1..22..2.1...1211...
HVO_0878        :::PD:::::::::AS:::RETA:D:::PE:AT:::V:::::::R::R:::::QGG::::
VNG0398         :::AD::::::A:::DS--RPT::ASGADP:::Q:AL::::::::::::T::::A:::::
Hut0359         MSE::::V::::::PGS::SMD::::S::::::::AK::::::::::::T:::Q::::::
rrnAC1908       :MT:K:::::::::T::::QS:::D:ET:G::::::T:::::::M::T:T::::::Y:::
Hmu0787         MSD::::SV:::::ES:::::VE::::::E:::::::::::::::::T::::::::::::
Hbo0661         :::PE::::::::::::::T::E:V::E::::::::::::E::QM::::::::Q::::::
NP4064A         :::AE::SV::::S::::::::D::A:T:A::::::::::E::DR::::::::::G::::

consensus       VRTILSQNTSDKASQPAHDALMARYGG----------A-GDLAAALADADQPELAETISS
#oth            ...1.......2.......3.131.221222222213354..132..1.11541111.33
HVO_0878        :::::::::::::::::::E:::Q:D:::::::::::-:::::ES::A::REGIV:A:R:
VNG0398         :::V::::::::::::::::::Q:::A:::::::::::AD:::::::::::DV::D:::M
Hut0359         :::::::::::V::::::::::D:::S:::::::EDEEEV::VD:::::E:A:::::::G
rrnAC1908       :::::::::::::::::::D:::::::GEDANSEGDIDST:::R::::::::::::::::
Hmu0787         ::::::::::::::::::::::E:::A::::::::::DGE::::T::::::QR:::::QP
Hbo0661         :::::::::::V:::::::S::D::A:GDGDSADGDS:D::::::::::E:S::::::A:
NP4064A         :::V:::::::T:::::::::LE::::::::::::::-::::::::::::::T::::::G

consensus       AGLYNQKSERIIALAERVCEEYGGADGFDAFVREEDPDAVRETLLDMNGVGPKTADCVLL
#oth            1..1....331233.3213131.2212..31.2232133..42..223............
HVO_0878        G:::::::KL:QGV::E:LADF:SEAD::RY::::A:AT::DR::E:K::::::::::::
VNG0398         ::::::::AT::RI:D::::::::::::::::::G::::::AA::::T::::::::::::
Hut0359         ::::::::A:::EI:Q:IR:::::E:D::::::::PAE:::::::A::::::::::::::
rrnAC1908       :::::::::::::::Q:I::::::EA:::::::DS::E:::S::::::::::::::::::
Hmu0787         :::H:::::T:VR::G:::::::FGAE::::::GG::GD::SA::::K::::::::::::
Hbo0661         :::::::::M::GA:::I::SF:::::::E::KD::::T::KR:::IH::::::::::::
NP4064A         ::::::::T:L:::::F:V:T::::::::G::T:AP::E::::::EL:::::::::::::

consensus       FAGGRGGVFPVDTHVHRIARRMGLAPADADHEAVRAALEADVPAEKCGFGHTAMIQFGRE
#oth            .1..12............2..2.1.112....3..23..321.321.......2......
HVO_0878        :::::::::::::::::::::I::::::::::G::::::R:I:D::::::::::::::::
VNG0398         ::::AP:::::::::::::::::I:::A::::::::::::A::DAA::::::::::::::
Hut0359         :::::D::::::::::::Y::L:I::PG:::::::EV::KK::EG::::::::S::::::
rrnAC1908       ::::::::::::::::::::::::::::::::T:::Y::R::::A::::::::I::::::
Hmu0787         ::::::::::::::::::::::::::::::::G::::::D:I::::::::::::::::::
Hbo0661         :S::::::::::::::::G::::::S::::::D::EH:::::::::::::::::::::::
NP4064A         :S:::D:::::::::::::::::::::::::::::S:::::::G::::::::::::::::

consensus       YCSARKPACLDDPEACPLADHCDRVGVDPAAGDVVDPAEADE--
#oth            1.2..2.....1.2...1224.122.1322434.2..1223221
HVO_0878        F:K::::::::G:::::MT:V::M::::A::QS:T:::A::D::
VNG0398         ::T::D:::::::A:::::E::::::::A:T:A:::::D::-::
Hut0359         :::::E:::::G::::::Y:L:::::IE::S::::::::TV:R:
rrnAC1908       :::::::::::::D:::::G:::QI::Y:::D:::::S:TA-::
Hmu0787         ::::::::::::::::::::Q:EQL::S::T:E:F::::RA:::
Hbo0661         ::K::::::::G::::::Y:L:::::::EVEET::::::::-::
NP4064A         ::T:::::::::::::::::R::Q:::Y:ER:E:::::D:P:IE