[C] (CyoA) COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 7 genomes BUD1216 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2195 rrnAC1153 HVO_0944 Hbo2895 Hmu3313 - hla0867 NP2964A -

Pairwise sequence scores
Consensus score	1311	rrnAC1153	VNG2195	Hmu3313	hla0867	NP2964A	HVO_0944	Hbo2895
880	rrnAC1153	1447	576	733	683	687	744	766
715	VNG2195	576	1142	648	488	545	614	609
892	Hmu3313	733	648	1327	645	632	728	810
856	hla0867	683	488	645	1292	720	796	745
922	NP2964A	687	545	632	720	1319	805	800
1039	HVO_0944	744	614	728	796	805	1376	941
1040	Hbo2895	766	609	810	745	800	941	1319

194 symbols
consensus       MEIHAYEKIWLAAALLLIVGFIATITYGAVGAGIAMVDDEGGQVDPDAL---DAHPNFRD
#oth            14214212411342321133222223112214133.122322212354211123434141
rrnAC1153       :QV:RF::V::G:::::::::::::A::S::V:VG::::S:::ISAE:VQNGNTGTQ:D:
VNG2195         -----------------------------------::G:D::T:N::NP:::T:AD::::
Hmu3313         :HV:RF:R:::VGS::::AL:V::V::::::::YG:::A::::::GTDP:::T:SE:V:E
hla0867         :H::::::::::VSV:::LFL:GSV::::::P:V:::S:TEPAI:SGG:::::EDER:SE
NP2964A         :N::T:::F:::::MV::::::::::::S::I::::::::QDT:N::N:::::E::G:A:
HVO_0944        ::::::::L:::L::V::::::G::::::A::::E:I:::::T:::AT:::::Q::K:G:
Hbo2895         ::::K:::::::G:::::::::::VS::::::::E:I:N:::::::K::::::Q::K:SE

consensus       PGVEQTGEN-EYDVYVVARQFAFVPGTSE-PIRVPANSTVTFHVTSADVIHGFEVVGTNA
#oth            .1223322114.311121211415.13511133...222...2..13..3.1112.1..2
rrnAC1153       :::V::::D:K:T::::::::Q::::SGDN:VQ:::GAN:::R::::::V:::S::E::I
VNG2195         :::Y:ADDD:S:::::E::::::S::::::::::::DTN:::::::G::T::::L::::V
Hmu3313         :::YNGS:DGH:::::ETQR:L:::::N::::::::::::::::::R::L::::I::::I
hla0867         :R:::V::::::AA:::::::T:Q:---D:::V:::::::::Y:::::::::::::::::
NP2964A         :::::V::::::E:HII:V:Y:YF::DF::---:::D:E:::::::E::::S:S::::::
HVO_0944        ::I:R:::::S::::::::::V:E:::T:::L::::G::::::::A::::::::::::::
Hbo2895         ::TYK::P::Q:::::::Q:::YL::::D:::::::::E:::::::R:::::Y:I:::::

consensus       NTMVIPGQVSELTVEF---DEPGEYGILCNEYCGAGHHAMEGKIEVVPQDEFNERQEVQ-
#oth            .1.21..1113311421112.1511112.1....21..3.11234.1224.235654553
rrnAC1153       :::::::::::VSAR::::N:::T::LI:H:::::A::T:G:SV::::PE:YDMQ::NID
VNG2195         :::::::::AQ:::N::::::ARTHH:V:H::::PA::::::S::::::S::TPP:QAAA
Hmu3313         :::TV:::KAMV:A::::::::A::::V::::::S:::T:::SLQ:::PS::::TS::::
hla0867         :A::V::E::::::KV:::E::Q:::LI::::::::::V::::VN::S:A:YED:TSGGD
NP2964A         :::::::E:AS::::MPDV:::T:::::::::::P:::D::ALMT:::E:::ELEDDE-:
HVO_0944        :::A:::::::F::Q::::E:A::::::::::::S:::V:::::V:ME:G::DSWY:Q:Q
Hbo2895         :::A::::::QM::K::::::AK:::L::::::::A::::::::V:::E::W::SMV:N:

consensus       --------------
#oth            43323332111111
rrnAC1153       QSADDAQAQEEADQ
VNG2195         DQSEVTDT::::::
Hmu3313         ::::::::::::::
hla0867         GE::::::::::::
NP2964A         ::::::::::::::
HVO_0944        AQGEAEN:::::::
Hbo2895         ::::::::::::::