[I] (ERG9) COG1562 Phytoene/squalene synthetase 7 genomes BUD1267 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0680 rrnAC1477 HVO_1139 Hbo0418 Hmu2962 Hut1629 - - HQ2353A

Pairwise sequence scores
Consensus score	2682	Hmu2962	rrnAC1477	VNG0680	Hut1629	HVO_1139	HQ2353A	Hbo0418
1337	Hmu2962	2689	1035	1198	985	1069	1094	1130
1518	rrnAC1477	1035	3145	1502	1197	1217	1233	1247
1740	VNG0680	1198	1502	2991	1312	1411	1360	1412
1721	Hut1629	985	1197	1312	2663	1469	1452	1541
2025	HVO_1139	1069	1217	1411	1469	2724	1790	2008
2081	HQ2353A	1094	1233	1360	1452	1790	2709	2082
2191	Hbo0418	1130	1247	1412	1541	2008	2082	2705

427 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111112111121222222221212222221122222222222
Hmu2962         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1477       MIAARTVSTNIAVSRVFTVASSQSLCRSYLKIGSDTRESVGTPNRDRDGTDAVAVPFLSS
VNG0680         :::::::::::::::::::::::MLCRSALYCWHPGTPSRGAMIAVGDGSTPQPLLYSPT
Hut1629         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1139        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2353A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0418         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------MMGQQDHRPRA--DDLEWCHEAVQGVSRTFALTVDVLDEPMASYICLGYLLCRI
#oth            21211225453354243345.23.1231.13.....1.1123.2...235113...1..2
Hmu2962         :::::::T:VPQQATL:::::RT:AF::::S:::::::S:EL:::::TEWV:T::::::T
rrnAC1477       YALPRMSGMS:N:TD:SSSE:I:::YD::HR:::::S::ISE:N::::RD:::::::::V
VNG0680         LARPRV:D:R:S:Q:T:::S:R::::S:::D::::::::I:A:E::::TR::V::::::V
Hut1629         ::::::---MNSGH:P-::P:I:::Y::::::::::::::EA:::::::Q:G:::::::V
HVO_1139        :::::::SRHA:A::P:TD:::D:::D::::::::::::::::::::::H::I:::::::
HQ2353A         ::::::-:S:::DH::VDQA::R:::RS:::::::::::::::::::S::::::::V:::
Hbo0418         ::::::-:S:::E::QVDRT:::::::::::::::::::::::::::S::::V:::V:::

consensus       ADTIEDASHIPPDEQAELLETYDAALDPDNDTTVAEFVSAVEPHL-PE-ERNDDWRVVAN
#oth            ...1..23422253124..311113.2224221243.53..32231.322632..4.133
Hmu2962         ::::::EPT::MGRR::::::F::M:AEESE:::ED:L:::::ET::A:DGG:::A:LGQ
rrnAC1477       :::::::G:L::AV:T:::Q::SRS:E:SSG:::SS:HD:::EWI::T:TT:A::E::E:
VNG0680         :::V:::TAM::T:::Q::::::::::::CG::::::QA::GD:V::S::P:A:::::::
Hut1629         :::::::G:::::::VS::A:::::::::A:G:MLD:R:::D:W::::P::SE::::::R
HVO_1139        :::V::S:S:A:::::H::RL::R:::S:D::::D:::A::Q:::P::G:QS:::M::::
HQ2353A         ::::::::::SSET::::::::::::::E:EIDA:T:A:::::::::TG:LD:::T::R:
Hbo0418         :::V::::R:S:P:::D::R::::V:::::::::E:::T:::::::::::M:::::::RD

consensus       APRVVRTFESLPDDVRAAIRPPVRELVDGMADFVDRYADTGGLRIQSREELEEYCWYAAG
#oth            14114331452124235223222..113..1411411322....13233..1...2.1..
Hmu2962         TD:I::LWR:F::P:QDGM:SIT::MAT::::ILR:HE:S::::LETLD::::::::V::
rrnAC1477       :G:I:DV:HT:D:HSTQT::G::::::::::M:::::::A:::::KTLD:::::::::::
VNG0680         TT:::SA::::D:AAK:::::T:::MAT:::S::Q::::A:::::::PT::::::::V::
Hut1629         ::T:WA::ADQ:A:A::::V:::::M:::::::LSAH:A:::::LADYA::D:::H::::
HVO_1139        TA::F::::A::E:::E:VT:::::::S:::M::E::SQ::::::::::::::::Y::::
HQ2353A         ::::L:::GG:::E:QR::I::A::::Q::TT:::::S::::::::T::::::::Y::::
Hbo0418         ::::I::::H::E:::N:VT::A::::Q:::L::E::D:::::::::::::::::Y::::

consensus       TVGNLITNLLTRGDAASDRRAQLYETARSFALLLQLVNVAKDVRDDYTEENNVYLPAEWL
#oth            ...4.213.22225244234542312.23.11......11..133.333.2.1...321.
Hmu2962         :::Q:FMK:Q:A-R:DP:DPTPDP:D::A:::::::::I:::::A:WD::H:::::G:::
rrnAC1477       :::T:V:G:VSH-E:TDEQI::ME:N::::::::::::::::AAT:ME::::::::L:L:
VNG0680         :::E:V:E::A:-::P::AA:AMR:N::::::::::::::::::P::E::::::::Q:::
Hut1629         :::M::::::::DGV:QG:SET:::::G:::R:::::::::::HA:FH:::::::::T::
HVO_1139        :::::::::V:::NVD:E::SR::D::EE:G:::::::I::::H::::S::::::::D::
HQ2353A         :::::::::::::SV::E::Q::::::EE:G::::::::S:::Y::::D:D:I:::::::
Hbo0418         :::::::::V::::ISA:::R:::D::EQ:G:::::::IS:::Y::::A:::::::::::

consensus       ADEGVPQEDVVDPEHEDAVASVVRRTADRAASFLDDAQTYLETMPLRD-GNTLAAWAIPF
#oth            223313224133221543333.1411233.431221.131.122.3341.11.2.112.1
Hmu2962         :E:ELDH:A:AE:::ST:::R::G:VV:Q::DYAHG::R::S:V:EG:N:GL:E:T:L:Y
rrnAC1477       HEQ:LDHS::S:TGNV:SLVP:IEQVTE::EGY:::::AW::A::ETR:::::S::::::
VNG0680         D:HDLAP:::A::::AGR:::::E:VT:::RGYVA:::RW::V::TSQ:::::::::V::
Hut1629         :A:N:E::H:LADRNR:::GR::D:::T::RT::::::S:::A:::SH::::::::SV:Y
HVO_1139        D:A:::::E::::::N:RT::::A::::H:K::::::::::::V:::E::::::::::::
HQ2353A         :::D:::DQL:N::::AGA:T::::::SL:G::::::E:::::I:::::::::E::::::
Hbo0418         :A:::::DE::A::::E:AS:::::::EH::::::::::::::V:AT::::::::::V::

consensus       LLAVGTLRELRARPEDALEETD-VKISREEVFAVVAEMAGDTDRDALAELRERIAAQPYH
#oth            ..11..2...3311311233321..22.2..21144334233413324331251342121
Hmu2962         :::L::I::::E:TV::V:QP:A::LE::::E:LF::AEDGFT::QVRD:AATVR:G:::
rrnAC1477       ::::::I::::E::A:VI:QGN:::::::::HS:TQQFG::N:-PSIG:::AK:RQ::L:
VNG0680         ::::::M:::GN::A:VVR:G::::VD::::H::IGLV:D:F::S:IDSV:::::TESLS
Hut1629         ::S::::::::N::G:::T::G:::VD:::::::MS-V:S::G::::GD::TS:ERE:F:
HVO_1139        ::::::::::V:N::H:VTGEG::::::Q::::::S::N:ASS-ES:::M::I:SR::F:
HQ2353A         ::::::::::LS::::::S::::::::::::::::E::S:T::::V:NR::T:::EE:::
Hbo0418         ::S:::::::L:::::::SK:G:::V::K:::::::::S:::N::::::I::Q:::::::

consensus       RA-T---
#oth            4432221
Hmu2962         EQ:-:::
rrnAC1477       QY:-:::
VNG0680         --:-:::
Hut1629         L:VE:::
HVO_1139        ::T:NLD
HQ2353A         :RP:SAD
Hbo0418         ::P:SAD