[J] (GCD2) COG1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family 7 genomes BUD1275 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1452 rrnAC0289 rrnAC1956 HVO_2706 Hbo2427 Hmu1384 - hla0993 - HQ2713A

Pairwise sequence scores
Consensus score	2089	hla0993	rrnAC1956	HQ2713A	HVO_2706	Hbo2427	VNG1452	rrnAC0289	Hmu1384
1389	hla0993	2989	911	1134	1231	1253	1124	1021	1113
1242	rrnAC1956	911	2092	945	1063	998	1036	1262	1119
1482	HQ2713A	1134	945	2049	1393	1483	1092	1174	1178
1571	HVO_2706	1231	1063	1393	2071	1559	1202	1209	1240
1625	Hbo2427	1253	998	1483	1559	2062	1257	1170	1250
1487	VNG1452	1124	1036	1092	1202	1257	2127	1248	1293
1504	rrnAC0289	1021	1262	1174	1209	1170	1248	2100	1397
1519	Hmu1384	1113	1119	1178	1240	1250	1293	1397	2108

405 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
hla0993         MFRCSLLDHWRSICRVHFQSPRRTATAASHLPSRVAGGFAADCQRHFAPRGHRTTSDCKR
rrnAC1956       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2713A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_2706        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2427         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG1452         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0289       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1384         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------MIDETV
#oth            111111111111111111111111111111111111111111111111111111..11.2
hla0993         GLRSRPTRGLLAARRHAPPWTNMYDGSQSVDLIHALSVRQDPGTPLNWDDDSSS::::::
rrnAC1956       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::N:::
HQ2713A         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::I
HVO_2706        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::I
Hbo2427         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::D:I
VNG1452         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::A
rrnAC0289       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1384         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       EEIREMQTHSSSVVAVKAARALADLLDRDYPTVEEFERDLERNSGALRRANPSHASLHNA
#oth            21.31.2.1.1.21....121.42.211134.22313.3111.221.2.1.1...2.311
hla0993         A:::A:R:::T:A:::::T:S:::::::E:V::D:::::::H:A:V:::S:::::A::::
rrnAC1956       RQ:E::E:Q:::IA:::::K::RE:T::ECH:::D:C:VV::::S::Q:::R:::P:YTT
HQ2713A         :::Q:::::::::::::::Q::T::::::HT:I:N::::::::V:::K:::::::::F::
HVO_2706        ::::::::::::::::::T::::E:TE:::A::::::::::::V:::K:::::::::Y::
Hbo2427         ::::::::::::::::::T:::TE:::::HA::::Y:::::::V:::K:::::::::Y::
VNG1452         ::::::R:::::::::::::::EA:::S:::::AAYV:A:::::T::::::::::::VTT
rrnAC0289       :::S:::::::::::::::Q::R::T::E:::::DYL:S:D:::S:::::::::::::TT
Hmu1384         :::S::::::::::::::::::SA:A::EF::T::YV:A:::::S:::::::::::::TT

consensus       QRRIVTRVSDAEADSVDEAKELTEEAIDRVVEDVETGKDRAAARAAETIEDGDTLLTHDY
#oth            23513642511233224212331332133.1351252.53..342364242241211.12
hla0993         M:EVERSIVG-::T::EDG:QRL:DT:::::D:I::A:GE:::N:T:R::::::::V:::
rrnAC1956       :Q::::DLK::DL:::SA:::RLL:T::E::TEI::S:::::E:::TL:D:::V:V::EN
HQ2713A         MQT:KIN:V:-RKSDL::::K:L::V:H::::::TE::S::::K::P:L:TDS:I:::::
HVO_2706        LQDVLHS:QG-:::DL:::R:::LST::::::T:::::RH::QQ::A:::::Q:F:::::
Hbo2427         MEGVL:::TG-::ST:::::::::S:VE:::::I:N::S::::N::K:FK::E:F:::::
VNG1452         ::EV:S::R::DPA:IP::Q:V:AA:::D::AR:NM::HD:::AT::H:T::Q:::::::
rrnAC0289       :H:::NT:::::P:D:AA:::::N::::D:IDS::SS::::::::VSE:A:D:V:::::F
Hmu1384         ::A::E:::G:DL:::AD::AE::A::QA:::Q::A::E:::K:CGDRLDPTA:::::::

consensus       SSTVLEAIERAAADG---AHLTVYVTEARPRFLGRKTARALAGIDRVDPHLIVDGAAGHF
#oth            .2..212225.452211154243111.1..13...142.7114223212213..1.3.43
hla0993         :T:::::::N::R::::::::::::::::::T:::::::V::::A:::TRMV::S:M:YA
rrnAC1956       ::::MATLMA:LD:::::KEFHL:AS:S::H::::R:::Q::DR:GA:VT::::::V::Y
HQ2713A         :::::::::::TSTK:::TS:K:::::::::Y::::A::R::ELMQ:E:::L::S:::S:
HVO_2706        ::::M::V:L:V:::::::Q::A:::::::::::::F::E::A::D:E:::M::::S:M:
Hbo2427         :::::::V:I::::::::N:M:T::::::::Y:::::::T:S::::IE::::::::::I:
VNG1452         :::::::::L::Q::::::::D:F:::::::H:::::V::::QL:::::T:::::::::V
rrnAC0289       :::::A::DD:IEA::::HSFE:::::S::::::::MT:H:SDR:G::VT::::S:::::
Hmu1384         :A::I:S::::IETADGEVDM::::::::::Y::::L::SM::::G::VR::::S::::Y

consensus       LSECDRVLVGMDCIVDDTLYNRIGTFPIVAAAADLDVPVTVVGSAAKLVDGGFAFENEFR
#oth            1422.2.32.12.223212...1..2.1221.23512...11.241.51333.5.2.22.
hla0993         :RD::Q::L:IT:MTGG:Y::::::::L:VT:RE:G::::A:::D::RIEE-:R::::::
rrnAC1956       :::A:::F:::N:LI::VV::::::L:LA:T:NEM::::::::TSS:FIGS::T:R:T::
HQ2713A         ::D::::V::::::::E:::::V:::::I:T::AV::::::::::::V:::S:V::::Y:
HVO_2706        :PG::::II::::::EE::::::::::L::::NEVG::::::::G::V:::::R::::I:
Hbo2427         :E:::::V:::::::E::::::V:::::::T::Q::I:::::::G::I::D::I::::I:
VNG1452         :DD:::::L::::::A::Y:::V::Y::::::::AGT::::A:::::::AD::Q:T:D::
rrnAC0289       MP:V:::::::::::::::::::::Y::AT::::N::::::::A:::Y:::A::::::I:
Hmu1384         :::::H::::::::::::::::V::Y::A:::::QG::::::::ES::I:::::::::::

consensus       SPSEVMREPVEGFEIENPAYDATPTRLLDTVITDDGVR-EF----
#oth            3521.31..3212522..2.....2512.411.121251322211
hla0993         DAV::::::::DVT::::S:::::IGM:::I:::::IV::-::::
rrnAC1956       QG:D::L::P:::D:G::G::::::S:::::V:E::IL:Q:::::
HQ2713A         ::A::SL::L:DIM::::::::::VS:I:Q::::N::E:S:::::
HVO_2706        ::::::L:::::I:L:::::::::VD:I:E::::E::I:::::::
Hbo2427         :TA::SL::::DVF:::::::::::E:V:E::::E::::T:::::
VNG1452         DT:::I:::PA::TV::::::::::::::A:V:E::R:T::PLES
rrnAC0289       PL:::L:::AD:::VA:::::::::H:::::V:::::H::Y::::
Hmu1384         :V:::::::A:::S:::::::::::::::N:V::ER:V::YDE::