[FR] (SsnA) COG0402 Cytosine deaminase and related metal-dependent hydrolases 7 genomes BUD1277 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1205 pNG7229 HVO_2929 Hbo2354 Hmu1785 - hla1068 - HQ2049A

Pairwise sequence scores
Consensus score	3326	Hmu1785	VNG1205	HQ2049A	pNG7229	hla1068	Hbo2354	HVO_2929
2500	Hmu1785	3306	2122	2084	2240	2277	2213	2322
2526	VNG1205	2122	3276	2055	2244	2266	2195	2343
2559	HQ2049A	2084	2055	3367	2543	2114	2323	2266
2758	pNG7229	2240	2244	2543	3352	2259	2446	2491
2629	hla1068	2277	2266	2114	2259	3326	2316	2467
2657	Hbo2354	2213	2195	2323	2446	2316	3290	2478
2853	HVO_2929	2322	2343	2266	2491	2467	2478	3325

448 symbols
consensus       --MLLAGTVVADAETVIQDGAVVVEGDRIVAVGDRADLTDAYPDHERRDFDILAPGLVGG
#oth            1112221111312211231....13122.5...22252532111.242331223..11.2
Hmu1785         :::R:T:::::::D::YE:::::TS::E:::::::QR:VRQ::::DS:S:::V::::::S
VNG1205         MTL:T:D:::Q::DR:L:::::::VD:::T::::::A:A::H:::::I:V:V:::::::A
HQ2049A         :::K:S:DI:QNSSRI:P:::::::DTE:I:::::E:ICEQ::::PEQHY::IM::M:::
pNG7229         :::::T::::S:S:::L:::::::S::::E:::S::E:ESQ:A:::HQSY:V:L::::::
hla1068         ::::I::::I::P::::P::::::::ET:A::::AEI:RE:::::::::I::V:::::::
Hbo2354         :::::S:::I:NS::::A::::::VD:::R:::::ETV:::H::::V:E::L:I:::I::
HVO_2929        ::::::::::V::S:I:EE:::::D::::::::AH:::::R::N::::E:G:V:::::::

consensus       HVHSVQSLGRGIADDTELLDWLFDHVLPMEAALDAEEMRAAAELGYLECIESGTTTVVDH
#oth            .1..........1..31.1...1.21.....311.43113..3.1.1.3211.1.121..
Hmu1785         :::::::::::::::EA:::::::::::::::M:::Q::T::T:::M::LA::V::::::
VNG1205         :::::::::::::::Q:::::::::::::::G:::A::::::D:A:::FV:::::G::::
HQ2049A         :I::::::::::S:::::I:::Y:YI:::::T:T:N::EI::K:::::L::T::::AI::
pNG7229         :I::::::::::::::::::::::YI:::::S:T::::EV::K:::::M:::::::CI::
hla1068         :::::::::::::::AA:::::::A:::::::M::GAT:::::::::::L::::::::::
Hbo2354         ::::::::::::::::A::::::::::::::S:::DG:::::::::::LL:::::::I::
HVO_2929        :::::::::::::::::::::::::::::::G::::G::V::::::::::::::::::::

consensus       LSVAHAEEAFEAAGEIGIRGRLGKVLMDQRSPDGLQEDTDAALAESERLIQRYHGAHDDR
#oth            ...4..23..1..214.1.121...1..421121.2.1.121.1.1.2.1241121411.
Hmu1785         ::::::DQ::::::::::::L:::::::YDA-GA::::::::::::::::E:::::F:::
VNG1205         :::D::G:::G::ADS:V:A::::::::KD:::::::::::::::T:A::REWD::C:G:
HQ2049A         :::::::Q:::::::M::::V:::::::::::G::L:E:QD::::T:Q:::K::RS::::
pNG7229         ::::::DR::::::::::::V::::::::::::::L:::Q:::D:::::::Q::::YN::
hla1068         :::N:::::::::I:T:::A::::::::RD::E::L:::::::::::A::EE::::A:G:
Hbo2354         :::S:::T:::::::L:::::::::M::::A::::I::::E::::T:::L:T:::S::::
HVO_2929        :::R:::::::::::M:::::I::::::TNA:E::::::::G::::::::E:::DSF:G:

consensus       IRYAVTPRFAVSCSEACLRGARDLADAYDGVRIHTHASENQDEIETVEADTGMRNIHWLD
#oth            11..1......1.1.2...13.2.1.4111.1........33..2..132..2..12..1
Hmu1785         :::::::::::::T:R:::::::::::::D::::::::::R:::Q:::DR:::::VE:::
VNG1205         :Q::I::::::::T::::::C:A:::E:-::::::::::::G::::::TE::K:::::::
HQ2049A         :::::::::::::T:E:::RT:E::::::::::::::::::N::K:::::::Y:::::::
pNG7229         ::::::::::::::::::::V:E:V:K::::::::::::::S:::::KE:::::::::::
hla1068         V::::::::::T::::::::C:::V:RH:::T::::::::E:::::::::::K::VL:::
Hbo2354         :::::::::::::::E::::::E:::T::D:T::::::::H:::::::E:::::::E::H
HVO_2929        :Q:::::::::T::::::::::::::R:::::::::::::RS::::::DE::::::::::

consensus       EVGLTGEDVVLAHCVWTDESERELLAETGTHVTHCPSSNMKLASGIAPVVDYLDRGINVA
#oth            1.....2..1....11.213..22....1.3.11...........1..151.121.111.
Hmu1785         ::::::P::T:::::::::T::AI::::D:T:V::::::::::::::::EA::Q:::T::
VNG1205         D:::::::::::::::::D:::A::::::::::::::::::::::V:::A::RE::::::
HQ2049A         ::::::::::::::I::N::::::::::::::::::::::::::::::::::::K:::I:
pNG7229         :::::::::::::::::::::::V::::::::::::::::::::::::IW::R:::::::
hla1068         ::::::P::T:::::H:::R:::V::::D:V::::::::::::::::::Q:::::::T::
Hbo2354         :::::::::::::::H:T:A::::::::::N::Y::::::::::::::I:::::::VT::
HVO_2929        ::::::D::::::::H::D:::DV:::::::::Y::::::::::::::IP::::::::::

consensus       LGNDGPPCNNTLDPFTEMRQASLLQKVDALDPTALPAATIFEMATRNGAKAAGFDRVGEL
#oth            1.1..........2.1..1..11.2..241.11321144211...41.12.1..141.41
Hmu1785         :::::::::::::::::::::A::A::GE::A:::::::A:R:::EH:GQ:T:::-::V:
VNG1205         ::T::::::::::G:A::::::::G::::::::::::RSV:::::H::::::::EN::RI
HQ2049A         ::::::::::::::::::K:::V:::::N::::VAAMED::::::I::::::::::L:::
pNG7229         I::::::::::::A::::::::::::::Q::::VT:::E:::::::::::::::EEL:AI
hla1068         ::::::::::::::::::::::::G::::R:::R:::S:VL::::T:::H::::::L:T:
Hbo2354         :::::::::::::::::::::::::::EH:::K:T::QV::::::I::::::::ED::::
HVO_2929        :::::::::::::::::::::::::::::::::ST::::V::::::::::::::::::::

consensus       REGWRADIVGLDTDRTRATPLHDPLSHLVFAAHGDDVRFTMVDGNVLYDD--GEHVRADA
#oth            21.23..211131.41.2..21.21.1..11.1.1..31...2.31212311.43344.1
Hmu1785         AP:RP::VI::A::TA::::V:::::::::::::::::::::::E:V::::::SFANV:G
VNG1205         A:::T::L:::S::AA:S::I:::Y::::Y:::::::TL:::A:D:::R::::A:::M::
HQ2049A         KP::::::I::S::T::G:::Y:V::Y:::::R:N::E::::N::I:MEN:::TVTI:::
pNG7229         ::::::::::::::L::::::::V:::::::::::::::::::::::MEQ::::VTTI::
hla1068         :::Q:::VI:IT:::::::::::::::::Y:::::::V::::::RIR:::::::::GI::
Hbo2354         ::::K::::A::::I::::::::A::::::G::::::E::::::E:V::ETF:GLQTG::
HVO_2929        ::::K:::::I:A::::::::::V:::::::::::::V::::::D::::E::::::::::

consensus       DAIRERA------RDIADARKDAQESK-
#oth            231.53.233232244234354344222
Hmu1785         A:V:AD::::::::RH::SIYAEIS::D
VNG1205         P:::::::::::::EF:AEL-------:
HQ2049A         :S::QS:TDVAESL::S:::A:::DQ:P
pNG7229         ::V:SQ:STMGLEM:LE::::S:::Q:P
hla1068         ::V::::TRHAK::VVEE:GI:TA::-:
Hbo2354         :E::R:::::::::E:EFDG:P:----:
HVO_2929        :G::K:::::::::AV::GLDS:PT:D: