[C] (Tas) COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 7 genomes BUD1278 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0268 rrnAC1858 HVO_0757 Hbo0774 Hmu0814 - hla1810 - HQ1182A

Pairwise sequence scores
Consensus score	2746	VNG0268	HQ1182A	hla1810	rrnAC1858	Hmu0814	HVO_0757	Hbo0774
2035	VNG0268	2739	1560	1621	1813	1729	1601	1688
1972	HQ1182A	1560	3024	1650	1619	1607	1675	1877
2002	hla1810	1621	1650	2790	1672	1620	1767	1834
2138	rrnAC1858	1813	1619	1672	2736	2122	1783	1870
2109	Hmu0814	1729	1607	1620	2122	2756	1725	1802
2142	HVO_0757	1601	1675	1767	1783	1725	2744	1897
2270	Hbo0774	1688	1877	1834	1870	1802	1897	2749

397 symbols
consensus       MATRRATWAYRDRFGDAFARTYFRRFGPGVVSSIGIGTYLGDPTDAVDDRYREAIVAALE
#oth            ...431113.123111311..11..111112..1.2.....211223.322222244112
VNG0268         :::AD::FQ:KQ:::::T:::::::V:DCA:::V:L:::::A::A::::ALY:TVR:G:T
HQ1182A         :::K:G::N::EQ::EE:G:::::::D:::T::::::::::AA::DA:N::YR:L:D:I:
hla1810         ::::E:L:N:::E:::::G:::::::::::A::::L:::::::IP::::AS::::DL::R
rrnAC1858       ::::E:::::::DH-:E::::FY::::D:::::::::::::::::ER:AS:HD:::T:::
Hmu0814         :::QS:::::::DH-:D::::::::::DC::::::V:::::::::EQ:E::::::AD::R
HVO_0757        :::G::::::::::::S:G::FY::::::::::::::::::E:::::::::::SL:S:::
Hbo0774         :::K:G::G:::E::::::::F::::::::::::::::::::::::A:A:::::LT::::

consensus       SGVNVVDTAINYRHQRSERVVGDAVRDADVDRDAVVVATKGGFVPFDGERPDDPGAYVRE
#oth            2.1.22...2...11.1.....212142312.22131.1.1..2...232.21.111123
VNG0268         A::::I:::V::::::::::::R:I::SEIP::::FL:::::::::::AQ::A::E:::R
HQ1182A         ::::HL:::::::C::::::::::IA::A:::::I:L::::::I:::::K:A:::E:IT:
hla1810         ::::H::::V:::CG:A:::::E:::NSPI:::::::::::::L::::::::::A:::::
rrnAC1858       ::I::::::::::::::::::::::A::::::K:IA:::::::I::::A::A::::F::S
Hmu0814         ::I::::::::::::::::::::V::TGP:::ES:L:::::::::::ED:::::::::GS
HVO_0757        H:::L::::S::::G:A:::::::::G:::::::::::S:A::::::R::::::::::::
Hbo0774         ::::L::::::::C::::::::E:L:E::IA:EE::::::::::::::S::E:::::::D

consensus       EFLDTGIVDGDDLARGSHAIAPAYIDAMVDRSLDNLGLDTIDCYYVHNPETQLAVRSREA
#oth            222341321412.13.4.311.2121433.1..421.1.21.1..1.......5322232
VNG0268         ::V:R:V:::::::A:::S:::G::::::::::S:::V::::L::::::::::DE:PAS:
HQ1182A         ::IQN:TL:AAS::::C::LT::F::S:::Q::R:::V:D:::::::::::::T:::QT:
hla1810         R:IEPE::AP::::N:A:::::D:LEWSL::::NR:::::V::::::::::::VT:::::
rrnAC1858       :Y:::::::R:::VA:Q:C:::D:::DQI::::T::::::::L::::::::::K:N::::
Hmu0814         :Y:::::::S:::V::H:C::::F:EDQL::::::::V::::L::::::::::EAN::A:
HVO_0757        TV::A:LA:P:E::H:::T::::FV:E:::::::LT:::HV::::L:::::::::TD::T
Hbo0774         ::VR::::::AE::::::::::G:L::LF:::::::::::V::::::::::::::::::D

consensus       VYDQLEAAFERLERRRAAGDIGHYGVATWEAFRVPADHDSYLSLPEIVARAEAAAETVG-
#oth            ..121111..3..2.32111135....1.4.1..2311231.1.212241.22.131111
VNG0268         :::H:::T:::::Q:V:::::T:::::::::::::::::H::D:G::IS::R:::K::::
HQ1182A         ::E::T::::Q::::C:T::::G::::S:N::::SPS::::::::RV::C:::::D::::
hla1810         ::::::T:::A:::::T:::::A::::::H::::AE:DER::::A:VL::::::G:A::P
rrnAC1858       :::::::T::Q::E:A:::::NQ:::::::::::::::::H:::::::E::R::::::::
Hmu0814         :::::::T:::::::::::::R:::::::D::::::::::::::::::R::QS::A::E:
HVO_0757        :::RV:::::V::::V::D:::R::::::::L::AP:::A::::::L:R:::R:::::::
Hbo0774         ::::::::::V::E::L::EL:V::::::K:::::R::Q:::::::VLT:::R::DAA::

consensus       NDDTGLRAIQLPFNVQMADAFTVEAHRGPE------------------------------
#oth            333221411.1...13.1....23213423111111111111111111111111111112
VNG0268         :TA:H:::::V::::Y:::::::A:QE::D::::::::::::::::::::::::::::::
HQ1182A         V:EC:FM:::::::I::S::::TT::PD:AHRDDTAVQGDTTGIDQNQSIFDNDTNTHTE
hla1810         D::H:FG::::::::A::::::RRNQ:S:G:::::::::::::::::::::::::::::D
rrnAC1858       :AA:H::::::::::A::::::::S:D:A:::::::::::::::::::::::::::::::
Hmu0814         :ET::F:GV:::::::::::::::::E:A:::::::::::::::::::::::::::::::
HVO_0757        :::HS:E::::::::V::::::::::DTDA::::::::::::::::::::::::::::::
Hbo0774         A::C::A:V::::::::::::::::::H::::::::::::::::::::::::::::::::

consensus       --GPQSALWYAHEAGLNVFTSASLAQGDLAAE--IPAAVDAQLAGETPAQRAINFARSAP
#oth            34343.2.22.1.2113121..112..21342211.421235.2.1.21..22..2..1.
VNG0268         ::::::V:::::::::::::::::G::EVVSG::::S:::T::::::::::GV:::::::
HQ1182A         TTTEI:::Q::Q:R:I::IA::T::::::TNGDA::P:::TE:S:::::::::::T::::
hla1810         DSE:V:T:EL::::::S:V::::IG:::::V:GA:::DI::T::::::::::L:::::::
rrnAC1858       :::::::::F::::::D::::::IM::Q::::::L:DD:A:K:S:::S::::::::::::
Hmu0814         :::T:::::F::::E:S::::::IM::E:STG::L:DDIA:R:D:D:SV::S::::::P:
HVO_0757        :GEAM::::::::H::HA:::::::::::::::::::S:NSV:::D:A::::L::S::::
Hbo0774         EDKDV::::::Q::::D::A:::::::::::S::::E:::E::S:::A::::L:::::::

consensus       GVTSALVGTGSPEHVAENVAAGTFEPLGARAFDAVFE
#oth            ...31.1.22131.14..11..111....41..11..
VNG0268         ::::::A::TDAD::T::AD:::::::::N::::I::
HQ1182A         :::T:::::::::::S::::::::D::::Q::::I::
hla1810         ::::S::::SDLD::R::::::::D::::S:::::::
rrnAC1858       :::CS::::::V::AR:::D::RY:::::D:::::::
Hmu0814         ::::::::M::::::V::::::RY:::::S:::::::
HVO_0757        :::A::::AS:V::::::::::::D:::::T::S:::
Hbo0774         :::C:::::::::::::::::::::::::::::::::