[M] (WcaA) COG0463 Glycosyltransferases involved in cell wall biogenesis 7 genomes BUD1315 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2065 rrnAC3518 HVO_0704 Hbo0830 Hmu0989 - - NP1436A HQ1250A

Pairwise sequence scores
Consensus score	1922	HQ1250A	NP1436A	rrnAC3518	HVO_0704	Hbo0830	VNG2065	Hmu0989
1311	HQ1250A	2633	1088	1092	1127	1221	1013	1077
1348	NP1436A	1088	1903	1111	1131	1158	1102	1155
1348	rrnAC3518	1092	1111	1939	1121	1168	1108	1274
1462	HVO_0704	1127	1131	1121	1980	1331	1165	1234
1512	Hbo0830	1221	1158	1168	1331	1990	1145	1292
1371	VNG2065	1013	1102	1108	1165	1145	1927	1230
1486	Hmu0989	1077	1155	1274	1234	1292	1230	1922

357 symbols
consensus       -MMRSVGVVVPAYRPDPERLGSYLQALDEQL--DPAAIRVELDAPRPGVLDAL------A
#oth            1133.2.1.2..12..411.34.25313442112.33211...11433234321111113
HQ1250A         M:T::I:::I:::Q::::::T::::Q::T:VTPS::VL:I:::::SSSL:KQ:YSRLSNS
NP1436A         :-:S:L::::::F:::V::::T:::DIADT:::::VV::::::D:DEATTA:V::::::S
rrnAC3518       ::S::::::L::::::MDQ::T:IA:I:GA:::A:QT:V:::::::D::PVQ:::::::R
HVO_0704        ::SQ::::::::::::::::VP:VH::V:S:::::D:V:::::::::ET::::::::::D
Hbo0830         ::T:::::::::::::S:::AD:VS::RSH:::S::TV:I:::::::::::R::::::::
VNG2065         :-:T:::I:::::D::ID::TA::D::R:TF::::::L::::::AG:::A:RI::::::R
Hmu0989         ::DQ:::I::::F:::VD:::::VRT:::::::A::R::I:::D:E:::TEG::::::::

consensus       DL---PAT--VNTVDTRRGKGAAITAGFEALE--T-------------------------
#oth            3311122322124223.........1...2152211111111111111111111111111
HQ1250A         TF:::T:SVEIAIA:::::::::::::::R:CAC:NTTANSTTTTVTSNNETTERSNIDP
NP1436A         :IGVS:VV:::::::::::::::::D:::::G::::::::::::::::::::::::::::
rrnAC3518       S:::::IE:::H::PY:::::::::::::R::::::::::::::::::::::::::::::
HVO_0704        A::::::VAR::D::A:::::::::::::S:R::::::::::::::::::::::::::::
Hbo0830         ::::::::::::::::::::::::::::::IADDV:::::::::::::::::::::::::
VNG2065         :A:::GV::::AESTG:::::::::::::::D::::::::::::::::::::::::::::
Hmu0989         S:::::::::::A:PY::::::::::::::I:::::::::::::::::::::::::::::

consensus       ---------------------DVLAFADADGSTPAASLATVVAAVRDGDADLAVGSRRHP
#oth            111111111111111111111.22..1....1.21312151233143341.1.1......
HQ1250A         GFDRDTDVTINLTTTPPASTI:I::::::::::::S:FE::LR:LINDT::V:T::::::
NP1436A         ::::::::::::::::::::::R::::::::::G::E:::::::LE:--::V::::::::
rrnAC3518       ::::::::::::::::::::::::::V:::::::VN::ERILDP:I:SRT::::::::::
HVO_0704        ::::::::::::::::::::::I::::::::::::::M:D::::::::-:::::::::::
Hbo0830         :::::::::::::::::::::::::::::::::::::F:S::KS:AG:::::::::::::
VNG2065         :::::::::::::::::::::::V:::::::A:::G:::E:::R:T::::::::::::::
Hmu0989         :::::::::::::::::::::::R:::::::::D:::::H:IDR::A:E:::::::::::

consensus       DATVASHQTFARRLLGDGFAWLARRLLDVRLYDYQCGAKAITAAAWEAVRDHLYEAGFAW
#oth            412.33...22..3.......2.13.1226.1........22221.43..4.1122....
HQ1250A         S:D:TA:::LG::Y::::::::::::::EQ::::::::::::TD::Q:::S:I:AS::::
NP1436A         ESA::G:::L:::::::::::::::::A:G::::::::::LS:E::S:::::IH:P::::
rrnAC3518       :::::T:::::::F:::::::::GQ:::A::::::::::::DV::::R:::::::P::::
HVO_0704        N::::::::V:::Y::::::::::H:TE:P::::::::::V:::::ND::T::::P::::
Hbo0830         ASD::::::::::R:::::::M:::::::H::::::::::L:TE::R:::P:I:::::::
VNG2065         ::::E::::VV::::::::::::GT::A:D:H::::::::L::::::R::E:::::::::
Hmu0989         ::::S::::::::F:::::::I:GH::::S:::::::::::::EG::H::T:::D:::::

consensus       DIELIAVAGALGLRVAEVPIRWEDQPGSTVSPVRTSLRLARALLRARHRAKRLRDDRLHA
#oth            .1..2.1211224212...13...2.1...112113351232.231...114143121.3
HQ1250A         ::::L:IS:G::YQ:::::V::::::::::::L::A:::G:V:VT:::::RA:AH:PV:R
NP1436A         ::::L:::A:ME::IR::::::::K:::::A::::T:SML:::FV::::::::QNSGV:R
rrnAC3518       :V::::I:A::D::IE::::E:::K:::::::I:::ID:LE:::T::::S:Q:::::::T
HVO_0704        :::::::S::F:H::::::VV:::::N::::::D:TVKM::G:::S::::RTI:E::::E
Hbo0830         ::::::::::::E:I::::V::::R::::::::D::Y::::::FSS::::RLI:E::::T
VNG2065         :V::V::G::::C:::::::T::::::::::T::APVG:LG::V:::::::::G:S::::
Hmu0989         :V::V:I::::::T::::::E:::R::::::::::::NM:T::::::::::::S:S::::

consensus       ALAA-------------TRSDPPALIER------DDE--------------------
#oth            213311111111111114323321.21343333354211111111111111111111
HQ1250A         L::SIERSSSQPVIDSVAT:K:T::S:KATNITI:A:AEADVNVNIDTTDQSSIEVG
NP1436A         L:GV:::::::::::::-GE::::::D:::::::EER::::::::::::::::::::
rrnAC3518       :::E:::::::::::::HFDE:T::::-::::::K:R::::::::::::::::::::
HVO_0704        LID::::::::::::::-:::ERT:V:QFSTEVA::-::::::::::::::::::::
Hbo0830         FIES:::::::::::::::DHE:::V::LGEALDTS:::::::::::::::::::::
VNG2065         :::::::::::::::::RG::DR:::D:PG::::SH:::::::::::::::::::::
Hmu0989         :I:::::::::::::::::EEG::::D-::::::N::::::::::::::::::::::