[R] (-) COG1011 Predicted hydrolase (HAD superfamily) 7 genomes BUD1341 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1577 - HVO_0586 Hbo0935 Hmu0507 - hla2657 NP5310A HQ1412A

Pairwise sequence scores
Consensus score	1544	HQ1412A	Hmu0507	VNG1577	NP5310A	hla2657	HVO_0586	Hbo0935
999	HQ1412A	1623	668	573	795	875	844	873
856	Hmu0507	668	1621	547	764	689	732	710
764	VNG1577	573	547	1125	591	637	562	578
1183	NP5310A	795	764	591	1548	1005	933	967
1160	hla2657	875	689	637	1005	1561	1021	976
1162	HVO_0586	844	732	562	933	1021	1603	1095
1186	Hbo0935	873	710	578	967	976	1095	1650

219 symbols
consensus       VAVTFDLFGTLVDVERPADPAAAVAAELRARGVAVPDDWEAAYREVHIDAPRGAEVPLPA
#oth            222311212111323313213321142145221311222441133514233412.21.22
HQ1412A         M:::::::D:::T:S::::::::::S::QT:::T::S:::T:::T::VESQ::S::::ST
Hmu0507         :V:S::C::::::AD::EE:W::::DA:A::D:T::S:::::::SS:REYE::::A::DE
VNG1577         -----------------------------------------------------M:RS:S:
NP5310A         M::A::::::::::DT:::::E::::::E:::::::SAFG:::::Q:T:::E::::::::
hla2657         :::::::::::::::Y:S:::EI::R::ES:::E:::::HV::G:R:V:::A::::::::
HVO_0586        :::::::::::::A:Y:S::GS:::DA::EY::::::::DD::::::::::E::::::::
Hbo0935         ::IS::::::::A::::::::::::::::D:::::::::GD::A:L:::::D::::::::

consensus       HVAAALASRGVDAPANAARRAVVAAFDPDVTTRPGAVAAVAAAAERGPVGLLSNCSVPEL
#oth            .1331.3111.233423213.131..123.22121154.1331324.1.121...1.12.
HQ1412A         :IN:::E::D:S:::EYI:H::T:::::T:Q:::N:IT::ET:VAN::::I::::::SQ:
Hmu0507         ::RL::::::::IEGE::HD:TL::::SP::V:D::RI:L:S:R:Y:::AVC::::::G:
VNG1577         :::D::E::::E::SDTV:A:TL:::ETP:QR::::A:::E::::::::AV:::::::G:
NP5310A         ::::V::AHD:EVTN:::::::::::::::RV:::VS::L:::S:::::::C::::::::
hla2657         :::H::D::::E:AD:VV:H:::::::::::R:D::LE::RDVSDQ:::::::::A::::
HVO_0586        ::::::R:::::S:D:::::::IT::::E::::::::D:::::R:A:A::::::::::::
Hbo0935         ::S:::R::D::::::::::::::::::E:R:PE:::D::S::::::::A::::::::::

consensus       VARTLIRADL-RDAFDAVVTSVGCGWRKPHPNAFEAVADALGVAPEELVHVGDDPETDGG
#oth            1411.4111112451.3211.12.......252.233.43.3123331211..1131...
HQ1412A         :H:::M:S:ID:SL:::I::::D::::::::R::Q:::KS:R:D:TS:I:I::N::::::
Hmu0507         :E:::D:::::--:V:S::::::::::::::TI::RT:A::A:PLD::::::::AR::::
VNG1577         AE:A:SQ:G::A:R::::::::::::::::A:::Q::::::DAP::T:::I:::::A:::
NP5310A         :G:::V::::::GT::::::::::::::::::S:GEL:::::::V:DI:F:::::D::::
hla2657         :PK:::::G:::GE::::T::I:::::::::K::::A:K::::::AS:::::::::::::
HVO_0586        :::::::S::D:RG::DIT:::A:::::::RQ::::A:RG:::DAA::L::::::DA:::
Hbo0935         :::::::S::D:::::VM:S::A::::::::E:::T::GR:D::::T::::::::N::::

consensus       IEAVGGRFVDLTETPLDALPAALDAAE------------
#oth            232..13123232141432334.3335223233322321
HQ1412A         :ND:::H:HNI:K:S:GQIST:::GEFNNNDSNIN::::
Hmu0507         ADR::ATALV:DDVA:S:V:EW:A::V::ADAASGEEPP
VNG1577         :T:::::A:L::::::Q:V:::::D:-::::::::::::
NP5310A         ::::::::::VSD:::S:::EQ:::D:::::::::::::
hla2657         V:::::::::V::::::::A:Q:E:EL::::::::::::
HVO_0586        :::::::::N:R::T:ESVA:R:R:G:::::::::DPCP
Hbo0935         V:::::A:::VR:VGF:T:TDS:RRGARSELLSEGESCP