7 genomes BUD1343 10 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC2772 rrnAC3457 HVO_1564 Hbo3487 Hmu2492 Hmu2859 - hla2444 NP1074A HQ2660A HQ3028A

Pairwise sequence scores
Consensus score	3875	NP1074A	rrnAC2772	Hmu2859	hla2444	HQ2660A	HVO_1564	Hbo3487	HQ3028A	rrnAC3457	Hmu2492
2742	NP1074A	3853	2502	2576	2224	2275	2344	2361	1251	1379	1356
2694	rrnAC2772	2502	4180	2901	2165	2204	2201	2247	1146	1407	1344
2785	Hmu2859	2576	2901	3928	2250	2229	2273	2326	1279	1415	1429
2762	hla2444	2224	2165	2250	3991	2409	2474	2532	1229	1337	1304
2902	HQ2660A	2275	2204	2229	2409	3925	2622	2870	1196	1424	1340
2988	HVO_1564	2344	2201	2273	2474	2622	3999	2887	1216	1374	1405
3051	Hbo3487	2361	2247	2326	2532	2870	2887	3908	1121	1357	1380
1461	HQ3028A	1251	1146	1279	1229	1196	1216	1121	4135	1571	1650
1798	rrnAC3457	1379	1407	1415	1337	1424	1374	1357	1571	5019	2930
1707	Hmu2492	1356	1344	1429	1304	1340	1405	1380	1650	2930	4401

734 symbols
consensus       ---------------------------------MADDLADRVRRALAVDAEE-FEARAAE
#oth            111111111111111111111112223333344442332351332.24163231531252
NP1074A         ::::::::::::::::::::::::::::::::MS:SE::AQIEA::S::R::::AS:VEA
rrnAC2772       MSATCCDGVATALSLSPPVWGMLNTHGCKPGDMS:SE:::::AEV::T:S:A::NE::R:
Hmu2859         ::::::::::::::::::::::::::::::::MS:SE::Q:::E::S::GD:::::::::
hla2444         :::::::::::::::::::::::::::::::MSTESV:::G::E:::::P::::D:::E:
HQ2660A         ::::::::::::::::::::::::::::::::::T:E::AE::D:::::::G::ND::LA
HVO_1564        :::::::::::::::::::::::LKAFDARTPG:S::::E::EDV:::::A:::::Q:KA
Hbo3487         ::::::::::::::::::::::::::::::::::T:K::::::DV:::::D::Y::Q:EA
HQ3028A         ::::::::::::::::::::::::::MLLDMEKQMT:TI:A:E:::TSEQK:T:D::V:R
rrnAC3457       :::::::::::::::::::::::::::::::::-M::IV:L:T:S::DETAAA:TE:VD:
Hmu2492         :::::::::::::::::::::::::::::::::-M::VV:L:::S:SGESDAE:RE:I::

consensus       EAEVLKREIRAGTFDNHQAIVGLEYEFYAVDDGRDA---D--E-----------------
#oth            21452163223.3..144321.2.3.3.11334233426246343222212211111112
NP1074A         :K:::RG::ED:::::P::::::::::::::AET:::::-::-:::::::::::::::::
rrnAC2772       ::QA::SAV:D:::::TE::::M:L:L::::EQT:::::-::-:::::::::::::::::
Hmu2859         :::W::A:V:D:::::TE::::::L:L:::::RT:::::-::-:::::::::::::::::
hla2444         :::IV:QGL:D:A:::::S:::F:::::::A:::WSEESRAG:YA:::::::::::::::
HQ2660A         D:D:V:D:LA::::::::::I:::::::::A:::W:ASN:GDVYG:::::::::::::::
HVO_1564        D:::::::L:E:::::::S:::::::::::S:::WSASE:DVHA::::::::::::::::
Hbo3487         D:::V:S:LA::::::::S:::::::::::A:::WSSSD:NM:NG:::::::::::::::
HQ3028A         ::ARI:HD::N:Q::SDHVA::::L:A:I::SKTQ-:::-::-:::::::::::::::::
rrnAC3457       Q:MQ:R:A:E::E:::EAFS::::I:L::INAEP:PPEP:DA:DSEEATEEDLDDDLSGS
Hmu2492         Q:DQ:RDA:E::A:::EDFA::::V:V::I:AEPEPA:A:DP:ASARSSEAALDDDLSGG

consensus       ------------------------------------------------------------
#oth            111111111111111111122111121111112211221111111111111111111111
NP1074A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC2772       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2859         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2444         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2660A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1564        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo3487         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3028A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC3457       SEAAWSGSLDAPAEPENGGGASLEPNGGGASLEPDEGDPLEPAGDESLDQDTGDAADESD
Hmu2492         S::::::::::::::::GGLGSLEPAG:::::DRDEDAPLEP:::::::::::::::::D

consensus       --------------------------------------------------------LMRV
#oth            12212111111111111111111111111111111111111111111111211112.322
NP1074A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC2772       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::Q::
Hmu2859         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::Q::
hla2444         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2660A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1564        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo3487         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3028A         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::APA
rrnAC3457       DAFGPGEGPSLDIDPDSPLADDEPETPENEAESAVESSVEEEDDEPYMDPEDWEGQ:T:L
Hmu2492         DTDGQGE:::::::::::::::::::::::::::::::::::::EPYMDPDDWEGR:AEL

consensus       PRRLLELIGFEKELGLHNAEMTTSPQPLNP------HGLRAQESEVRARLDAALQCASAE
#oth            .25211451231...1..1.44.4.232351111113.232.432252536413563682
NP1074A         ::::::Y:::::::::::::LS:T::::SE::::::Y::::::A::Q:K::::ETEVNR:
rrnAC2772       ::Q::::::::::::::::::Q:::::::T:::::::::A::RN:LK:S:MP:Q:RVRN:
Hmu2859         ::N::::::::::::::::::Q:::::::E:::::::::E::LA:L::N:AP::EQTHT:
hla2444         :::::::M:::::::::::::S::::::SD::::::::::::LA::::::E::ENT:GV:
HQ2660A         ::::::HV:::::::::::::::N:::::A::::::S::H::::::::Q:R:::::T:::
HVO_1564        :::::G:M::::::::::::::::::::::::::::::::::::::::::::::D::A::
Hbo3487         ::::::::::::::::::::::::::::::::::::::::::::::L:::T:::::T:S:
HQ3028A         :ETVF::N:CSP:::V::V:FH:T:DAIGAESDNGGS:F:R:A::LHHIR:SIRSHIDDV
rrnAC3457       :DVVF:GEA-N:::::::::VN:K:NSFDQ::::::T:MEV:TTA:EMQTKQ:R:Q::KH
Hmu2492         :ESIFGTAA-A::::V::::IN:D:DV:G:::::::T::AV:TTSIEM:IKK::DA:RQ:

consensus       GMRLVSDGLWTIPPAGETAREYLTDSVEDDGVRIATNMSDAVRYHAMAN--GDYAGG-ID
#oth            234..2.21.11..4112264..3243454.23415.11631..2112133334443457
NP1074A         ::A::::::::V::V::::AA:::::I:E::M:M:A:::R:::::::::::TE::PE:LQ
rrnAC2772       :I::::::M::V:::::::ET::C:C::QS::::G:::::S::::T:::::T::PSA:FE
Hmu2859         NIQ:::::M::V::N::::SG::C::::EQ:I:::::::A:::::::::::T::PS::MA
hla2444         :::::::A::::::T:::::G::::::DV:::TV:V:::::::::::::TG::EHR::TV
HQ2660A         :I:::::::::::::::::E::::N::D:::::::::::GS:::::::::::PRVPDTVM
HVO_1564        ::::::::M:S::::::S::::::::IT:G:::L:::::NS:::::::::::PT:PASFT
Hbo3487         ::::::::::::::T:::::::::::IS:G:I:V::::::S:::::::::::ET:T:QMS
HQ3028A         DRT::Y:S::::::E-TGTDA::RAGTTEH:IFF:E:VRPIP::I:LNEMIRERS::TVE
rrnAC3457       NCE::L:AM:::::E-:GSK:::SAHEMN:::VL:D::RQ:P::V:LD:EAL:H:::S::
Hmu2492         NRT::L:AM::::::-:GSVS::S:VE:R::IVF:R::RQDP::V:LD:EALAH:::E::

consensus       LDAPHVSLSADTVMPESLITSIQPHYQIPHAADLPEYFNYALRIAGPLLALGVNSPFFPP
#oth            332.23236221212.1.21.1...2.1122422241221.2.221.111131...11.1
NP1074A         :::::::::SE::::::::::::::::V:::H:::T::R::::V::::::VA::::::::
rrnAC2772       I:::::::Q:E::::::::::::::::::::P::::::S::::::A::::::::::::::
Hmu2859         ::::N:::Q::::::::::::::::::::::P::::::R:::::::::V:::::::::::
hla2444         VK::G:::A::::::::::::::::::VAQ:DT::QH:R:::::::::::::::::::::
HQ2660A         ::::::::P::::::::::S:::::F:VA::::::T::::::::::::::::::::::::
HVO_1564        ::::::::K:::::::A::::::::::V:::D::SYH::::::V:::::::::::::::A
Hbo3487         ::::::E:D::::::::::::::::::VA::::::T:::::::V::::::::::::L:::
HQ3028A         :GL:GLD-T:PSMLV:::A::::::L:::DPR:AAA:L:A:T:TM::::S:TA::::L:A
rrnAC3457       F:V:GY:G:FP:ILF:::A::::::L:::D::AF:::Y:A:I:TL::::::S:::::L:A
Hmu2492         FSV:GA:H:FP:ILF:::TS:V:::L:::DSDAF:A:Y:A:I:TL::MV::TA:::LL:A

consensus       DLYDDVADGEIV--LADAHMENRIAVFESVLNT-AD-------------EEKVRFPQDLD
#oth            12.24462555311224354.2.132..22114162111111111122255.131.7134
NP1074A         ::::--::::T::::D:CW::::VP:::::::P:::::::::::::::::R::S::K:I:
rrnAC2772       :::::AP:P:::::-:G:N:::::G:::::::P:P::::::::::GDSTPP::C::P:F:
Hmu2859         ::::::P:SR::::-DE::::H::G:::::::P:REDERTSRDGAGADAQA:::::K:FE
hla2444         ::::EGW:::R:::::EGAT::::H:::::::ART:::::::::::::::G:::::REFH
HQ2660A         ::::::GAQQ:L::-::G:A::::H::::::::::::::::::::::::A:::::::::N
HVO_1564        ::::ED:TADEI:::D:GWD::::::::::::S:G::::::::::::::H:::A::G:::
Hbo3487         :::::-::PTTI:::D::Y:::::::::::::G:E::::::::::::::A::::::D::S
HQ3028A         :C:AG:SAEVAADR::RTPH:L::PI::RAVD::GA::::::::::::::-:C:V:A:A:
rrnAC3457       EM:G:-T:::WL::CETT:H:L:::A::QSV:::SE:::::::::::::NP:::V:::::
Hmu2492         :M::A:E:PRAL:::E:T:H:L:::A::QSV:::SE:::::::::::::NP:::V:S:IE

consensus       TVEDAVDRVVADDTIV-------PMP---VPRG-DR--FDDDFATLRHKHGTYWRWVRPV
#oth            22331211114.52421111111.441124453141222315233122.1.11...2.1.
NP1074A         S:DE:L::IA::E:V:::::::::AD::::DPE:G::::::E::HF:::::SF:::::::
rrnAC2772       :::::I:DI:::::::::::::::VD:::L:S::T::::::::VH::::::S::::::::
Hmu2859         :::A:I:D::::T::::::::::::A:::AST::E::::::A::H::::::S::::::::
hla2444         DI:T::::I:::E:LI:::::::::::::E:E:T:::::::E:::F:T:::S::::::::
HQ2660A         :::::::::AD:A::::::::::::::::::::::::::::N:::::R::::::::I:::
HVO_1564        ::::::::::E:S:M::::::::::S::::E::::::::::::::::R::::::::::::
Hbo3487         D::E:::::AS:ES:::::::::::::::::::::::::::S:::::R::::F:::::::
HQ3028A         DIF:VI::I:T:P:L:ASSTLET:I::::ASDA::P::--C:LSVFPT:R::::::::::
rrnAC3457       DTT:V:G:::D::LFA::::::::FLREFLHDD:::TE:E:::WEFD::R::::::L:C:
Hmu2492         :TTEV:::::E::LFA::::::::FLREWIEE::S:SGLH:TYWEFD::R::::::L:C:

consensus       FDGA-----------------TRSSANARIEFRPLPGQPTVRDSIAFQAAFAGLMESLPR
#oth            23.4111111111111211113433212...1..122..124.322221322.1243124
NP1074A         :G:P:::::::::::::::::::T:::::::::::::::::::T:SLL:V::::::::::
rrnAC2772       :E::::::::::::::::::::::A::::::::::AA::::D:A:G:A:V::::::::::
Hmu2859         :::P::::::::::::::::::::A::::::::::S:::::S:AV::::V:::::K::S:
hla2444         :E:::::::::::::::::::S::::::::::::I::::::::::::::::::::QA::Q
HQ2660A         :::::::::::::::::::::S::::::::::::::A:::::::M::::T:::::K::::
HVO_1564        :::::::::::::::::::::S::::::::::::IA::::::::V:::::::::::R:::
Hbo3487         :::E::::::::::::::::::H:::::::::::IAA::::::::::::::::::::::K
HQ3028A         :C:QTPRGGAETTAVPTDHTGHTNH:SV:::Y::::T:::I::T:GV::LVT:VLHGAVT
rrnAC3457       VG:::::::::::::PVD::GASTEKSL:::Y::::T::HAK:M:GL::LTV::IRG:VV
Hmu2492         IG:D:::::::::::PVD::GAGDERSL:::Y::I:T::::A:T::V:VLT:::LRG:VV

consensus       REHPVIELDWETAEENFYAAARDGLDADLRWITADGTETTDTDAIYDDLFEHARDGLEAA
#oth            43..26614.42.241..4.224.262433.2442.642444222.312143.34..564
NP1074A         ::::IYHQ::A:::::::R:V::::A::I::R::::::::::EEL:AE:::I::::::LR
rrnAC2772       L:::IQS::::::KQ:::T:::N::R:KIE::::::AT::S:EE::GE::::::E:::QR
Hmu2859         L::::RS:E::::::::::::::::R::FE:::::::::SAV:E::GE:::L::E:::GR
hla2444         Q:::::G::::::RD:::::VAG::::EIE:VGL::ER::::::L:A::LD::EA::RT:
HQ2660A         :::::VNQS:S::R::::::M:S:::SRQ:::CN::V::I:QE:::::I:A::I:::T:S
HVO_1564        LD::::G:::::::::::T:M:E:PHG:::::DV::DDV:GAE-L:E::LV::::::RL:
Hbo3487         :R::::DQ::Q::K::::::M:N:F:SRQ:::AN::H:::NAAEV:::ILA::V:::KS:
HQ3028A         TN::LET:T:DD:::S::::VA::PT:T:A:VDDS::HQM:Q::::A:::SL::R::S:L
rrnAC3457       AD:::A::P:QE:RRS::N::D:::E:::S:V::Q:ER:A:H:::::EV::Y::L::AEQ
Hmu2492         AD::LA::P:QD::AS::S:::E:PG:::A:V::::QR:::H:::::EV::Y::R::ASQ

consensus       GCSEEEANRYLAPLRERVDRR-LTPARWKRDRVRDALDDGDDLAAAIWEMQREYIERQSE
#oth            132424256325.127.346315..14..543.643153261154.2742.34.246241
NP1074A         :LDA:AS:::IQ::::::::::V::::::YEH:A::VA::EPF:Q:V:G::A::::N:::
rrnAC2772       :L:A:::HG:IR:::::::::::::::::H:Y::RRVEENVP::E:::G::AT::RH:EG
Hmu2859         :L:T:Q:LG:IQ::K::::::::::::::HEQ:QT:V:E:VP::E:::G::SR:VD::::
hla2444         ::PD:::AAW:::::W::AN::T:::S:::::::ER:GA:::FET:VYDT:::::D::A:
HQ2660A         :::KST:ET:VE:::H::KTQ:M:::S::VTQ:::H:T::T:F:T:VA::::A::KE:R:
HVO_1564        ::::::::Y::E:::K::ETG:V:::D:::A::S::::G:G:FG::LR::::::V:::::
Hbo3487         ::::A:::::V::::V:AESG:R:::G::IN::H:::A::L:FD:::F:::::::D::::
HQ3028A         DV:D:TIEWA:T:IES:R:GPYQ::SE::::::EQ:VSA:TP:P:::TQ::TA:V:YAQ:
rrnAC3457       DI::ARIDE::G:IEA:Y:AG:M::SD::IA:::EY:::::::ST::QS:::D::AASR:
Hmu2492         DVP:SQIDEM:::IER:RTLG:T::S:::L:::GEY:SE-H::PD::C:A::D:Y:LSR:

consensus       TLLEGSFSDWL---
#oth            532224.52.4311
NP1074A         ::I::A:V:::Y::
rrnAC2772       N::::::V::FE::
Hmu2859         :::D:::T::::::
hla2444         ::I::G::A:ANSN
HQ2660A         :::DE::LA:E:::
HVO_1564        S::::A::::F:::
Hbo3487         ::::::::::::::
HQ3028A         GI---P:AE:S:::
rrnAC3457       YH---::EE:::::
Hmu2492         HD---T:A::::::