[F] (Apt) COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins 7 genomes BUD1368 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2117 - HVO_0334 Hbo1145 - Hut2490 hla0280 NP1254A HQ3228A

Pairwise sequence scores
Consensus score	1729	Hut2490	NP1254A	VNG2117	HQ3228A	hla0280	HVO_0334	Hbo1145
1198	Hut2490	1801	1052	1115	1061	1105	1082	1139
1326	NP1254A	1052	1730	1290	1213	1257	1272	1250
1390	VNG2117	1115	1290	1747	1238	1321	1320	1310
1469	HQ3228A	1061	1213	1238	1731	1426	1380	1436
1573	hla0280	1105	1257	1321	1426	1705	1490	1497
1549	HVO_0334	1082	1272	1320	1380	1490	1711	1533
1604	Hbo1145	1139	1250	1310	1436	1497	1533	1725

248 symbols
consensus       MNRAEKAALQLQAVAVLRMLKETRTYDELAELTGLPAGDLNRYVNGHVLPGTERAREVVE
#oth            .1.2..11...1..2...2..11...1..123..1111..1.........143..122.2
Hut2490         :K:V::TT:::R::S:::R::TD:::::::AE::FS:S:::::::::::::V:::::I::
NP1254A         :::S:::::::R::D:::T:::::::E:::DE::::::::::::::::::SET:::DI:D
VNG2117         :::::::T::::::D:::T::::::::::SAD::::::::::::::::::SAD::::::Q
HQ3228A         :::::::T::::::::::::::::::::::::::::S:::S:::::::::::N::SQL:D
hla0280         ::::::::::::::::::::::::::E::S:V::::::::::::::::::::D::S::::
HVO_0334        ::::::::::::::S::::::::::::::::::::::::::::::::::::V::::::::
Hbo1145         :::::::::::::::::::::::::::::::::::::::::::::::::::I:::::::Q

consensus       DVGRDALAAELEARVEFDDEGYVDNSGVVFDQSFLDLVAPVAAETFGFERPDVVLTAATD
#oth            42.312.12.141.132.11.....111.....1.3..21...2213213..21......
Hut2490         :L:HET::::I:S:I:R:E::::::T:::::::L::::GS::::::::::::A:::::::
NP1254A         SA::EL::T::N::IAV:E::::::TR::::::L:S::P:::::GL:IDP::T:::::::
VNG2117         NA:A:L:Q:::A:::HV::D:::::::I:::::::E::::::::::D:DA::::::::::
HQ3228A         :::QE::::::H:::::::::::::::::::::::N:::::::D::A:::::::::::::
hla0280         A:::::::D::L::::::::::::::::::::::::::::::::::E::S::::::::::
HVO_0334        G:::::::D::::::R:::::::::::::::::::::::::::NALDL:::::I::::::
Hbo1145         G:::::::T:::S::::::::::::::::::::::::::::::N:L::::::::::::::

consensus       GITLGAAMASYFDARCAYAKKSKETAVEEFIESRQRLASGIELTYYLPASAIDAGDSVLV
#oth            ...111.1.22112231...1.1..1111.1.2....21...21.1..22.223.14..2
Hut2490         :::IAG:::RH::VPVV:::::R::G:S::V:T::::TP:::I::S:::::L::::D::L
NP1254A         ::::A::::R::G:::::::Q:R:::::::::A:::::::::ID::::E:::::::::::
VNG2117         ::::A::L:G:YG:D:::::Q:::::::::V:A::::E::::F::::::::L:D::T:::
HQ3228A         :::::::::::::S:I::::::::::I:::::::::::::::::::::TC:VNT:E::::
hla0280         ::::::::::F::::L::::::::::::::::::::::::::::::::::::N:::T:::
HVO_0334        ::::::::::::G::L::::::::::::D::::::::::::::::::::::::D:ER:::
Hbo1145         :::::::::::::::V::::::::::::::::::::::::::::::::TR:LSS:EN::I

consensus       VDDLIRSGETQELLLDIALQADADVTGVFALIAVGDEGIDRAREITDAPVGALTTFDD--
#oth            ...11...1..11.1.112211.213...11.12.22.4321.35111..1.12323441
Hut2490         :::FV:::N::Q::A:L:DS:G:M:S:::TV::I:ET:L:AV:DAV::::A:F::LPEAT
NP1254A         ::::::::::::::::::GS:::::I:::::::::::::Q:::RH::::::::VERNG::
VNG2117         ::::::::::::::::::DA:G:::::::::::A:ET:V:::::R:::::::::DL::L:
HQ3228A         ::::::::::::V::::VG::::E:::::::::::TK::KK::TQ:NV:::::SE::TR:
hla0280         :::::::::::::::::::::::::::::T::::::K:MK::::::::::::::::E-::
HVO_0334        ::::::::::::::::::::::::IA::::::::::::TN::::L::::::::SS::-::
Hbo1145         ::::::::::::::::::::S:::::::::::S::T::::::::::::::::::::::E:

consensus       --------
#oth            11111111
Hut2490         APKTYARS
NP1254A         ::::::::
VNG2117         ::::::::
HQ3228A         ::::::::
hla0280         ::::::::
HVO_0334        ::::::::
Hbo1145         ::::::::