7 genomes BUD1387 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_0117 Hbo1379 Hmu2640 Hut1692 hla2493 NP1016A HQ3422A

Pairwise sequence scores
Consensus score	1632	NP1016A	Hut1692	hla2493	HQ3422A	Hbo1379	HVO_0117	Hmu2640
1186	NP1016A	1604	1093	961	1011	1068	1052	1127
1293	Hut1692	1093	1627	1044	1076	1110	1113	1169
1235	hla2493	961	1044	1611	1097	1096	1151	1055
1297	HQ3422A	1011	1076	1097	1638	1241	1213	1106
1354	Hbo1379	1068	1110	1096	1241	1621	1266	1174
1397	HVO_0117	1052	1113	1151	1213	1266	1605	1274
1359	Hmu2640	1127	1169	1055	1106	1174	1274	1632

226 symbols
consensus       VLRAAFAGSSYVGVFARATDDYLLVRPDADDDLADAMGAELDVPAVPTTVGGSGTVGALA
#oth            2..1212..2.1..1.211.241.1.1.21222322233..222415.111.11...1..
NP1016A         M::::LS:::::::::T:::E:::::::IEES:QSEFET::::T:::::IA::::::S::
Hut1692         L::T:::::A::::Y:::::E:I:::::::E:VI::F:S::S::I:E::I::A:::::::
hla2493         ::::T:T:::::::::::I::L::::::V:EE::::L:E::GAEPLL:::::AN:::S::
HQ3422A         M:::S::::P:::::::::::V::L:S:V:::T::::A::::I:::A::I::::::::::
Hbo1379         ::::S::::A::::::CV::HV:::::::E::VV:::T::::::::R:::::::::::::
HVO_0117        ::::S::::::I:::::::::A:::::::::S::EQ:AE:::::L:K:::::::::::::
Hmu2640         L:::::S::::::::::::::C::::::IEQS:Q::L:::::::V:::N:::::::::::

consensus       TGNENGLLVSSRVTEREKDRIEDAADLPVTELPGRINAAGNVVLANDYGAYVHPDLSREA
#oth            3..1..2..1211131.32213343232.3....2.......1.1.14..1..12.1211
NP1016A         V::::::::TE:::D::R::L:TETG:::V::::N:::::::::::NE::F:::::::D:
Hut1692         A::::::::T:::::Q:R::::ASI:A::V:::::::::::::::::N::F:::::::D:
hla2493         ::::::V:::A:A::::QS::AE:::CE:G::::E:::::::::::::::::::::P::S
HQ3422A         ::::::I::T:N::M:::EA::TT:SVS::::::::::::::I::::::::::::::T::
Hbo1379         M::D::I:::A:A:::::ET:::V:GV::::::::::::::::::::S:::::::::D::
HVO_0117        ::::::::::::A:S:::EALT::V::::Y:::::::::::::::::::::::AE::D::
Hmu2640         :::::::::::::RD::I:::I::V::::Y::::::::::::::C::T:::::AN::D::

consensus       VAAVEDALDVPVERGDLADVRTVGTAAVATNRGVLCHPKSTEPELDALEELLDVRADIGT
#oth            2431221.4..12..311112.1.1...1112.1.1...21131.22212211.21.2..
NP1016A         LS:I:E::S::::::RI:::Q:::::::V:DD:::S:::T:DEK::F::::FG:Y:::::
Hut1692         :Q::K:::::::::::IGGTQ:::A::::::::A:::::A:DT:::RVAD::::PT:V::
hla2493         IVTIRET:G:::V::::G:::::::::::N:T::::::::::S::Q:V::A::::::L::
HQ3422A         :ESI:S::N:::A::K:::::::::::::::::::::::AR::::E:I:DH:::::::::
Hbo1379         L:V::::::::A::::::::::A::::::::D::::::::R::::E::::::::::::::
HVO_0117        :::::E::E::::::::::::::::::::N::::::::::R::::E:::A::::::::::
Hmu2640         :SV::::::::::::T::::E::::::::::::::::::::D:::::::A::G:P:::::

consensus       INYGGPLVGSGLVANDNGYVVGEDTTGPELGRIEDALGYID-----
#oth            1...1..1...12.2531.11.21.1....1.1.21.112211111
NP1016A         :::::::::::::::NT::IA::E::::::::::::::F:Q:::::
Hut1692         :::::::::::::::G::::::Q:::::::::::R::::V::::::
hla2493         ::::A::I::::I:T:E:::::::::::::::::ET::F:::::::
HQ3422A         V:::A::::::I::GQT:::::::::::::T::::T:::LESITSE
Hbo1379         V:::A::::::::::EF::::::E::::::::V::T:::L::::::
HVO_0117        ::::::::::::::::ES:::::::::::::::::::D::::::::
Hmu2640         V:::::::::::L::T::::::D::S::::::::::::::::::::