7 genomes BUD1388 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_0235 Hbo1263 Hmu3148 Hut2230 hla0745 NP0196A HQ3647A

Pairwise sequence scores
Consensus score	910	HQ3647A	Hbo1263	HVO_0235	hla0745	Hmu3148	Hut2230	NP0196A
674	HQ3647A	1913	599	540	537	574	566	528
726	Hbo1263	599	1156	588	589	553	604	599
729	HVO_0235	540	588	1116	632	570	577	572
701	hla0745	537	589	632	908	616	575	574
687	Hmu3148	574	553	570	616	900	611	619
721	Hut2230	566	604	577	575	611	889	618
686	NP0196A	528	599	572	574	619	618	1055

246 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111113
HQ3647A         MYRWDFDYAECGALVVDGDCDSDSVSANNDTISHTQCNRDVEIGVDTDVNVDADKDPDAD
Hbo1263         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::V
HVO_0235        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::M
hla0745         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu3148         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut2230         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0196A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ---------------E-----------VTAVD----------------------------
#oth            233333444344433143434333434252212111111111111111111111111111
HQ3647A         RVAIEANSNERDQNI:SDEDVDDTTQYT::T:AESGDTAKSSTMTTNTESSEVSDNPDVR
Hbo1263         GDGSDDGGDEEASAA:ATATDGSASEF:VPTETE::::::::::::::::::::::::::
HVO_0235        RLYDAIAAVGPPRGI:CVFTATDELGS:DSA:::::::::::::::::::::::::::::
hla0745         :::::::::::::::-:::::::::::MEP::::::::::::::::::::::::::::::
Hmu3148         :::::::::::::::-:::::::::::MS::E::::::::::::::::::::::::::::
Hut2230         :::::::::::::::-::::::::::::::::::::::::::::::::::::::::::::
NP0196A         ::::::MCLAAVAAT:PVLPSDAEDGA:N::E::::::::::::::::::::::::::::

consensus       ---------------EWRAALAEAGELTPDIVDAIVDVHGDRGVRAIEAVSEERVKRYRD
#oth            1111111111222123.333121213.12321331335.12..32..1..2.4...2.1.
HQ3647A         THHVVSSSVSDETEAA::GE::ATEQ:::T:::T:IKY:::::A:::D::::::::::::
Hbo1263         ::::::::::NDRET:::R:::::::::::V:::VATI:DK:::::::::::G:::::::
HVO_0235        :::::::::::::::D:::::::T:R:S:Q::Q::::A::::::T:::::::R:::::::
hla0745         :::::::::::::::D:Q::I:::::::GP:AA:V::E:::::K::::::G:G:::::::
Hmu3148         :::::::::::::::::VSM:EA::A::::A::R::S::::::QQ:::::G:Q:::E:::
Hut2230         :::::::::::::::::::::S:::::S:::::R:TT:::S:::::::::A:D:::E:E:
NP0196A         :::::::::::::::T:ERT:EAD::::S:A:EQ:I:T:D::::::::::::::::Q:::

consensus       FTVVVGHDDEYVVEDGGCTCKDSSYNLDPEDPTERCWHVLAVAIARAIDAVDHHDMWYSD
#oth            .1....132..11.232.1.2.15....13.2332...21.241.222122.1...1.11
HQ3647A         :::::::N:::I::A::::::::L::::AT:::QC:::I::T:::ER:GV::::::::A:
Hbo1263         :::::::AA::::::::::::::::::::::DGQ:::::::A:V:ER:GE::::::::::
HVO_0235        :D::::Y::::::::R:::::::Q:::::-:EG:::::::::DV:E:L:EL:::::::::
hla0745         ::::::::::::I:::E:::A:AT::::A:::S:::::AI::DV:D:V:::::::::::E
Hmu3148         ::::::::::::::::::::A::E::::AT::D:L:::AI::R:::::::T:E:::::::
Hut2230         :::::::S::::I:GEA:::E:A::::::D:::DL:::::::L:::E:::::::::F::E
NP0196A         :::::::SE:::I::D::S:E::R:::::::::AL::::I:AK:::R::::::::::::E

consensus       VREFL-
#oth            .11.11
HQ3647A         :HD::S
Hbo1263         ::::I:
HVO_0235        ::::::
hla0745         ::::::
Hmu3148         ::D:::
Hut2230         ::D:::
NP0196A         ::::::