6 genomes BUD1420 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG2034 rrnAC3371 HVO_1703 HVO_1744 Hbo3134 Hmu2189 Hut2988 hla1823 - -

Pairwise sequence scores
Consensus score	6026	pNG2034	HVO_1744	Hut2988	rrnAC3371	Hmu2189	hla1823	HVO_1703	Hbo3134
3223	pNG2034	6196	2561	2860	2381	2889	2793	2861	2832
3742	HVO_1744	2561	6034	3241	2657	3203	3127	3339	3354
4696	Hut2988	2860	3241	6104	3413	4206	3751	3898	4135
3857	rrnAC3371	2381	2657	3413	5135	3707	3047	3165	3245
4564	Hmu2189	2889	3203	4206	3707	6137	3794	3788	3925
4588	hla1823	2793	3127	3751	3047	3794	6466	4255	4222
4809	HVO_1703	2861	3339	3898	3165	3788	4255	6043	4765
4910	Hbo3134	2832	3354	4135	3245	3925	4222	4765	6181

900 symbols
consensus       -------------------------------VDDLIEWLRNRPYYEGQIADHRRVPAREP
#oth            111111111111111111111111112222224253412341331321245313434232
pNG2034         ::::::::::::::::::::::::::MSQHNARETLS::KD:GH:S:::VHE:T:NGQ:A
HVO_1744        ::::::::::::::::::::::::::::::::NEFV::VQ::E::RD::QFQ:EI:::R:
Hut2988         ::::::::::::::::::::::::::::::::::VLP:::E::::::::::E::F:D::A
rrnAC3371       :::::::::::::::::::::::::::::::-----------------------------
Hmu2189         :::::::::::::::::::::::::::::::::ET:A:::E::F:::::V:Q:T::G:DA
hla1823         MIELRAHGGSSRTRTAPTATITPGGPHDTVA:E:A::::::::F::::::E:::L:::::
HVO_1703        ::::::::::::::::::::::::::::::::::::::::T::::::::RS:::FE::::
Hbo3134         ::::::::::::::::::::::::::::::::::::::::D:::::::MR::::::S:D:

consensus       AFADLDLEPRLADALADRGIDRLYRHQADAIEAVRDGDNVVLATPTASGKSLAYTVPAFE
#oth            554334454233321354122421311432231213132312215111111121221131
pNG2034         QTDS:SIL:SVKI::SQF::ED::E::ISS:::T:A:E:T:V::::::::::T:A:::L:
HVO_1744        ITRSCEM:R::::L::N::::G::A::T:::::::N:Q:::::::::::::::::I::I:
Hut2988         TDG:::VSD:::S::E:Q:V::F::::::::::::::E::::::::::::::::::::::
rrnAC3371       ------------------------------------------------------------
Hmu2189         TV::::VRD:::::::ED::EQ::A:::::VG::::::::::S:A:::::::::::::::
hla1823         :YR:V::A::M:::::KD:::::::::VE:::::::::DA::::E:::::::::::::::
HVO_1703        :::GV:::::::S::E::::::::::::E:V:::::::::::::R:::::::::::::::
Hbo3134         E:::VA::S::QS::S::::::::::::E::D:::::E::::::Q:::::::::::::::

consensus       RAMDHGGRTLYIGPQNALINDQAETLSDLADGLGFGSRVSVEQYTGRLSKGEKRDVRDRQ
#oth            214335232113212311221154212431552112342315421133145133532425
pNG2034         ::V::S:KA:::A:MR:::::::G::QAM::A::::EQ:D:GVK::QS::A:T:SIKQ::
HVO_1744        ::HKYD:::::::::V::::::ET::::F:APF---DDL::T::::S::SD:RQQA::ED
Hut2988         :::::V:T::::A::V::::::::::::::H::::::::T:DR::::::::::ET::E::
rrnAC3371       ------------------------------------------------------------
Hmu2189         ::LEDRRT:::VA::V::::::T::::T:::R:::A:G:::A:::::Q:QT::EQI:E::
hla1823         A::::::::::V:::::::A::E:S::E::H::::::G::::S::::::R:::::::::E
HVO_1703        :::::::::::L::::::VA::LD::::::R::::::::::G::::::::S:::E::K:M
Hbo3134         :::::::::::L:::::::A::D:::::::FT::::::::::::::::::T::::::::R

consensus       PTVLLSTPDMLHYGLLPHAH--RLWEWFFQSLETVVIDEVHGYRGVFGSHVALVLRRLNR
#oth            13221322111.222111.11111.311.22.12111..1.4...1...112134...3.
pNG2034         :D:::A:I:Q::LSF::Y::LTDH:R:L::Q::::I:::::T:::Y::::A::IF:::::
HVO_1744        :SIV:T::::::C:::S::G::D::RA::E:::L::V::::E:::::::::G::C:::A:
Hut2988         :::::T::::::::IM::::::::::::::R:::I::::::A:::::::::S::::::::
rrnAC3371       ---------:::::I::::::::::D::::R:::::V::::::::::::::S::M:::Q:
Hmu2189         :::::T::::::::I::::::::::K::::R:D:::V::::S::::::::::::F:::Q:
hla1823         ::::::N::::::A:::Y:G:::::D:::S:::Y:::::::S:::::::Q::MT::::A:
HVO_1703        ::::::N:::V::A:::::::::::::::S:::::::::::::::::::::::LI:::K:
Hbo3134         ::::::N::::::A:::::::::::::::S:::::::::I:::::::::::::T::::::

consensus       ICERFDA------------------DPQFVCCSATIGNPVEHAATVTGQPEDSFRLVDED
#oth            32112121111112222222222114.122......1..12.1.21114434123.113.
pNG2034         LLDHYGK:::::::::::::::::::::YI::::::::::D:::A:::R:T:::T:::N:
HVO_1744        ::D:LG:::::::::::::::::::::::::::::::::R:::::IA:::T:::E:::::
Hut2988         LA::::SG::::EPRSPERRTQSAGT::Y:::::::::::G::::::N:::P::::LTK:
rrnAC3371       :A:::::GGDSSESNGRRGDNATAGG:EW:::::::::::::::A::::::P::V:::::
Hmu2189         :A:::::::::::::::::::::::E:EWL::::::::::::::::::TAPS:Y::::D:
hla1823         T::::GS::::::::::::::::::S::::::::::N:::::V:::::RDPTGIT:::::
HVO_1703        V::::G::::::::::::::::::::::::::::::::::::::RI::ER::::T:::::
Hbo3134         ::::::S:::::::::::::::::::::Y:::::::::::::::R:::MEQA::::::::

consensus       TSATGPRHWLLWNPPEYDGD----------------GAG--------------SGRRRSS
#oth            2.22.323.12.1..11345211111111111111224.221111111111112.2.2.4
pNG2034         :::S:DKQ:VF::::QK:REDDSTADVDEETASTQQ:::QAGETTATQDDSDVG:E:L:Q
HVO_1744        ::E:::T:::F:Q:::::EGD::::::::::::::AP::::::::::::::::G:Q:::N
Hut2988         D::::::Q:VV:::::KR:-:::::::::::::::::G:::::::::::::::H:Q:::H
rrnAC3371       A::S:::::::::::::::::::::::::::::::::W:::::::::::::::::::K:N
Hmu2189         A::S::::::V::::::S:::::::::::::::::::W:::::::::::::::::::K::
hla1823         ::GR:::D:V::::::::D:W::::::::::::::QER:::::::::::::::::::K::
HVO_1703        ::G::ETN:::::::::ENPD::::::::::::::A:-:::::::::::::::::::::G
Hbo3134         ::G::AT::V:::::::RES:::::::::::::::::R:EE:::::::::::::::::::

consensus       HVETKRLFVDLVQRGLQTLAFTRARQTAERYATDSASDLRERGEHDLADGVGAYQAALTD
#oth            .2.2321.11.152.3..21.121..31.1.1331334.13..2422.4414..1.2.42
pNG2034         :::SV:I:A:::T::Y:::V::A:::GT:Q:VDWAD:K::S:::::I::S:H::H:::ES
HVO_1744        :G::M:::::::MQ:Y::V::::::::::::::I:SDT:A:::RA:I:QS:T::H:G:R:
Hut2988         :::A::::A:::::::::AV::GS::V::::::E:ERE:::::AGE::TKI::::::::S
rrnAC3371       :::::Q::::::E:::::VV:AGS::::::::S:::DE::K:::::::::::::::::::
Hmu2189         ::::R::::E::::::::VV::GS::::::::A:::EA::D::A:::::A::::::::::
hla1823         :T:S::::::::TA:A:::::::::::::Q::::::::::::::RG::GK::::::::N:
HVO_1703        :::::N::::::A::H::::::::::A:::::SE::::::S:::::::GE:A::::S::H
Hbo3134         :::::N:::::LS::H::::::::::A::::::E::E:::::::SEA:A::S::::::KH

consensus       DRRREIEAGLHSGDIRGVWSTSALELGVDVGGLDAVLLDGYPGTRMSAFQRAGRAGRGDD
#oth            11.131.43.21.232.1.1.2.....1.1.1..1.21......2.412.1.......31
pNG2034         E::::L::::K::::::L:::R:::::I:I:S::::I:::::::G::T::::::::::::
HVO_1744        :::AT::TA:::::CA:::::::::::::I:S::::::::::::Q:AT::::::::::T:
Hut2988         :::::L:::::D:S:::::T::::::::::::::::V:::::::::ET::::::::::E:
rrnAC3371       :::::L:Q::Q:::L:::::::::::::::::::::::::::::::R:::Q:::::::T:
Hmu2189         ::::RL:RE:K::AL::::::N::::::::::::::V:::::::::QT::Q:::::::R:
hla1823         ::::::::D:::::L:::::::::::::::::::::I:::::::::::Y:::::::::::
HVO_1703        :::::::::::D:::A:::::N::::::::::::V::I::::::::::W:Q::::::::R
Hbo3134         EK::K::S:::D:SVT:::::N:::::::::::::::I::::::::::::Q:::::::::

consensus       PALVALVGGEDQLDQYLLRHPEELFEGEPEQAVTNPENEQLLPDHVACAAAENWLSPDDD
#oth            22..21.21111....1442.44111541.2.341.3.432115.342..4142.213.1
pNG2034         SC::IM::SDNP::::::KE::Q::::GA:::AV::S:RSA::E:LV:::DDHY:::::E
HVO_1744        :S:::::AS:::::::VIK::N::::QT::R::A::S:SH::KL:THA::M:GP:RTA:E
Hut2988         :::::::T::::::::VA::::A::DR:::::L:::A:D:I:::::RS::R::::::G::
rrnAC3371       ::::::::::::::::V::N:DA:::TGA::::::::::::::G::HA::C:::::::::
Hmu2189         ::::V:::::::::::VVDN:DT:::HP:::::::::::::M:A:ACS::R:T::K::::
hla1823         ::::VM:::::::::::M:N:SDF::AP::D:ICD:::G::::G::::::D:S::::A:E
HVO_1703        ::::V::::::::::::MN::A:F:D:D::R::SD:::DH:::S::::::::::::TE:E
Hbo3134         D:::I:::::::::::::H::::FWD::::R:IC::T::E:::::::S:::::::K::::

consensus       RHFGETFPDVVSDLEADGRLDRRETDDGIRW--THAGSGSPQHEMSLRTIDDREIKL-VD
#oth            33..222.33.24.153.5.41.2223141.1134414422332331.22323213.144
pNG2034         QY:::AL:EM:DQ:T:E:::-K:TNEEQV::::-E:ANNDI:IQTDI:N::EE:::::::
HVO_1744        AY::S::::I::T:TN::E:T::Q::Q:LE:RR:AS:RTVNPY:QG::::TE:MVT:R:R
Hut2988         :::::::::::A:::SR:D:E::T::A:T::::LYD:G:::A::T:::SA::::::::RE
rrnAC3371       ::::::::::::G::SA:K::::Q::Q:M::::--L:N:::H:::N:::V::G:V::::A
Hmu2189         :Y::::::AL:A:::R::::A::T:AE:T::::VYG:E::::::T::::V::QS:Q::RH
hla1823         :F::::::G::A::TDE:I:::::VA::::::::::::S:::QAV::::AG::::D::I:
HVO_1703        SK::AP::GI::::::::T:A:::::::L::::::D::E::::A::::::T:::VQ::M:
Hbo3134         ::::::T:::::A::TA::::::::::::::::::S::::::::::::S:ES::VD::L:

consensus       GGRNDVIASLPFGDALRDAHPGAIYHHQGQTYEVTDLDLDRDVAELDRTWADYYTRVLHE
#oth            344413212.4331.1..1..1.1.121124.1.33...2322.5.33232132.12231
pNG2034         RN:GEILG::ERDA:::::::N:::MYDK:S:K:VE:::EERT:Y:ESVETSE:::A:R:
HVO_1744        ::AT:ELGK::LNA::::V:::::::::::N:::QS::::::::W:AE:DS:HQ:::QY:
Hut2988         R:S::::::::::::::::::::::::::TK:::V:::::H:::T::::Y::Q:::::::
rrnAC3371       K:--::::K:SVE::::::::::::::::RR::::::::NAG:::::::::::F:::::D
Hmu2189         :E--:T::T::L:::::::::::::::::T::::::::::HGI::::::::::F:::R::
hla1823         SS::ETV:::G:::::::::::::::Q::R:::::N::::::::::QSS::::::QP:T:
HVO_1703        SRNDEI::T:A:D::I:::::::V::::::::::AE::::::::R:QP:::::::::::D
Hbo3134         :RS:E:::::S:::::::::::::::::::S::::E::::::T:I:QP:::::::::::D

consensus       KTITVEADLREKPLS-AREDVPVRFADVTMRKQITGFERRDGRRGEAIGRESLD--LPET
#oth            1421113124323141313123121121.222.1..13.315531143224413111.11
pNG2034         :EV::NDT:DTRT:EFDG::MKATLGSL:V:N::::YL:YSSP:D:SPSEHEFETP::PS
HVO_1744        ESM:I:E:SAT:::A:T:D::T:H:::::R:::V:::Q:::H:T::IMTE:A:K::::::
Hut2988         :::::::::::::FP:G::S::::::::::H::::::::H:A:S::::S:::::::V:::
rrnAC3371       :::::::::A:RR:P:T:::::::::S:::::::::Y:::::SS::VL:QR:::::::::
Hmu2189         :E::::::::ADT:D:::P:::::::::::::::::Y:::::QN::V:::R:::::::::
hla1823         :D:V:N:::G:RE:::::P::::::::::VTE:::::V:K:TAT::SL:ESV::::::::
HVO_1703        :H::::R:ILS:::::::S::E::::E::::::::::::::PK::TT::QQL::::::::
Hbo3134         ::::::E:::S:::::::P:TE:::::::::::::::::::PK::::::::::N::::::

consensus       TLRTKALYFTVPGDLEREMRALG-----------------------------GDDGDFPG
#oth            213.21.1332.532.25225532222222222233332234322425442324344141
pNG2034         EIA:TG:F:EA:QKI::K:LKQV:::::::::::::::::::::::::::::DSPEQYLS
HVO_1744        ::S:R:::V:L:PG::SL:QTMS:::::::::::::::::::::::::::::---:S:E:
Hut2988         S:::R:::YAL:PE::ADL::A::::::::::::::::::::::::::::::----::::
rrnAC3371       ::E:::::H:::S:::::I:QGAYGAESGSESGDGVQSGDAVTDGGDA::::::::::::
Hmu2189         ::::::::::::A::::A:LGEA:::::::::::VPATDDGTADGRDRPPAPD:P:::::
hla1823         :::::::::P::::I:S::::::ARDADADGTNEAADADDTEAVTDGGEGLS:GEHA:N:
HVO_1703        S:::::::::::::V:S:::E:S::::::::::::::::::::::::SDRAE:R:YG:N:
Hbo3134         ::::::::V:::R:V:AQ:::M::::::::::::::::DETREDGAGQYELS:G:YG:A:

consensus       GIHAAEHALISLFPLELLCDRGDIGGLSTPHHPHTDQSTIFVYDGHPGGVGLTRAGYDDI
#oth            11..21.131123.244....2.1.12..25.21.35212.21.111..2.231312262
pNG2034         :L::I:::::::Y:S:V::::::::::::VS::Q:VGG:V::H::Y:::A:YC::AFEQL
HVO_1744        :L::VQ:::VAT:::VI::::R:V:SV::AE::Q:ET:AL:M::SYR:::::A:N:::H:
Hut2988         ::::::::M:ATM::SF::::R::::::::::::::R::::I:::Y:::::IAE:::ES:
rrnAC3371       A:::::::M::M::F:Y:::::::::::::R::::GEP:::I:::Y:::I:::::::H::
Hmu2189         ::::::::A::ML:F:Y::::R:V::::::L:::::EP:::::::::::::IV:SA:::V
hla1823         :::::::GI:::::FH:::::A::::I:::Y:::::APAV::::::::::::::R:HER:
HVO_1703        :::::::G:::::::R::::::::::::::Y:A::::::::I:::::::::I::::::IV
Hbo3134         :::::::GM::::::SF:::::::::::::::T::::::::::::::::::::EN:::EV

consensus       EGLLATTAELLADCDCEDGCPACVQSPHCGNANDPLDKALAVRLLEALTD----------
#oth            25.343.431243.2.21...1.11..1..11.21.2.44.451143.546543232211
pNG2034         DS::SQ::D:::S:S:S::::S:IH::::::G:RS:S:DH:N:V:RD:I:::::::::::
HVO_1744        :::FQH:W::::::G:S::::::I::::::R::E::::R::AT:TM::A:PSRQAADSTP
Hut2988         GD:A:::G::V:::::::::::::::::::::::::::G::IE:::::VEGDNASE::::
rrnAC3371       GP:MD::LSM:TA:::A:::::::::::::::::::::HG:IH::DG:LNR:::::::::
Hmu2189         :::::::LSM:RS:::A:::::::::::::::::::::G::TY::DG::E::::::::::
hla1823         :E:M:R::R:IDT::::G:::::::::::::::E::A::P:::::::::TDE::::::::
HVO_1703        :::MRQ::::IS:::::::::S:::::Q::::::::A::E::L:::S::GTRA:::::::
Hbo3134         :T::RR:H::IR:::::::::::::::Q::::::::S::E::H::A::SGEGESSRKLTP