6 genomes BUD1431 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG7194 HVO_1407 HVO_A0226 Hbo0138 Hmu1834 Hut1161 hla2059 - -

Pairwise sequence scores
Consensus score	692	HVO_1407	Hbo0138	Hut1161	pNG7194	Hmu1834	hla2059	HVO_A0226
425	HVO_1407	1668	683	326	282	301	330	333
385	Hbo0138	683	1671	326	273	298	304	303
512	Hut1161	326	326	691	405	394	418	458
468	pNG7194	282	273	405	692	491	422	407
499	Hmu1834	301	298	394	491	690	426	423
502	hla2059	330	304	418	422	426	687	455
522	HVO_A0226	333	303	458	407	423	455	735

234 symbols
consensus       -----MTDD--WDDVGYVISSRYRVAVLRRLSE-GPATPSRIADDSDCAQAHVSRALQEL
#oth            11111132522.1421112..2..142231.2121132.14..52536233.1....21.
HVO_1407        :::::::ET::::SA::IA:::::L::C:Y:::H:SGL:::::AE::L::P::::::S::
Hbo0138         ::::::N:L::::TA::IA::::::S:CKY:DRE::EL:::::SKLGF::P::::::S::
Hut1161         :::::::S:::::EI:::V::K:::K::Q:::::S::P::T::E:TG::VS:I:::::D:
pNG7194         ::::::A:FDQ::E:S:::::::::ET:::::::::::::L::::REMSI::::::::::
Hmu1834         ::::::::PD:::::SF:::::::::AM:::D::::S:::N::::ASVGL::::::::::
hla2059         ::::::S:E:::NAI:F::::N:::T:::::N::::::::Q::G:E:I:IT::::::R::
HVO_A0226       VSSVGG:::VP:::::F::::::::S::D::::::::::TQ::T::ES:V::::::::::

consensus       RERNLVELLVPESRKKGRVYGITDEGERIWERIRAQNMA---------------------
#oth            11142.1...11412...2.12.3414422343363332222221222211222122212
HVO_1407        :::GI::::::::QQ:::L::L::L::LAY::VALDQE::EITVVDDGEFPAPELTSELR
Hbo0138         :D::V::::::::QQ:::L::L:R::KQALT:L:GDAASVSVSFVEERSFPHDSLIDHLC
Hut1161         :D::::::::::::::::I::M::R:QDV::I::E:DLV:::::::::::::::::::::
pNG7194         ::SE::D:::S:D:::::::D::KK:VD:::T:ERK::::::::::::::::::::::::
Hmu1834         ::SE::D:::SDE::::::::L:E::D:V:QT:E:E::V:::::::::::::::::::::
hla2059         G::D::::::::N:R::::::::EK::::::EMQS::L:E::::::::::::::::::::
HVO_A0226       :D:S::::::::Q:R:::::::::DA:N::HV:QT:Q:::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            222122112122222222222222222221111222221212112212211221212121
HVO_1407        EAYGDALRAVAWCEPVQTRIRFFEQSLLDRYDEDTVKTLVATL:TNEEAIDQPLEDLPIG
Hbo0138         DEHGEELRLVVARNGDDSDVFVASEDVQKRYDEQSIARLIAALRAGETTIDDKLMDVPTG
Hut1161         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7194         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1834         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2059         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_A0226       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------
#oth            222222222222121122221222211212222112222221211222221111
HVO_1407        GPELVAFAIDNTLIVRVPLEDGVKLLVSLDASIDVTLNELRDSCRQMSAVALDS
Hbo0138         ENQFAVRGLEHSLLVRFSVDDDAEILVALEPDADVNVPAFIDACRRRLKD::::
Hut1161         ::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7194         ::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1834         ::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2059         ::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_A0226       ::::::::::::::::::::::::::::::::::::::::::::::::::::::