6 genomes BUD1435 6 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0329 HVO_1510 Hbo0043 Hmu1210 Hut1327 hla2445 - -

Pairwise sequence scores
Consensus score	2568	hla2445	Hut1327	rrnAC0329	Hmu1210	HVO_1510	Hbo0043
2081	hla2445	2559	1938	1932	1889	1961	1930
2248	Hut1327	1938	2580	2083	2125	2017	2000
2265	rrnAC0329	1932	2083	2551	2214	2072	1998
2254	Hmu1210	1889	2125	2214	2554	1985	1968
2252	HVO_1510	1961	2017	2072	1985	3261	2595
2215	Hbo0043	1930	2000	1998	1968	2595	3141

444 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111121221111122211122111121121111111111112112111
hla2445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1327         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0329       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1510        VVVTQHPLNVRDTVGGKRLNRSSGTSLTRCLTTTRR:IRRVPRRVEFFQGTLAQ::QSEI
Hbo0043         ::::::::::::::::MRVW:::::VVVRCLNDTRRTLRRIPRRVEFFQGTLAHITESEI

consensus       --------------------------------LD-MGTHVIEAGFPVNSDAEFEAVRDIA
#oth            22111111111111111111111111111122112.1............1......2..1
hla2445         ::::::::::::::::::::::::::::::::--::N:::::::::::::::::::S:::
Hut1327         :::::::::::::::::::::::::::::::V::E:::::::::::::::::::::::::
rrnAC0329       ::::::::::::::::::::::::::::::::--::::::::::::::::::::::::::
Hmu1210         ::::::::::::::::::::::::::::::::--:::::::::::::::::::::::::T
HVO_1510        EDVRIFDTTLRDGEQSPRTSFSYEEKRDIAET::D::::::::::::::E::::::A:::
Hbo0043         DGVRIFDTTLRDGEQSPRTSFSYEEKRDIAAT::E:::::::::::::::::::::S:::

consensus       AATDTTTCGLARVVEKDIEAALDSGVDMVHTFVSTSDVQLQDSMHATRQEAVERAVESVE
#oth            11142.1.......12.11..1.1..111.1......1..2.....1111.222.132..
hla2445         :::N::V::::::::G::D::I::::E:::V:::::::::E::::::::::KQ:::AA::
Hut1327         ES:T:::::::::::::V:::I::::ELI:V::::::I::::::::::ED::::::::::
rrnAC0329       ES:QV::::::::::::::::::::::::::::::::::::::::::::::LDT::DC::
Hmu1210         E:SSV:V::::::::::::::::A:::L:::::::::::::::::::::::LDS:I::::
HVO_1510        :S::A:::::::::D:::::::::::::::::::::::::A:::::S:E:::::::R:::
Hbo0043         ::::::V:::::::DT:V:::::A::E:::V:::::::::A:::::SKE:::::::::::

consensus       RVKDAGVECMFSPMDATRTDEDFLIEVVEAVSEAGTDWINIPDTCGVATPTRFADLIEAV
#oth            3111....1...........211.311211122..2..1.1...1...1.21.342145.
hla2445         Q:::::::::::::::::::P:Y:R:I:::::D:::::::::::::::M::S:GKTVK::
Hut1327         :::::::::::::::::::::::::D:::::T::::::::::::T:::::G::QEMVGK:
rrnAC0329       MI::::::::::::::::::::::V::I::T:A::A::::::::::::::R::Y::::I:
Hmu1210         :::E::::::::::::::::::::VD:I:G::::::::::::::::::::R::Y::::M:
HVO_1510        H:R:::::V::::::::::::::::::::::::::V::::L:::::::::::::RMVAT:
Hbo0043         ::::::::V:::::::::::MT::A:ILS::DD::V::V:::::::::::::::N::RE:

consensus       RAHTDARIDVHTHDDFGLASANAISGFEAGAAQAQVSVNGIGERAGNAAYEEVVMALESL
#oth            243...21...1.....1.2...32.1.1.12.......................121.1
hla2445         VNA::::V:::::::::M:A:::VM:::N::E::::::::::::::::::::::::V::V
Hut1327         V::::::V:::::::::::T:::L::::::G:::::::::::::::::::::::::::::
rrnAC0329       DDC:::Y::::::::::::::::::::::::S::::::::::::::::::::::::::::
Hmu1210         D:E:::::::::::::::::::::::Y:::::::::::::::::::::::::::::::::
HVO_1510        :E:::::::::A:::::::::::MA:::::::::::::::::::::::::::::::A:::
Hbo0043         :Q::::H::::A:::::::T:::MA::::::::::::::::::::::::::::::SAK::

consensus       YDVDTGIDTTRITELSRIVEEASDIPVPANKPVVGRNAFSHESGIHAAGVIENSDTFEPG
#oth            .1.1.....12..1.1121.11.1121.1....1.2...1.............1....1.
hla2445         :G::::::::Q::K:A:::::::::::::::::T:::::A:::::::::::::A::::T:
Hut1327         :::::::::::::::::LI::K:GVDT:G::::::D::::::::::::::::::::::::
rrnAC0329       :::::::::::::::::::::K:::G::::::::::::::::::::::::::::::::::
Hmu1210         :::E::::::::::::A:I::K:G:D:::::::::A::::::::::::::::::::::::
HVO_1510        :G::::::::K::::A:V::A::::::::::::::::::::::::::::::::A::::::
Hbo0043         :::::::::E::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       VMTPEMVGAERELVLGKHTGQHSVRERLVDAGFDPTDAEVREVTRRVKDYGAEKERVTMA
#oth            .........3.11.......3....11.211.12.2131..31.1...12.112311133
hla2445         ::::::::::::F:::::::T::::KH::E:::::::S:::RI:K:::E::SG:RQ::AG
Hut1327         :::::::::::::::::::::::::::::E:::E::EQ:::T::::::E::::QN:I::D
rrnAC0329       :::::::::T::::::::::A:::::::::::Y::SE:::::::::::E::::-:Q:::S
Hmu1210         :::::::::K:Q::::::::::::::::::::Y::::EH:::::::::::::::K:::::
HVO_1510        :::::::::T::F:::::::T::::K::A:I::::S:::::::::::::H:::::::DDS
Hbo0043         :::::::::Q::F:::::::S::::K::E::::R:D:S:::A:::::::T::::::::T:

consensus       VLERFAEDVGVDRED----EEVRA
#oth            31211.1121132242111....2
hla2445         DV:::::EADI:::E::::::::I
Hut1327         ::::::R::D:::AR:::::::::
rrnAC0329       :::::::EI::TE:S:::::::::
Hmu1210         E:R:::::I::PESQ::::::::V
HVO_1510        T::V::R:::ITH::DTE::::::
Hbo0043         ::T:I::::::GH::ETEH:::::