6 genomes BUD1481 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2497 rrnAC2021 rrnAC2718 rrnAC2923 - Hbo1553 Hmu2751 - hla2707 NP0572A NP3822A -

Pairwise sequence scores
Consensus score	1183	Hbo1553	rrnAC2718	NP3822A	hla2707	rrnAC2021	VNG2497	NP0572A	rrnAC2923	Hmu2751
610	Hbo1553	1248	622	510	503	414	422	421	399	477
640	rrnAC2718	622	1238	528	485	429	429	437	471	546
793	NP3822A	510	528	1304	792	750	487	471	537	506
759	hla2707	503	485	792	1270	787	482	454	489	505
710	rrnAC2021	414	429	750	787	1252	478	466	453	493
742	VNG2497	422	429	487	482	478	1259	657	631	646
736	NP0572A	421	437	471	454	466	657	1181	708	686
784	rrnAC2923	399	471	537	489	453	631	708	1227	761
789	Hmu2751	477	546	506	505	493	646	686	761	1242

183 symbols
consensus       ---------MEKVSIDDVD---SPMGPASVRRPLSDALGTEHVALNYYELAPGESFSGGL
#oth            111111222.23342.222334432133343321344.22334.3.312.3..1212212
Hbo1553         :::::::::::HIDV::I:TFPH:::ST:GGQA:::E:DATN::::R:T:E:::GS::::
rrnAC2718       :::::::::::H::V:EIE::PQA::GDVD::G:A:P:::TD::I:R:V:D:::A:::::
NP3822A         ::::::::::R::A::E::IEN::L:VH:::::V::::::::F:M::F::Q:::::::::
hla2707         ::::::::::R:AA:::::VVTN:::VHD::K:V:RV:D:::::M::F:::::DA:::::
rrnAC2021       ::::::::::NT:T::::PVERN::QVHDI:K:V:RT:::::F:A::F::E::D::::S:
VNG2497         MRVTPPLPR:RT:RL::L:::::R::::ARSL::T::::LSDA:M:V::::::D:::Y:F
NP0572A         :::::::::::T:D:::I:::::W::::::K::VGK:::A:EL:::::::::::::AF:Y
rrnAC2923       ::::::MAT:::::L:A:E::::R::::::K:A:AGP:::DNI:::H:::::::::GF:Y
Hmu2751         :::::::::::RT:::::::::ARI:::A:K:A:GP::E:TE:::::::::::D::GF:Y

consensus       HAHHDQEEVFYVLSGTATFETEDG-------DVAVGAGEAIRFAPGEFQRGR--NEGDER
#oth            .2.62.....1144.22..2264212221316.51241.221.31.1215.522243.12
Hbo1553         :T:L::::::::::::V::Q:VE::::::::S:E:SED::V:::::DYHH:T:::QS:DP
rrnAC2718       :::L::::::::VE::::::HRTDPAGE:SEM:T::PD:VV::::::Y:Q::::::S:D:
NP3822A         :T::::::::::Q::E::::VT:EPDSSTTEA:TA::::V:::P:::::E:YNDA:N:DP
hla2707         :T:G::::::::::::::::VGRE:::::RER:D:::::L:::::::::S:FVREDA::D
rrnAC2021       :R:::::::::IEQ:QT:::VGLD:::::REE:D:SG::L:::E:::::E:Y:::S::::
VNG2497         :::AA::::::::A::V::R:L:::::::::::::S:::LA::G:::::::V::::::::
NP0572A         :::EK::::::::D::V::::D:::::::::E:V:ED::::Y:EA::::::V::::S:::
rrnAC2923       :R:P::::::L:Q::::::::::::::::::::R:::::::::::::W:::H::::::::
Hmu2751         :R:S::::::::FQ:::::::::::::::::P::::PD:V:::::::W:L:::::A::::

consensus       VVALALGAPGASHD---IESLRHCPDCGEETTQAIELTDDGDFLLT-CPECGTETGRF--
#oth            1322.3...55631122334443.32.33325354541141435423.62.135434251
Hbo1553         ATV::I::::PQ::WEQ:RVPIP::::EDVDALG:RF::::ETA:S::::::RDVEI-::
rrnAC2718       :::::::::MN:TE:::GRVAQP::::-DSDVL:L:PA:E:-:::V:::D::::VEPDL:
NP3822A         ::GF:::::SSK::WEA:::VM::G::::::GHSMS:::E:S:SF:::G:::N:IAM-::
hla2707         :::W:F:::::R::WDQ::::IE:RE::::R:H:T:M::E:R:RF:::S::::SFSP-::
rrnAC2021       :IGW:F:::::T::WDA:::RA:::E:DT::::SVA:A:-:R:E::::T:::NVQ:--::
VNG2497         :R:::V:::QDAG::::T:T::E:::::G::::E:T:A:AR:EIH:V:ES:::I::::D:
NP0572A         :R:::V:::AETEE:::LTL::A:ES:DGR:E:E::P:A:R:A:I:R:VD::::::::S:
rrnAC2923       :::::::::QEMG::::TDM::::EE::GR:HNYV:M:ANR:A:V:R:A::DA:::::T:
Hmu2751         :::::V:::E::G::::T:MV:A::::E:R:E:TVDWA::::A:V:L:VD::AR::::EY

consensus       ---
#oth            111
Hbo1553         :::
rrnAC2718       :::
NP3822A         :::
hla2707         :::
rrnAC2021       :::
VNG2497         :::
NP0572A         :::
rrnAC2923       :::
Hmu2751         SSH