6 genomes BUD1495 6 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC3226 HVO_A0154 Hbo3749 Hmu2649 - hla1940 NP5136A -

Pairwise sequence scores
Consensus score	4142	rrnAC3226	HVO_A0154	Hbo3749	NP5136A	Hmu2649	hla1940
3231	rrnAC3226	3982	3078	3120	2692	2924	2845
3604	HVO_A0154	3078	4088	3931	2878	3083	3009
3620	Hbo3749	3120	3931	4073	2880	3108	3030
3259	NP5136A	2692	2878	2880	4315	3219	3067
3518	Hmu2649	2924	3083	3108	3219	4179	3386
3448	hla1940	2845	3009	3030	3067	3386	4369

605 symbols
consensus       -----MTAS-ALL----QSDLLPEALNISFKLIPAIMVIGMLALFLAIGYVFKVADTEGM
#oth            1111123324322111133411112131211131313133.131..21.11.1..1.12.
rrnAC3226       :::::----:---::::-----------------------:M:S::V:::::::::::::
HVO_A0154       :::::::::VF:Q::::SG:::::::::::::V:::::V:::::::::::::::::::::
Hbo3749         :::::::T:IL:Q::::S::::::::::::::::::::V:::T:::V:::::::::::::
NP5136A         MNIAALA:TL:M:PLQVEEA::::G:D:G:::L:::I::V:MLS:::V:FF::::N:DD:
Hmu2649         ::::::SG-:L::::::::G::::G:E:::::::G:::TA::L::::V::::::::::::
hla1940         :::::::G:S:::::::::E::::::D:::::V:S:L:::::G:::T:::::R::::DN:

consensus       WVAGRSIGNIENGMAIGANWMSAASYLGLAALIALAGFYGLAFIVGWTTGYFILLIFLAA
#oth            .....1...1..................1.121..3.1...1.11..11...1....1..
rrnAC3226       :::::G::::::::::::::::::::::::G:V::S::::::::::::::::V:::::::
HVO_A0154       ::::::::::::::::::::::::::::::G:V::S::::::::I:::A:::V:::::::
Hbo3749         ::::::::::::::::::::::::::::::G:V:::::::::::I:::::::V:::::::
NP5136A         :::::::::V::::::::::::::::::M::::::D:V:::::V:::::::::::::M::
Hmu2649         :::::::::V::::::::::::::::::M::T:::F:::::::V:::S:::::::::M::
hla1940         :::::::::V::::::::::::::::::M::S:::::::::V:V::::::::::::::::

consensus       QMRRFGKYTAPDFVGDRFNSDTARAIAALTTFLIGFVYAVGQARGMGLVGLYIFG-----
#oth            .1..................11...21.3..2..11..12...1..1...2.11.22222
rrnAC3226       ::::::::::::::::::::P::::L::F::L::AY::S:::::::::::Q:V:::::::
HVO_A0154       ::::::::::::::::::::::::::G::::I::::::S:::::::::::::V:::::::
Hbo3749         ::::::::::::::::::::::::::G::::I::::::S:::::::::::::V:::::::
NP5136A         ::::::::::::::::::::::::::::I::::::::::L::::::::::M::L:DINNV
Hmu2649         :::::::::::::::::::::S:::M::V::::::::::I:::::::::::::::DIG::
hla1940         :L::::::::::::::::::::::::::V::::::::::I:::K::A::::::::NYGAY

consensus       ---PGLDDYQTMVVVMMAITVGYLTLSGMLGATKNMAVQYVILIVAFLAGLYAVGFTQGY
#oth            11211132124.2121.31.11..21...1.....111.11...2..1311211.223.1
rrnAC3226       :::---L:IIP:I::::T::::::A:::::::::::::::T:::::::::V:V:::S:::
HVO_A0154       :::---T::V:::I:::::::::::I:::M::::::::::::::I:::TAV:V::::G::
Hbo3749         :::---T::I:::::::::::::::I:::M::::::::::::::::::TAV:V::::G::
NP5136A         VPI::::A::A:M:LF:IV:IA::S::::::::::::L::::::::::V::L:T:WAA:F
Hmu2649         ::I:::SG::S:::L:::::::::::::::::::::T::F:::::::::::::::Y::::
hla1940         ::V::::G::V:::A::VV::::::::::::::::QT:::T:::F::VL::F:::Y:N::

consensus       STVLPQIEYGQLIGDLSAEFSEPFANASFYLWIATAFSLIFGTCGLPHVLVRFYTVENER
#oth            .....11...2..23.13...1..22421.1.1..2.1.11...............11.1
rrnAC3226       ::::::::::A::A::GR:::A::V:QP::::V:::::::V:::::::::::::::RS::
HVO_A0154       :::::H::::::::E::T:::::::::G:::::::::::::::::::::::::::::::K
Hbo3749         ::::::::::::::Q::::::::::::G:::::::::::::::::::::::::::::::K
NP5136A         ::::::L::::::::::::::::::TH:Y:::V::C::::::::::::::::::::::::
Hmu2649         ::::::L:::R:::A:::::::::TTE:Y:T::::::T:VV::::::::::::::::S::
hla1940         ::::::L:::A::SQ:GS:::::::SS:Y:::V::T::::V::::::::::::::::S::

consensus       TARWSTVWGLFFILLLYWSAPAFAAFGTDLY-ASQYGPTYAADGGMSGAAGDVIVVLAAQ
#oth            1..1.11......21..111..2....11.13243322211121..1211211.....1.
rrnAC3226       V::::C::::::::::::AS::M::::V::FQTTTGASA:::E::::::E::::::::::
HVO_A0154       :::Q::::::::::::::::::L::::V:::D:::::::F::N:::::GE::L:::::::
Hbo3749         :::Q::::::::::::::::::L::::V:::N:::::::F::N:::::GE::L:::::::
NP5136A         V::::CT::::::A:::L::::::::::A::::D:V:AV:G-:P::TA::A:::::::::
Hmu2649         :::::::::::::C:::L:::::::::::::::NEI:AV:G-:P:::S::::::::::T:
hla1940         :::::::::::::CI:::::::::::::::::SQNVN:::G-:P::T:::SE::::::::

consensus       LANLPTWFVGLVAAGGIAAAIATTAGLFIAASSAISHDIYTNIINPDATQRQQVLVGRLS
#oth            111..1....1..1.11...1..1.....11...11....2211.1.......121..21
rrnAC3226       F::::::::::::::AM::::::::::::T::::VA:::::ELV:::::::::::I::GT
HVO_A0154       :S:::::::::::::::::::::::::::T::::V:::::::::::::::::::F:::AT
Hbo3749         :S:::::::::::::::::::::::::::T::::V::::::::V::::::::::::::AT
NP5136A         ::::::::::F:::::::::V:::::::::::::::::::A::::E::::::::I:::::
Hmu2649         ::G::E:::::::S::::::::::::::::G:::::::::KGL:::::::::::::::::
hla1940         :S:::E::::F::::::::::::V::::::G::::::::::::::E:::::::IF:::::

consensus       IVALGAIVTLTALDPPALIAALVAYAFSLAAIVLFPMFFLGLWWENTNRQGALAGMSTGL
#oth            .112.312132.11.212111..32..1..12.........1...11.........22.1
rrnAC3226       :IGM::L::V::FN:::::GE:::::::::GV::::::::::::::::::::::::VL::
HVO_A0154       :::::I:::V::F:::::VGE:::L::::::::::::::::::::::::::::::::V::
Hbo3749         :::::L:::I::F:::::VGE:::L:::::::::::::::::::::::::::::::TV::
NP5136A         :::I:VLSIAF::::Q:P:::::SF::A:::::::::::::::::K:::::::::::::I
Hmu2649         :::::V:T::A::::A:P:::::T::::::GS::::::::::::::::::::::::::::
hla1940         ::::::LT::A::N:ASS:::::G::::::GS:::::::::M::::A:::::::::T:::

consensus       TLWVIPMVNDLIPHFIGLL-AAAG-G------LAQWVPAIGAALIGTPLVFIVTIAVSLA
#oth            22.42222.3332312122423224223222221222.1..1..123.1..2...1..11
rrnAC3226       LI:ITSII:SVL:SY::A:G::::E:GALVPIY::Y::P:::::::::::::::::::::
HVO_A0154       ::::AAV:::::F::SD:-:----:-::::::F:EF::::::::V::::::V::::::M:
Hbo3749         ::::AAV:::::F::SDA-:----:-::::::F:EF::::::::V:::::::::::::::
NP5136A         V::F:::L:E--GQ:-::VNGG::W:IEV::::ST:M::::S::::V:I::A:::V:::V
Hmu2649         VV:L:::::EVV:SY-:::AG:::SDGVLSAT::::L::::S::VAA::::V::::::M:
hla1940         :::S:::I:QIV:TY::S:E:PLSA:::::::::::M::::S:::TL:I:::::::::M:

consensus       TDEPPLETKKMVRQCHSPEPMGQQQTAEDVVSDA------------------GGQTPADD
#oth            .21.1321.21.......1...1121.11..445411111111111111111214212..
rrnAC3226       :P::::::::::::::::::::::E::A:::G:ST:::::::::::::::::S:S:::::
HVO_A0154       :::::ERI:::::::::::::::::S:::::MS:D::::::::::::::::::::S::::
Hbo3749         :::::QRI:::::::::::::::::S::::::TD::::::::::::::::::::::::::
NP5136A         :ED::KK::M::::::::D:::KDV::AE::ERRMEE:::::::::::::::R:DA::::
Hmu2649         :E:::::::R::::::::::::::::::E:::--:::::::::::::::::::AE::G::
hla1940         ::::S::::RI:::::::::::::E::::::A:GGEEVATDGGRAADDAGAD::RAAD::

consensus       -----
#oth            11111
rrnAC3226       :::::
HVO_A0154       :::::
Hbo3749         :::::
NP5136A         :::::
Hmu2649         :::::
hla1940         AATEE