[IQR] (FabG) COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 6 genomes BUD1581 6 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2632 pNG7072 - Hbo1101 - Hut1011 - NP0502A HQ1461A

Pairwise sequence scores
Consensus score	1854	pNG7072	HQ1461A	Hut1011	NP0502A	VNG2632	Hbo1101
1082	pNG7072	1666	1286	845	777	827	863
1133	HQ1461A	1286	2645	941	869	789	899
1401	Hut1011	845	941	1839	1212	1172	1205
1394	NP0502A	777	869	1212	1855	1209	1281
1409	VNG2632	827	789	1172	1209	1888	1339
1485	Hbo1101	863	899	1205	1281	1339	1877

350 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
pNG7072         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ1461A         MLTLARCLLFASHVGHTLFPAWADTNTRTATFRALGYSRVRASAPTIIRTSYWTKMFTSG
Hut1011         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0502A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG2632         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1101         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       --------------------------------------------MLSPDLDGRTALVTGS
#oth            111111111111111111111111111111111111111111112231322122211111
pNG7072         ::::::::::::::::::::::::::::::::::::::::::::----------------
HQ1461A         CDGAYTRSEYRGTASVSSITIEIFISRCQVTDIHSPNITAMADIN:T:T:::::::::::
Hut1011         ::::::::::::::::::::::::::::::::::::::::::::::::T:::Q:::::::
NP0502A         :::::::::::::::::::::::::::::::::::::::::::::::::CA:::::::::
VNG2632         :::::::::::::::::::::::::::::::::::::::::::::HA:::A:::V:::::
Hbo1101         ::::::::::::::::::::::::::::::::::::::::::::::::Q::::V::::::

consensus       ARGVGRAVALALADAGADVAVHYRTSEEAAAETAAEARELGV-AATTVQADVTDPDAVDG
#oth            132211341.31.12..1..11.21.421.322.13..241112121.31.1.3112..4
pNG7072         -------ML:E::A:::::::::::::::::::::D::DH:::E::::EG:::E:::::S
HQ1461A         :KR:::E:L:::::::::::::::Q:G::::A::ET:::YD::::::::::::V::E::T
Hut1011         ::::::E:L:::::C::::::Q::::P:E:EVV:EA:::A:::E:L::::::::::S:::
NP0502A         :::::::F:::::::::::::::N:::A::EA::E::::RD::D:VA:S::I:SEE::::
VNG2632         :::L::GL::S:::C::A::I::H::AD::D:A:::::A::AP:V:::RG:::S:::::H
Hbo1101         :H:::::I::RA:AS::A:::::H::DD::R:A::::::::AP::::::G::::::S::A

consensus       LFDAVEAELGPVDILVNNVGAFAPGRWDEIDLATWRRVIETNLYGTYLCSKRALPGMRAA
#oth            31232.23.131.2...1..211141.3111431.313311112213.12111.33..34
pNG7072         ::SDC:S:::D::::::A::PLPQ:::::LS:DE:KTAV:GC::S:::::Q:::LS::::
HQ1461A         MIARC::::DTI:::::A::PLPQ:::::LS::E:::T::GC:::::::TQAV::T::DT
Hut1011         ::::::ER::S::V::::::::::D::::L:Y:::QT:M::::DA:::::::::::::K:
NP0502A         C::TI:ET::::::::::::D:::EH:AD::IE::::::::::T::M:::::::GP::GS
VNG2632         I::T:::D:::::V::::::::::TH:T:::AD::HT:LD:::TAPF:TA:::::::::R
Hbo1101         M:::::::::T::L::::::D:::VH:E:::FG::K:I::::F:::V:::::::A:::DQ

consensus       GWGRIVNVGYADAEKALVVPKNFPYFAAKKGVLMFTRMLAADTQDDGITVNAVSPYVVEN
#oth            31...1.2.1.31122214.2.....1..311.2...11.1..21111.1.....11.21
pNG7072         :::::I:F:V:::RDDRA::M:::::::::A::Q:::T::Y:::::E::::::::FA:::
HQ1461A         H::::I:F:V:::RDDRA::M:::::::::A::L:::TV:Y::::N:::::::::FA:::
Hut1011         :D:::::::::SS::G::S:::::::V::A:::::::::::::SE:::::::::::::::
NP0502A         E::::::::::A::R:A:A:::::::V::T:::::::::::::T:::::::::::::::T
VNG2632         S::::::::::S:::G::N:T::::::::Q:L:::::::::::::::::A::::::::Q:
Hbo1101         S::::::I:::GS:::::Y:::::::V::T:::::::::::::::::V::::::::::DT

consensus       SDEFPEDAPRGRWATFEDIAAAVLFFCDDDSGYISGENVEIDGGWLPEAV
#oth            12211233....2.422.233222..233113.1..2.1211..1.1.42
pNG7072         TVVDVSEF::::A:::::V::PI::::S:AAA::::Q::A::::R:Q::-
HQ1461A         TVVDVSGY::::P:R:N:VI:PI::::T:AAE::::Q:IA::::R:Q::-
Hut1011         :A::::EL::::P:H:::LLQ:::::L:P::D::::A:::VS::::::R:
NP0502A         ::A:::T:::::::APD:LVQ:M:::V:E:::::::::I:V:::::::S:
VNG2632         :::::A:::::::::V::::GV:R::::A::::V:::::NV:::::::H:
Hbo1101         ::::::::::::::SV::::H::A:::HE:::::::::::::::::::TL