6 genomes BUD1633 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG5176 VNG5182 - - - Hmu2053 Hmu3339 Hut1357 hla1998 hla2094 NP6056A HQ2607A

Pairwise sequence scores
Consensus score	958	Hmu2053	VNG5182	Hmu3339	HQ2607A	Hut1357	hla2094	NP6056A	VNG5176	hla1998
567	Hmu2053	965	483	452	424	419	453	466	360	315
759	VNG5182	483	953	815	765	408	505	504	270	275
793	Hmu3339	452	815	958	893	414	489	503	268	303
753	HQ2607A	424	765	893	971	400	454	479	253	288
514	Hut1357	419	408	414	400	917	604	589	249	273
627	hla2094	453	505	489	454	604	955	773	246	249
645	NP6056A	466	504	503	479	589	773	962	259	257
326	VNG5176	360	270	268	253	249	246	259	902	387
345	hla1998	315	275	303	288	273	249	257	387	1050

153 symbols
consensus       --ASSTERLQRYLADELGECCDEDVCQRLDELEELDAAAGGPALEADLDVLSALANETRY
#oth            1335633234343521422.232215412532334454353434441143.112211...
Hmu2053         :M:EQSD::E:L:TR:::::::G::ED:VESI:SHA:TIPSDP-::::AA:AT:S:D:::
VNG5182         ::M::::::::::T::R:G:G::E:A:::::::::::::::::::::VG:::::::::::
Hmu3339         ::M:::::::::::::R:G:G::E:::::S::::I:::::::::DE:VEL::::::::::
HQ2607A         MYM:::::::::::::G:G:G::E:::::AK:::I:T:::::::NE:VEL::::::::::
Hut1357         ::----------ME::::::RN:::QA::E:IAS:ERTI-DEQ:SVE::::A::::::::
hla2094         :M:QA::::::::D::::::RS:::DR:::::ST:E:GL:TAQA::E:::::::SS::::
NP6056A         :M:QT::::::::S:::::::S:::E:::N:::T:GD:LATEQIASE:::::::::::::
VNG5176         ::-MVQDATADGVM:ASDA::AP------------PGNVDSD:MAT::Q::::MG:D:::
hla1998         MTDKLSSAEPNEGSTAQRG::AG-----------V:HSLSDRD::V:VET:A:VGS::::

consensus       KIVRILHAAEEELCVCELAPLVDVSESAISHALSQLTDAGLVTRRKDGRWRKYRATARAE
#oth            423.423213212.1.1241313.12112.11..4.4411.2421.1.3.11.32.4125
Hmu2053         R:A:L:S::D:::::::IS:V:::::::::::::D:RE::::S:::::T::Y:E::::TT
VNG5182         ::I::::I:G:::::::FS::L:::D:::::S:::::E::::::::::K::::QT:M:GD
Hmu3339         :::::::I:G:::::::F:::L:::D:::::::::::::::I::::E:K::::::::::N
HQ2607A         :::::::I:G:::::::F:::LE::D:::::::::::::::II:Q:E:K::::::::::S
Hut1357         TLA:A:V::R::::::::Q:::A::::GL:::::E:AAS:::ES::::::K:::::N::V
hla2094         TL::V:V:::::::::::NAV:::T::GL:::::A:VN::::EG::::::K:::::N::T
NP6056A         T:I:V:V:::::::::::NAV:::T::GL:::::::V::D::DG::::::K:::::N::V
VNG5176         ELL:RIAN:DDGV:::D:EAT:G::Q::V:Q:::R:YT::::::::E:S::Y:EP:ETT:
hla1998         GAL:LVA:S:GGT:G:::E:ALG::QG:V:Q:::R:Y::::L::::E::::Y:D::G:::

consensus       ALLTALDGSRSL---------------------
#oth            22253.222146532222122111111111111
Hmu2053         :::S:::ET:GEV::::::::::::::::::::
VNG5182         :::V::N:::R-:::::::::::::::::::::
Hmu3339         :V:I::::::E::::::::::::::::::::::
HQ2607A         :V:V::::::E::::::::::::::::::::::
Hut1357         :IV:V:E:TVAVEPASNGDSQ::::::::::::
hla2094         ::I:V:E::V:TDE:::::::::::::::::::
NP6056A         ::V:L:E::V:TDA:::::::::::::::::::
VNG5176         V::ET::DL:GNHE:::::::::::::::::::
hla1998         R::AL::ET::AGETGSADERRSTDEIEAGSQS