5 genomes BUD1691 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0132 HVO_2536 Hbo2325 Hmu2531 - hla1581 - -

Pairwise sequence scores
Consensus score	3133	rrnAC0132	Hmu2531	hla1581	HVO_2536	Hbo2325
2740	rrnAC0132	3260	2726	2295	2365	2381
2665	Hmu2531	2726	3079	2243	2304	2299
2543	hla1581	2295	2243	3239	2377	2258
2704	HVO_2536	2365	2304	2377	3150	2666
2673	Hbo2325	2381	2299	2258	2666	3394

466 symbols
consensus       MTVSRTVELEGHIIDSGMMQQCFGIVMDLGGSFDVEQFDVGRHKDDESYCRMLVEADDEA
#oth            .132.1..11.......11.311.21.....1.3.13.11.121122..1.13.2.1122
rrnAC0132       :::::E::::::::::::::S::::I:::::::S:QK::I:::::E:::A::::::::::
Hmu2531         :::::E::::::::::::::T::::I:::::::T::T::I::::T::::A:L::::::::
hla1581         :SH:::::I::::::::T::R:::A::::::::::::::::K:E:V::::::A:S:::PE
HVO_2536        ::FT:::::D:::::::::::AM::::::::D::::::::::Q::EP:::::S:S:::RE
Hbo2325         ::AI:::::::::::::TL::A::L::::::D:E::E:N:::S:T:T:::::D:T:ET:D

consensus       TLQEILHELHQNGANLTDPKDATLEAAPADQVVPHGFYSTTNHPTFVRYDGEWIEVEDIE
#oth            2..2.1.....2.1113112.131121.1.2...21.........311121..23.221.
rrnAC0132       Q::S:V:::::H:V:PS:::::::VP::D:::::::::::::::::I:H:::::::::V:
Hmu2531         :::S:V:::::::::PA::::V:::P::::::::::::::::::::::::D::LA:QNV:
hla1581         :::A::::::::::V:EN:T:VE:V:::::K:::PN:::::::::E:L::::::D::R::
HVO_2536        :::::::::::I:::::::V::RV::S:::R:::V::::::::::D:::Q:::LP:::::
Hbo2325         D::::::::::I::::::AV::HV:R:::::::::::::::::::K:::E:::V::D:::

consensus       MDCAIVVEE-------------------PDDGPRAYTKVLNAIEEGDLVVTDEAGIRVAP
#oth            ....21123111111111111111112223121..1.....11.21.211.112..214.
rrnAC0132       ::::V:::DGDASEAQRASEQPSGGDET:R:::::::::::::::::M:::::T::K:Q:
Hmu2531         ::::V::DT:::::::::::::::::::--:E::::::::::V:A::QI::G:T:::I::
hla1581         ::::LI::P::::::::::::::::DGG::GD::::::::::V::D:::A::QS::::N:
HVO_2536        ::::::I:::::::::::::::::::::T::::::S:::::G::::::::::::::::K:
Hbo2325         ::::::IK::::::::::::::::::::TE::T:::::::::::K:::::::::::H:D:

consensus       PERPRDSGGAFGFMQGGVSSERPSESTIREVAEAIEETKADGGKVLVVAGPALIHSGAGD
#oth            .....232.1................1.121.1121.1233..1111.1...1..1.111
rrnAC0132       :::::::::::::::::::::::::::::KI:N::::::KE::::MA:C:::::::::RE
Hmu2531         :::::GQQ:::::::::::::::::::::QI:::::::R:::::I:A:C:::::::::RE
hla1581         :::::SG::::::::::::::::::::::::::ELR:VTEA::N:M::::::V:::::::
HVO_2536        ::::::AS:P::::::::::::::::L:E:::::LR:::::::N:::::::::::::G::
Hbo2325         :::::::S:P::::::::::::::::L:E:::::V::::SQ::::::::::::::A::::

consensus       DLARLVREGYVDMLSAGNGFATHDIERDLYGTSLGMDMETLEHPRKGHKHHIYTISEVIR
#oth            1..2..11..1.11.......1..1..21......1.2.111.1.1......1....1..
rrnAC0132       :::::::::::::::::::::V::::::I::::::::T:S:D:::H::::::::::::::
Hmu2531         :::Q::::::I::::::::::V:::::::::::::L:T:S:D:A:::::::::::::I::
hla1581         A::E::EA::::A:::::::::::L::S:::::::::V::::::::::::::W::::I::
HVO_2536        A::E:::::::::I:::::::::::::G::::::::::::M:::::::::::::::::::
Hbo2325         :::::::::::::I:::::::::::::G::::::::::::M:::::::::::::::::::

consensus       AGGIEEAVEEGLIESGVMYECVQNDVPFVLAGSIRDDGPLPDTITDAVEAQNAIREQAHE
#oth            1...11...2.2.31.1..1.131.112..................11...1...1...3
rrnAC0132       E::::::::S:T:::::::::ID::R::::::::::::::::::::::::::::::::::
Hmu2531         E::::A:::S:T:D::::::::T::R::::::::::::::::::::::::::::::::::
hla1581         :::::A:::D:I:GE::::Q::::::DT:::::::::::::::::::::::::::D:::D
HVO_2536        ::::A:::::::::::::::::KH:::Y::::::::::::::::::TI:::::::::::R
Hbo2325         ::::A::::::::Q::I::::::::::Y:::::::::::::::::::::::G:::::::K

consensus       ADMVLMLSTLLHSVAVGNCLPSTTKVVCVDINPATVTQLLDRGSAQAVGMVTDIGTFVPT
#oth            ..1....1...............111..................1..1...........2
rrnAC0132       ::::::::::::::::::::::::R::::::::::::::::::::::::::::::::::I
Hmu2531         ::::::::::::::::::::::::R::::::::::::::::::::::::::::::::::L
hla1581         ::I::::A:::::::::::::::::T::::::::::::::::::::::::::::::::::
HVO_2536        :::::::::::::::::::::::A:T::::::::::::::::::S::I::::::::::::
Hbo2325         ::::::::::::::::::::::::::::::::::::::::::::S::I::::::::::::

consensus       LAEQVL-------EGDEA-D-N------------------------
#oth            ..12111111111222123232222222221211111111111111
rrnAC0132       ::::L::::::::--S:E:-:-::::::::::::::::::::::::
Hmu2531         ::::LV:::::::--::::-:-::::::::::::::::::::::::
hla1581         :::F:::::::::::E::GANDEAAITEDSDA::::::::::::::
HVO_2536        :::K::::::::::A:DDN:D:::::::::::::::::::::::::
Hbo2325         ::DK::GENTATDG:EDDA:G:RDTGSHRGDGHGDGGSPGGHCPGR