5 genomes BUD1850 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC1920 HVO_2180 Hbo1894 - - hla2038 - HQ3080A

Pairwise sequence scores
Consensus score	1676	HVO_2180	HQ3080A	Hbo1894	rrnAC1920	hla2038
1106	HVO_2180	1680	834	936	965	927
1160	HQ3080A	834	1777	1145	999	994
1238	Hbo1894	936	1145	1832	1046	1045
1311	rrnAC1920	965	999	1046	1666	1087
1313	hla2038	927	994	1045	1087	4121

562 symbols
consensus       ------------------------------------------RPADPAEARR--------
#oth            111111111111111111111111111111111111111121434322343111111111
HVO_2180        ::::::::::::::::::::::::::::::::::::::::::M:TVSSDLLD::::::::
HQ3080A         ::::::::::::::::::::::::::::::::::::::::MPTRRL:::IA:::::::::
Hbo1894         ::::::::::::::::::::::::::::::::::::::::::VSFI:P:V::::::::::
rrnAC1920       ::::::::::::::::::::::::::::::::::::::::::--M:T:SF::::::::::
hla2038         VSISRLTTRRTDERSRRGRRNRPHRGPDPRRHRRRRRSQHRP:::::PQ:G:GRRRAGDT

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HVO_2180        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3080A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1894         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1920       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2038         RQRRHHRPSDEELRPLGPQAGRSAGAEGGRRGVRLRGSRPRGRAPERRRGDLRRDRGELP

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HVO_2180        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3080A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1894         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1920       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2038         HGRHHRDHRRGRPEPRAVPLQDARRTSGVAEDRGRTDGDRLRPRGARAQQRGALAARRGV

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HVO_2180        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3080A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1894         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1920       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2038         LDPGRRRLPRLEPRAGRDRAPLRASRSHCRRDAVARHRGHSRTRARRGALPRVLRRLPRG

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HVO_2180        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3080A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1894         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1920       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2038         HRPARTPPRQERAVGAPATRARAPDRTRDSLAARHVPQGQREAGTRRPPRGEVRRTRLPP

consensus       --------------------GVRDVAPLLLGIIPFGLVAGIAAVNAGLGLAQAVGLSVVV
#oth            11111111111111111111.1.112.112..2.......2.1.11..2223.2.2.11.
HVO_2180        :::::::::::::::::::::::AAG::Q:::A:::::::V:::EQ::SV:H:L:F:S::
HQ3080A         :::::::::::::::::::::L:::::::I::::::::::A:::E:::RPL::I::::::
Hbo1894         :::::::::::::::::::::::::S:I:V::::::::::V:::::::SPL:::::::::
rrnAC1920       ::::::::::::::::::::::::::::::::::::::::::T:::::::PA::::::::
hla2038         RVTVDGDLLDGNSFDGDIWA:::::S::::::V::::::::::::::::::E:::M::I:

consensus       FAGASQLAAIELLGQNAPLAVVVGTAVVINLRMLMYSASIAPHFRDFRARWKAGLAYVLT
#oth            ........311.1.21.2.31.13.1....1.32........2.23324.21.431.1..
HVO_2180        ::::::::M:::::AD::::I:::::::::::TM::::::::Y:::LT::S::LAS:L::
HQ3080A         ::::::::V:D::::::A:SI::I:G::::::I:::::::::S:QS::P::::IT:::::
Hbo1894         ::::::::I:D::::::E:V::FV:::::::::M:::::::::::RV:S::::VSS:L::
rrnAC1920       :::::::::L:::::::::T:::A::::::::L:::::::::Y::N:TG::::M::::::
hla2038         ::::::::::::I:S:::::::::::::::V::V::::::::::A:YGR:LR::::::::

consensus       DQAYALSIARY------ERDSETDRRRYYLGVAATLWIVWQVCTVAGALLGAGVPDAWGL
#oth            .....1.11212111113233222.33..121121..3...12.12.222.221.11..1
HVO_2180        :::::V:::::::::::G::G::::FA::V:AG:S::L::::T::::::::S:L:PE::F
HQ3080A         ::::::::S::AE::::KEL:K:E::::::T::L:::::::I::IV:III::R:::E:::
Hbo1894         :::::::::::NEGAPA::PNSNE::N:::A:::S::::::::::L:I:::T::::::::
rrnAC1920       :::::::V:S:::::::RS::::::KW::::::V:::A::::T:I::::::T::::::::
hla2038         :::::::V:EF::::::::NP:RS:W:::::A:::::V:::IA::V:VVV::S:::::::

consensus       EFAVPLVFLALLVPAAKDRPTAAAALVGGAVAVVG-V------AGLPLNLGLLTGAVVGV
#oth            3..2.....11...2432113411121..41112232111111212.11.11121133.1
HVO_2180        D::A::::::::::TL:::ASG:SC::::L::TGVV:::::::::V:FH:DIIVA:::::
HQ3080A         G::::::::S::::::AS::AI:::::::V:ST::TI::::::YNF::::::I::GAT::
Hbo1894         ::::::::::::::SVSN::RLV::V:::G:::A:E:VVVGGSP:::F:::::L::LA::
rrnAC1920       :::I::::::I::::IE:AA::V::A::::I:::::-::::::::::::::::VA:G::I
hla2038         T::::::::::::::M:::::T:::VA::TI:::A:-::::::::::::::::::::S:I

consensus       LAGVATDSAGGDA---------
#oth            21.1222341343333221221
HVO_2180        :::L:V::L:::::::::::::
HQ3080A         V:::VV:TYTNTPGQSSSETNH
Hbo1894         :::::AAAI:DE:VETEEEVSH
rrnAC1920       T:::L:E::T:GTDGD::::::
hla2038         :V:LL:EVF:E--:::::::::