5 genomes BUD1865 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1043 Hbo0538 - Hut2122 hla1303 - HQ2371A

Pairwise sequence scores
Consensus score	1522	HVO_1043	Hbo0538	HQ2371A	Hut2122	hla1303
996	HVO_1043	1515	883	709	781	764
956	Hbo0538	883	1598	671	724	775
997	HQ2371A	709	671	1530	829	930
1139	Hut2122	781	724	829	1512	932
1138	hla1303	764	775	930	932	1704

214 symbols
consensus       ----------------------SMTDDDWAAAIREQRAAKDRYFADDPRSPLPAAAR-ES
#oth            122222222222222222222322222113231322.44.222113232..212441123
HVO_1043        ::::::::::::::::::::::-::::A:LD:L:TH:EQ::::L:G:RN::V:PDQ:::V
Hbo0538         :VNAAQTATAFKSFRDVRARMG:PDTEA:RE:LLTH::H::EF:::::Q:::S::D::::
HQ2371A         :::::::::::::::::::::M:T:P:::Q:E:N:S:TN:E:::RSSD:::V:PEF:G::
Hut2122         ::::::::::::::::::::::-:::Q:Y:ER:::::DE:ET:::EH::::I:QH:E:--
hla1303         VAPISPDEIVIAQNAQYKRMTETTP::::::Q:EA::R::HEH:R:SA::::::SM:GDA

consensus       FDGLAYFDPDPDYRFELELDEHDDKETITVETTADGEQEYRRWGEFAFEIAGESVTLDAY
#oth            .2..21132.131.2222.312.21.21.12.11..112.22113.431241231312..
HVO_1043        ::::D:::::::L::::::R:Y::P:R::IG:ST:::R::LA:AR:E::VH:::YA::::
Hbo0538         ::::S::E::QS::IVT::::Y:T::::::S::T:::RD:LV::S::::RN::::R::::
HQ2371A         :P::::YSI::E:::TVP:TRD::P:::::::::::::T:::V:T:DITVETTP:SIA::
Hut2122         :A::DF:AV:::::Y::S::::::::SV::::::::S:::V:::::SV::::QD:::Q::
hla1303         :P:::::::::A:::VVP:H:::E:::V::::::::::T:::::::RL::D::T:::Q::

consensus       RPTDGEDRLWVPFRDETSGEETYGAGRYLDLEPDRDRTDDGTWVLDLNYAYNPTCAYNEA
#oth            2233223.1......2.2121.......1...2331232.23.21.2.3....1...122
HVO_1043        :ADAD:G::::::::::NA:::::::::::::AA-::::::R::V:F::::::F:::SPR
Hbo0538         :SEPESN::::::::::::D::::::::::::DPD::EG:A-::::F::::::F:::::Q
HQ2371A         E::::S:::::::::A:::S::::::::I::::TE:HN:::::T::::R:::::::::P:
Hut2122         K:AS::E::::::::K:C:::::::::::::::::HQ:G:E::I::::L:::::::::::
hla1303         :::::A::F:::::::::::T::::::::::::::::V-::E::V:C:V:::::::::H:

consensus       YECPLVPMENWLDVRIEAGEKDFPGE--GHDAD-
#oth            .....1.1....212111...3112311332421
HVO_1043        ::::::::::::E:::::::::YE:P:::GGGE:
Hbo0538         ::::::::::::N:P:R::::T:E--::-----:
HQ2371A         :::::::A::::::P::V:::::::N::F::D-:
Hut2122         :::::I:::::::I:V:::::AY:::TI:::T:H
hla1303         :::::I::::::::A::::::K::A:::PAG::H