5 genomes BUD1875 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_0430 Hbo1076 Hmu0350 - - NP0772A HQ1375A

Pairwise sequence scores
Consensus score	1044	Hbo1076	HVO_0430	HQ1375A	Hmu0350	NP0772A
668	Hbo1076	1050	542	486	407	407
688	HVO_0430	542	1119	435	411	416
619	HQ1375A	486	435	1045	392	419
600	Hmu0350	407	411	392	962	439
609	NP0772A	407	416	419	439	987

152 symbols
consensus       MHTDARDALVARLSSYDAAVEVGVGRRPSVAAALAARGVDVTATDVHSCDVPRTVAFVRD
#oth            23344321114211312421.1.1.11.3..21.242.111111.123221.4314.13.
Hbo1076         VE:VV:::::::::Q:ETVT:I:::::::::V:::DA:C:::V:::::F:L:SELH::A:
HVO_0430        VKKSL:::::GQ::G::R::::::::E::::::::::::::V:V:::DFP::DG:S::::
HQ1375A         ::SL:Q::::E:F:::TS:::::I:N::A:::::VSC:::IV:::IV::P::P::T:AY:
Hmu0350         ------------:ADFECV:::::::::D::RR::R::::::V:::VRR::::AL:::L:
NP0772A         ::::SEG:::D:::::::L::::::N::T:::::DE::CR::::::DT:A::G::R::::

consensus       DVV--SDDPDPGPYADAEAVYALNCPPELHRPARDVARRVDADCLFTTLGGDAPAVPCDR
#oth            .1233223312222231221....2.1..1..2231.3321.2121....2.414.2242
Hbo1076         :::VA::RD::::AYH:D:I::::L::::::::::::AA:::EF::::::F:S:T:::ET
HVO_0430        ::FARA:AA:L::::A::V:::::V:V::::::AE::::A:::F::::::Y:E:S::VS:
HQ1375A         :I:TT:EQRA:DSVY:V:L:::::L:::::::F::::DT:G:::RL::::Y:::I:::HP
Hmu0350         ::-::-T::::SV:::::::::::::::::::L:AL::EHG:V:Y:::::::Q:::AV::
NP0772A         ::-::-T:::VSV:SG:G:::::::::::Q::LVSL:S::::::::::::::PTL:DATP

consensus       ESLP-GGETLYVVEAGRR--------------
#oth            12111121...322433432211111111111
Hbo1076         :TIAD:A::::::P:::KE:::::::::::::
HVO_0430        :::::-::::::A:R:::DQRARRDSPGRSQE
HQ1375A         V::::::::::I::SESS::::::::::::::
Hmu0350         :Q:::::::::R:RQDGPKGK:::::::::::
NP0772A         :T:::-TQ:::HYP----::::::::::::::