[E] (GloA) COG0346 Lactoylglutathione lyase and related lyases 5 genomes BUD1890 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0595 - - Hbo4061 - - hla0489 NP3948A HQ1123A

Pairwise sequence scores
Consensus score	1591	NP3948A	Hbo4061	HQ1123A	VNG0595	hla0489
1033	NP3948A	1571	820	811	887	858
1065	Hbo4061	820	1610	882	916	956
1202	HQ1123A	811	882	1576	1104	1121
1338	VNG0595	887	916	1104	1571	1153
1308	hla0489	858	956	1121	1153	1594

211 symbols
consensus       MMDDTPAT---PVTADPPDSPFHTTGTDHVTIWGSNAADTIAFYRDLLGMPLVLRQPNLD
#oth            132223221112.1123.1112311.1..2112.11221..1..111...1..12.....
NP3948A         -:EH::EH:::D:::A::E::V::I::::M:VM:GD::S:::::::::::::::E:::::
Hbo4061         :T::QS::TDP:::::::E:A:NV::M:::S:I:::IE::::::::V:::S:::K:::::
HQ1123A         :V:N:D:::::S::::Q::::IQ::::::I::::::ET:::E::QE::::::::::::::
VNG0595         -:A::NS-:::::S::A:::::R::::::::::::::E:::::::::::::::M::::::
hla0489         :S::I::-::::::PER::A:::::::::::V::::E:::::::::::::::::::::::

consensus       DPSQTHLFFDTGDGRILTFFVGDGRASNRGR-RTGVGAVHHLAFSIAPDDFEDIMAALED
#oth            1.22...........1..1..313.41343111323.2....2.1211332.12221.12
NP3948A         A:EL::::::::::::::::::E::SPRPY::--:A:N:::::::::::S::ETKT::D:
Hbo4061         A:NV:::::::::::M:::::EE::E::T::L::P::G::::::RYD:ERL:E:R:G::E
HQ1123A         ::::::::::::::::::V::::-:Q:TQQQ::G:I::::::C::V::S::::V:::::A
VNG0595         ::::::::::::::::::V::N:E::::HD:L::Q::G::::S::::AA::::V::::D:
hla0489         :::::::::::::::::::::S:D:P:A::Q::A:T::::::C::VD::EY::::S::::

consensus       AGHGYNVFDRGIFHSLYTQDNNGLVIELATDKYDIPDERRGEVLALAQRLREADGADYAK
#oth            2.311.1....2.2.1..1.21..11..231.111.21.1..1..2.122.2211.2112
NP3948A         ::Y:F:E::::A::::::::PS:::V::VVE:::F:P::::::::::HEK:VEA::G:VD
Hbo4061         H::H::E:::::::::::T:H:::::::::::FE::::::::A:::::QK:LQA::E:::
HQ1123A         D:R::::::::V:F::::::::::I:::S:::::::A::::::::K::E::V::D:::::
VNG0595         :::::::::::::C::::::::::IV:::A:::::::D:::::::T:::I:::::::F:A
hla0489         ::K::::::::::::I::::::::::::SS:::E:::D:K:::::T::::::E::::F::

consensus       DRHMEAALEELGLDAEPADLPDAASGAGV--
#oth            12.12...21.21123342111.42.1.131
NP3948A         :E::Q:::S:::::S::RFEGS:PT::::E:
Hbo4061         AE:L:::::::D:PVKRKA::::Q::::GLN
HQ1123A         :K:LA::::A:NI::HAH:::::T::V:GIN
VNG0595         ::::::::D:::I:::::::::::T::::::
hla0489         :::::::::::::PVNKY:::::DA:V::::