5 genomes BUD1896 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1984 Hbo1852 - - hla1112 NP4432A HQ3094A

Pairwise sequence scores
Consensus score	2652	hla1112	NP4432A	Hbo1852	HVO_1984	HQ3094A
2370	hla1112	2690	2251	2144	2232	2187
2334	NP4432A	2251	2709	2148	2165	2150
2389	Hbo1852	2144	2148	2673	2258	2204
2456	HVO_1984	2232	2165	2258	2660	2395
2401	HQ3094A	2187	2150	2204	2395	2670

360 symbols
consensus       --MNPNE--LDDDV---------FTRDVDNPAARELREMLNEQDFVFAPGIYHALDARLA
#oth            1223121112222.111111111132.1..131121.23122.111....2.......1.
hla1112         :::Y:::::::::::::::::::::K:I::::G:R:::LFE:::YT::::::::::::::
NP4432A         :MAHD:D::GT:E:ASRVQNTESIV:::::::::::::KFE::::T::::L:::::::::
Hbo1852         MSED:Y:RTTGA:::::::::::::::::::S:::F:R::D::N::::::::::::::::
HVO_1984        :::::T:::::S::::::::::::AQ::::QK:::::::::T::::::::M:::::::::
HQ3094A         :::::T::::::N:::::::::::N::I:::QGEKF:NQ::N::::::::M:::::::I:

consensus       EMAGLDAAYMSGYSTVLGQFGFPDLEMVTMTEMVENAKRMVEATNLPVIADCDTGYGGIH
#oth            .1111.........................1........11......11.........2.
hla1112         ::::::::::::::::::::::::::::::S:::::::::::::::::::::::::::T:
NP4432A         :::::::::::::::::::::::::::::::::::::::I::::::::V:::::::::::
Hbo1852         :L:D:::::::::::::::::::::::::::::::::::I::::::::::::::::::V:
HVO_1984        ::T:H:::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3094A         ::T:H:::::::::::::::::::::::::::::::::::A::::::I::::::::::::

consensus       NVRRAVREYEKAGVAAVHIEDQTTPKRCGHIAGKQIISREKARARFEAAVDAKQSEDTVI
#oth            ................1.................2111112.21..2...........21
hla1112         ::::::::::::::::I:::::::::::::::::EVV:Q:Q::S::::::::::::::::
NP4432A         ::::::::::::::::::::::::::::::::::K:::::D:E:::S:::::::::::I:
Hbo1852         ::::::::::::::::I::::::::::::::::::::::D::::::::::::::::::F:
HVO_1984        ::::::::::::::::::::::::::::::::::::V:::::K::::::::::::::::V
HQ3094A         :::::::::::::::::::::::::::::::::::::P::::E:::T::::::::::::V

consensus       IARTDAYGSANGDWEEHLERGRIYADAGVDLVWPEMPDPSREDAVNYAETIHETHPDLKL
#oth            ...1.1...1....11.1....1.......2......1......12...1......1.1.
hla1112         :::I:S:::::::::D::::::::::::::::::::::::::::IE::::::::::::D:
NP4432A         :::::::::::::::::::::::::::::::::::::::::::::E::::::::::E:D:
Hbo1852         :::::::::S::::::::::::::::::::M:::::::::::::::::::::::::::::
HVO_1984        :::::::::S::::D::V::::::::::::I::::::N:::::::A:::E::::::::::
HQ3094A         ::::::::::::::::::::::M::::::::::::::N::::::::::::::::::::::

consensus       AFNYSSSFAWSEEEDPLTFQELGDLGYQYIFITLFGLHSGAHAVYEDFKNLAENDEEAQF
#oth            ........1.1211.1...1.......2......21......11...1221113..11.1
hla1112         ::::::::E:GAQ::::::E::::::::::::::Y::::::::A::::A:I:::::::::
NP4432A         :::::::::::::::A::::::::::::::::::YA:::::::::::M::IEQ::::::W
Hbo1852         :::::::::::K:::::::E:::::::E::::::::::::::S:::::RA:::T::::::
HVO_1984        :::::::::::::::::::::::::::K:::::::::::::::::::::K:::Q:::G::
HQ3094A         :::::::::::::D:::::::::::::K::::::A::::::::::::::K:::A::TG::

consensus       DLEGRYLDHPTESHHELSFVSRYQDIEAQFDPEARRRIEESEGFSEEESDPIT--SDDD-
#oth            1..3..12.1..........111.11.22..11.22.2.3.1..11.121.1111.1121
hla1112         :::E::IG:E::::::::::P:::::::::::D:S::H:::A::TD:::::::TE:N::D
NP4432A         :::::::G:E::::::::::::F:::::::::::KE:M:K:A::T::::::L:::::GN:
Hbo1852         :::::::::::::::::::::D::ET:M:::G:::N:::N:::::::::T::E:::::-:
HVO_1984        :::Q:::::::::::::::::::::::TE::::::::::::::::::QA:::::::N::D
HQ3094A         E::D:::E:::::::::::::::::::TK::::::::::Q:::::D::T:::::::::::