[R] (-) COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold 4 genomes BUD1930 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1918 - HVO_1086 Hbo0557 Hmu0363 - - - -

Pairwise sequence scores
Consensus score	1905	Hbo0557	Hmu0363	VNG1918	HVO_1086
1502	Hbo0557	1906	1305	1229	1208
1551	Hmu0363	1305	1897	1238	1165
1448	VNG1918	1229	1238	1908	1211
1431	HVO_1086	1208	1165	1211	1895

255 symbols
consensus       MNLDWDRITHVTKIDPAKRLPRDIDVLRHTDAVIVGGSDGVTAENTLAVIERIAAEFPDI
#oth            .321.2332.1..1...232.31231.32..11.........11.1.1221223322.11
Hbo0557         :D:N:::LS::::::::EHV:N:LEL:DG::L:::::::::::::::DAVQKVKSQ:::L
Hmu0363         ::::::D:::::::::::D:::::G::SE:::I::::::::::::::::::Q:GEAV:S:
VNG1918         :TI::GSV::I::V:::DP::D:AS::G:::L::::::::::ES::::T:::::T:A:::
HVO_1086        :SF::SEFE::::V:::::H:ES:::::::::::::::::::E::S:::F::LR:::::L

consensus       PVLQEPYRSSHVSKDTIDAVDALAVPAVYNGDRANFVRKHVDLFTEAARKPEELTGSGLP
#oth            .22....112...22.1121.3121...1...321..3..121..1212.12211.21..
Hbo0557         :::::::::::::SK:V:T::Y:S::::F:::D:H::::::E::::::S::D:V::::::
Hmu0363         :I:::::S:D:::T:::::::L::I::::::::EH::G::L:::::VGN:::::F:T:::
VNG1918         ::W::::SG::::::::E:::NV:::::::::S::::D::::F::Q:::::AQ:::AN::
HVO_1086        :LV::::::A::::R:VEVA::VF::::::::KT:::E:::GF:::L:::S:DV::::::

consensus       VVGDAIASKGRDAVARLADKIVGEGYVIQNCDSKAAAVSGVETAYTPEQVAGAALATESF
#oth            21.1322..11111331212121....1..31..1.2211.113..1.1.......1.1.
Hbo0557         ::::::S::A:E::SE::T::I:::::::::::::::::::::P::T:E:::::::A:::
Hmu0363         :L::L:::::L:::::M:::::::::::::IE::::T:::::::::T:::::::::::A:
VNG1918         L:::IVE:::::::TD:T:AVLA::::V::L::::::E:::D:L::::::::::::::::
HVO_1086        F::SVL:::::E----:V:GV::::::V::P:::V:GLTN::EH::::::::::::::::

consensus       YGFPIFYIEYSGTYGGPEDVEAAAQYLDDTTLLYGGGIRSRAQTREILDAGADAVVVGDC
#oth            11..1..2....1.1..21.2..122.1112.1.....32231121........11...1
Hbo0557         :::::::::::::::::T::A::S::::E:V:::::::ETHE::A:::::::::::::::
Hmu0363         :::::::L::::::::::E:::::SH:::A::V:::::N::RRA::::::::::II::::
VNG1918         FD::V::V:::::::::A:::::::::E::::::::::QNGT:::A:::::::::::::I
HVO_1086        ::::::::::::R:V:::::S:::PF::E:A:::::::::::::D:::::::::::::::

consensus       FHEDPERFRATIP--
#oth            ..1.111123.1.21
Hbo0557         ::D:::QY:Q:::::
Hmu0363         ::::::Q::::V:S:
VNG1918         :::::D::ID:::::
HVO_1086        ::::T:::LE:V:TT