4 genomes BUD1937 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG7019 HVO_B0142 Hbo2913 Hmu1859 - - - -

Pairwise sequence scores
Consensus score	2502	pNG7019	Hbo2913	HVO_B0142	Hmu1859
686	pNG7019	1090	471	528	506
1728	Hbo2913	471	2532	1292	1271
1886	HVO_B0142	528	1292	2550	1345
1745	Hmu1859	506	1271	1345	2527

348 symbols
consensus       MDDRTRAPPAARLVEALETRADEDAVDALERLATAPPADRKAALRALRDLADDRPSAFDG
#oth            .1.32332233212232123332212221221321213312311.312211222.22112
pNG7019         :::QPSG::ETEIATL::QGNEA:::A:::::S::G::TQQ:C::S:KAA::EQ:EL:::
Hbo2913         :::S:QSLS:DY:SDV:DES:Y::::EYV::FQSV:VDE:RE:::TI:S:LEH::::L:P
HVO_B0142       :::TR::S:LE:::::A:::T:DEVS:S:GE:L::S:E:::R:::E:::::N:::T::ES
Hmu1859         :V:::EP:EP:::::IV::EPV:RVR:::TA::A:::SV::D:V:::G:::::A::R:::

consensus       LLPALTSFLTDSERAIRLTTAKLFVAVAEAAPDAVAPAVSALAARLADEDEFYYVRARSA
#oth            22.1112..1.21.22..2...22.211.221111321.23.11.....1........2.
pNG7019         V::S::D::Q::G:PT:::::::V:TIS:G:::S:V:V:PT::E:::::S::::::::C:
Hbo2913         ::::::::::::::S:::R:::I::S:::N::L:AES:::P:::::::::::::::::A:
HVO_B0142       FM::V:P::::D:::V::L:::AL::::::DS:::::::::::E::::::::::::::::
Hmu1859         :A::VA:::::E::::::::::::::::::E::::LA::DD:G:::::::::::::::::

consensus       EALGYVALDHPDAVASPAVLADLRVGLSFDEPEVKAKLAKALECVALGDPGRLRHRVSAL
#oth            .......111....11.211.1..1..211221123111111231111212111132231
pNG7019         :::::::V::::::V::::V::::I::---------------------------------
Hbo2913         ::::::::EC:::::::EI::E::::::::AR:::E:::::::Y::::N::::::QL:S:
HVO_B0142       :::::::::::::::::::::::::::::::::::Q::::::::::::::::::::::::
Hmu1859         :::::::::::::::A:D:::::::::A::::::T:::::::AF::::::D::::L:EH:

consensus       AEHLDDESELVRYHLCTAAAAVGCECPEALAAVRGALAARLDDENPFVRGRAAEALGLLG
#oth            321222221111112212323211231231231221131212122221111111121322
pNG7019         ------------------------------------------------------------
Hbo2913         S::FA::::::::::V:T::V:::::::::VS:CA::T:Q::::S::::::::::::V::
HVO_B0142       ::::::GD::::::::::I:G:::DS:DS::::::::S:::V:::A:::::::::::::A
Hmu1859         GD:::A::::::::V:::LV:T:::H::R::D:::::::::::P::Y::::::::F:TV:

consensus       ------RDHGEDW--PNAALAALEADDAAFVAERAAFARAAERGDEAAAASDDD----DV
#oth            111111223323322132323123322321121133123223322323331333111122
pNG7019         ::::::-------::---------------------------------------::::--
Hbo2913         :::::::STVA::SP:::KI::::T::D:::::::R::V::LDD::NTTL:GG:NVTS::
HVO_B0142       GERGDR:::::SVAV:DS::G:ESDEA:::::::VG:L::SME::T:::::TVE::::G:
Hmu1859         ::::::A:VF:EY:::T:R:R::T:::ES::T::G:::LT::::RS:ERR:::G:::::L

consensus       GTIASIRRTTADAVDEITSPDAA--CPHCGIALPEAGPPMCPQCGAPY
#oth            112223121132223221221232211211321213211111211112
pNG7019         -----------------------::-----------------------
Hbo2913         :::Q:::E::D::::::::::S:::::N::L:::::::::::::::::
HVO_B0142       ::L:GV::::::::T:::::::EGV::::::D:A:GA:::::S:::::
Hmu1859         :::::L::::GSVIEAL:TA::VDD:::::T::::S:::::::::::R