4 genomes BUD1947 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0094 HVO_2732 Hbo2466 Hmu1246 - - - -

Pairwise sequence scores
Consensus score	4238	rrnAC0094	Hmu1246	HVO_2732	Hbo2466
3643	rrnAC0094	4213	3514	3100	3157
3599	Hmu1246	3514	4242	3014	3151
3533	HVO_2732	3100	3014	4196	3390
3632	Hbo2466	3157	3151	3390	4230

557 symbols
consensus       MTDH-EHYEAVVVGAGPGGAAAAATLARNGIETLVLERGVDAGSKNVSGGLIYAEESAPY
#oth            .1121.1...1...1......1...1.11.1........11..1......11.1.1...1
rrnAC0094       :::TA:K:::::::C:::::::::::::::V:::::::::::::::::::::::::::::
Hmu1246         ::E:::::::::::C::::::T:::::N:::::::::::T:::A:::::::V::::::::
HVO_2732        :S:Y::::::L::::::::::::::F:NY:::::::::::E:::::::::::::::::::
Hbo2466         ::E:::::::::::::::::::::::::Y:::::::::::E:::::::::I::G:Q:::V

consensus       TIDDLFPDFREEAAERPVTENYIHNIAGDRVESFDITDLHEHDTAWADAVLRRKMDSWLE
#oth            ...1...1..11.2...2.2121..1...1.111.121..1...1.1.1..........2
rrnAC0094       :::G:::::::::::::::::L:::::::::K::::G:::H::::::::::::::::::A
Hmu1246         ::::::::::A::T:::A:::::::V::::::::::SS::H::::::::::::::::::G
HVO_2732        :::::::G:::A:::::I:KYR:::::::K:::::L::::::::E:S:S:::::::::::
Hbo2466         :::::::::::::V:::::RY:L::V:::K::TM:L::::::::E:::::::::::::::

consensus       ARVHERTRETGGGLLTGVHVNGLLRD-RGEIVGVTTDELDPIEADIIVAADGVNSELARD
#oth            31...11.........2.1.1....112.1.1..112..1.12..211............
rrnAC0094       QQ::::::::::::::E:::T::::E::::::::::E:::::K:::::::::::::::::
Hmu1246         E::::M::::::::::D:R:T:::::::::::::E:A::::::::LV:::::::::::::
HVO_2732        :::::::::::::::::::::::::E:E:R:::::L::::::T:::::::::::::::::
Hbo2466         D::::MA:::::::::::::::::::GH:::I:::::::E:L:::V:I::::::::::::

consensus       AGLMDWDEPEEWFQGVKAVVDMPPEVINDRFDVAEDEGAAHLFSGDLFDGVRGGGFLYTN
#oth            ......11.1...........11112121..1211.1.1.........21..........
rrnAC0094       ::::::::::::::::::::::E:::::::::::S:D:::::::::::::::::::::::
Hmu1246         ::::::E::::::::::::::::::::DE:::IE::::V:::::::::::::::::::::
HVO_2732        :::::::::D:::::::::::::EAA:A::::::::::::::::::::E:::::::::::
Hbo2466         :::::::D:::::::::::::L:::TV::::ALE::::::::::::::SD::::::::::

consensus       RDSLSIGTVFHLDSIAAERAEPHELLDALLTHPLLAQWLGDDYDEREYAAKLVPDSKKAA
#oth            111..2........112.1........3......1....1.1.3.1..1.........1.
rrnAC0094       ES::::::::::::::E::::::::::S::::::M::::::E::::::S:::::::::::
Hmu1246         E:::::::::::::::D::::::::::N:::::::::::::E:E::::::::::::::::
HVO_2732        ::T::L::::::::LV:::::::::::G:::::::::::::::T:L::S:::::::::V:
Hbo2466         :::::V::::::::LV::Q::::::::::::::::::::D:::H::::::::::::::V:

consensus       HRSPHADRLLLVGDAAGQMQAQGPIIKGMNHAVTAGALAAEAFAQARSRNDPDQAGKLYA
#oth            112.132..1...............................11.2.12.13.32..21.1
rrnAC0094       :P:::E:::V::::::::::::::::::::::::::::::::::D::A:G::S::::::E
Hmu1246         :P:::K:::V::::::::::::::::::::::::::::::::::T::::GT:HD::E::E
HVO_2732        L:E::FG::::::::::::::::::::::::::::::::::SY:::K:::E:EK::IR::
Hbo2466         L:K:Y:E:::::::::::::::::::::::::::::::::::::::KG::K:::::::::

consensus       RKLRREGVMDKLRPRGYRLLRRLAERDPVTNLVDAVADSAVGRFGIRALS-GRLERLYAS
#oth            3..13....2....11.2221311.312.221122113.21..2111.12113...1131
rrnAC0094       K::HD:::::::::T:::VFGQ:G:LG::D::SN:I:E:::::::V::AA::L:::A:S:
Hmu1246         G::H::::::::::TS::T:G::::TG::AS::E:::::P::::AVS::GEDV::::F::
HVO_2732        ::::S::::K:::::::E:::GV::D:G::DV::T:LT:::::A::::::::::::::NV
Hbo2466         Q:::E::::S:::::::D:V:T:G:::D:::V::S:LS:RL::L::::::::G:::::G:

consensus       PRLAAIMPDTRTPYVTLPTVIAEELGERVTDENRVQPPDLEDRIGDLTYDTDVGNPHIEL
#oth            .1.3132...11....1.11......13121213.3..2.22...2....111.1...2.
rrnAC0094       :::VSMI:::KL:::::::::::::::P:::::T:S::::G:::::::::--::D:::::
Hmu1246         :::M:V::::::::::I::I:::::::Q::::::::::A:D:::::::::--::D:::::
HVO_2732        :T:S:L::::::::::::A:::::::T::REASS:T:::::A:::G::::::I:::::T:
Hbo2466         ::::::V:::::::::::::::::::THIAET:H:E::S::E:::E::::::::::::V:

consensus       RDNSFEASGAAVTACPVSAEDFGGGCYRDEMVRTNGSEEHVVSLDTQPCVECGTCAIVAD
#oth            2.3111...1..1......2........1.312...21.11...............1...
rrnAC0094       V:K::::::T::::::::::::::::::::::Q:::::::L:::::::::::::::::::
Hmu1246         I::G:D:::T:::::::::A::::::::::Y:E:::H:::::::::::::::::::V:::
HVO_2732        ::E:Y:::::::A::::::V::::::::E:V::::::::R::::::::::::::::V:::
Hbo2466         ::D:Y:::::::::::::::::::::::::FI::::EQ::::::::::::::::::::::

consensus       TDWEHPRGGKGVEFRDG
#oth            .2.2..2.1...1133.
rrnAC0094       :E::::A:::::::NQ:
Hmu1246         :H::::D::::::Y:E:
HVO_2732        :::S::::D:::::KW:
Hbo2466         :::T::::::::A:E::