[L] (PRI2) COG2219 Eukaryotic-type DNA primase, large subunit 4 genomes BUD1977 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2254 rrnAC2844 - - Hmu2874 Hut2352 - - -

Pairwise sequence scores
Consensus score	2699	VNG2254	Hut2352	rrnAC2844	Hmu2874
2021	VNG2254	2746	1703	1688	1687
2071	Hut2352	1703	2735	1792	1701
2254	rrnAC2844	1688	1792	2697	2012
2190	Hmu2874	1687	1701	2012	2772

372 symbols
consensus       MEPLHARYPFLAAARDAVEAAAVDLAEVVATDEAVVERARERVESAITDGTVGDPHR--R
#oth            .221.......331.2...1.2...121.12123112.11...11.111.11.1111111
VNG2254         :NAR:::::::GD::::::E:G::::R::TE:D::::::::::V::L::::I:E:AATVS
Hut2352         ::S::::::::D:S:Q:::::D::::T:::QRGPA:D:G:::::::LFE:::::T:::::
rrnAC2844       ::::::::::::RS:E:::::::::G:I:::::T:TA::L:::::::::::::E::::::
Hmu2874         :Q:::::::::QS::::::E:::::G:::::::V::::::::::W:::::S:::::::::

consensus       TRVELLSYPVARVLVSLVDQPVCTRKYAQAEAEAAYDRFTAEFAADTELKS-TDRERLDR
#oth            ....1........1..1113221111..2...11.21..111221322121121223111
VNG2254         ::::V:::::::::::I::ES:LV::::T:::D::::::::DEST::D:::VS:TT:VS:
Hut2352         :::::::::::::I:::I:::AL:HR::R::::T:H::::::L::G-:FR:::::QQ::L
rrnAC2844       :::::::::::::::::::VHI::::::::::::::::::E:::TT:::::::Q::T:::
Hmu2874         ::::::::::::::::::NT:::::::::::::::RE::VE::T:EDTFSY:G:S:S:SL

consensus       RTLLAEFDLTAAVHATG-------DRYRVDVGAYLALAADQRGDSWRLVNRALTDGEVPV
#oth            32..2..1.222.22221111111.22211.11..3..1221112......3.1..2.11
VNG2254         D:::S::::R:H::::P::::::::AHT:::PT::L::SSL:D:D::::::::D::R:::
Hut2352         :::::::E::GD:E:P:PGGLTDA::FA:::::::::::GE::E:::::::S::::Q::I
rrnAC2844       TE::G::::AS::SDA:::::::::G:::E:::::D:::::::::::::::P::::::R:
Hmu2874         SA::::::::::::E:A:::::::::::I:::T::E:::::W::E::::::T::::::::

consensus       TAEELNTLLRQAIRERIADGLPLAVPDAIADALDAEVAAIQEALSELDLTREIDTVVPEL
#oth            132..32.112.111.13....13..12...1.212.122123.2111..........1.
VNG2254         :DA::D::I:E:::::V::::::S:::Q::::::EP:::::D::AD::::::::::::::
Hut2352         DRG::LD:::V:VE:::L::::::::EP:::::AED:::VE:R:D:::::::::::::::
rrnAC2844       ::::::V::K::::H:VT::::FT:::::::E:T:::EQLE:V::::E::::::::::::
Hmu2874         :T:::H:::K::::H::D::::FE:::::::E:::::ES::AT:::M:::::::::::D:

consensus       FPPCMKHLLDQVQKGEHLEHHSRFAIASFLASIGMTTDEIVDLFQVNPGFGEEATRYQTD
#oth            .....22...1..1.1..1..1...112..321.12..1..1111........1....1.
VNG2254         :::::::::::::R:D::P::A::::T:::SNV:LS::::::IYE::::::::M::::::
Hut2352         :::::TA:::::::::::P:::::::T::::::::A::D::::YE::::::::M::::::
rrnAC2844       ::::::S::::::::::::::::::::T::VG::::::::::::::::::::::::::V:
Hmu2874         :::::Q::::A::::::::::::::L:A::T::::::::::E::::::::::::::::V:

consensus       HIRGDTSPTEYSTPSCATMQSYGDCVNMDDLCE---AISHPLSYYEAKLDDTDDEELADW
#oth            ..1..1.....12.1.1..11..1.112..1.1111111..12...31.112.11123..
VNG2254         ::Q::S:::::TA::::::KA::N:::P::::D:::::N:::::::V::::G::DD::::
Hut2352         ::::::::::::P::::::::::::::::::::::::::::::::::::E:A:E::MI::
rrnAC2844       ::::::::::::::A:S::::::::::::::::::::::::MG:::Q::::::E:::V::
Hmu2874         :::::::::::::::::::::::::KGK::I::DEINE::::N:::HR::E:::::VE::

consensus       RERE-DDDEADA
#oth            .12.12212321
VNG2254         :D::::::SP:-
Hut2352         :::::EA::---
rrnAC2844       ::D::GEE::::
Hmu2874         ::N:A:::DGE: