4 genomes BUD1978 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0077 rrnAC1542 - - Hmu2394 Hut1688 - - -

Pairwise sequence scores
Consensus score	2933	Hut1688	VNG0077	Hmu2394	rrnAC1542
523	Hut1688	1180	240	384	406
1315	VNG0077	240	1911	993	1035
2442	Hmu2394	384	993	3446	2166
2476	rrnAC1542	406	1035	2166	4018

557 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
Hut1688         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0077         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2394         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1542       MNTRRIAHKGIATIQIVSARRDAILIAGRGPGSRLRLLTLRCRKIGRSPAFGGMTLADAG

consensus       ----------------------MALIDDDGNLFGRVNVIDALVVLLVLAVVVAGAALVLG
#oth            11111111111111111111112322112.221131112121221212221111221131
Hut1688         :::::::::::::::::::::::DV::EQ:R:::T::::::::::V::ST::::::::V:
VNG0077         ::::::::::::::::::::::--MAN:::------------------------------
Hmu2394         :::::::::::::::::::::::Q::::E::V::::::::G:::::::::::::VS::F:
rrnAC1542       QSDNETPKPLGRNDYRMADSRSS::L:E::::::L:::V:::AA:::I:::::::::::-

consensus       QNEPAEPD--TTNVTLDLG-QP-Y-V-E---GD-YSPG--S-LTITD--L-PQD-QT-V-
#oth            232232112211111111121121212122211211112212111112212111211212
Hut1688         :ES::::-::---------:--:-:-:-:::--:----::-:-----::-:---:--:-:
VNG0077         --------::---------:--:-:-:-:::--:----::-:-----::-:---:--:-:
Hmu2394         N::QS:::LP:::::::::P::D:V:A:MNQ::S::::DN:N:::::IY:S:::D::H:T
rrnAC1542       :P::EP::PN:::::::::T::S:I:T:ITE::T::::GD:K:::::VH:T:::N::R:I

consensus       -RA--Q--PD---D-LTYADAPLRLGRPLDIATSRYEVSGQIRAVGGNASLDRETTTVVL
#oth            211221221111212311222221111312111211212121122123312332212122
Hut1688         :--::-::--:::-:---------------------------------------------
VNG0077         :--::-::--:::-:M:::::::::::S:::::N::Q:::A::S::A::::PTD::D:L:
Hmu2394         V::EI:DR::DNS:GP::::GL:::::T::::::::::::::::I::GT::::::::::V
rrnAC1542       L::TL:GP::::G:S:::VN::A::::::T::::::::D::::::::DN:FTQ:D:::::

consensus       RDTLPAADARAVTPGDEIRLAGRTVATV-DVAAY-T--S---TV-VEAEL-T--QR--RR
#oth            322322321232131122123121211221111121221222112111112122112211
Hut1688         ----------------------------:-----:-::-:::--:-----:-::--::--
VNG0077         ETG:::V::DE::V::QL:IG:Q::::::-----:-::-:::--:-----:-::--::--
Hmu2394         Q::V::T::::I:T::::::::::I:::T:::::P:NK:AQR::Y:::::E:YA::GE::
rrnAC1542       :::MAT:E::D:::::::::S::::::IE:::::T:EN:TEQ::F:::::D:HR::SD::

consensus       FG-TQ-RRGQTVTLPA--YT-DGR-E-V--GL-----DVL-E-TVD-ETA-RIA-GDI-T
#oth            112112111111111122112111212122112222211121211121112111211121
Hut1688         --:--:----------::--:---:-:-::--:::::---:-:---:---:---:---:-
VNG0077         --:--:----------::--:---:-:-::--:::::---:-:---:---:---:---:-
Hmu2394         ::N::L::::::::::SE::I:::L:R:GG::DRGEV:::V:S:::V:::N:::E:::A:
rrnAC1542       ::G::I::::::::::ED::F:::I:K:DS::QPTTT:::L:T:::A:::G:::A:::T:

consensus       V-G-E-AEVRTITTYATRNPDQARVLVGITLATLSDADRQQFGSTAVQRGNNIEIATESY
#oth            121212111221122.132.2232.21112121222333221122312111233231221
Hut1688         -:-:-:---:E::IS:QTP:V:PY:AAA:-------------------------------
VNG0077         -:-:-:---E::NAH:::D:N:H:::::L::::I::G:TTR::V:P:R:::TLSL::DE:
Hmu2394         :A:H:T:::QRV:::::G:::K:H:F:::::Q::::DQY::::::H::::::V::E::::
rrnAC1542       :G:Y:A:::::V:::::Q:::RK:::::LS::::EN:G::::::V::::::::T:S::::

consensus       ALSGRIRRVGALEPRGTLTNRTVTLRMTDIREDMADTIDAGMTEASDGETIARVTRVDIE
#oth            212131311121112.1222111113222212132222331111321121111.211222
Hut1688         -------------:E:SV----------------------------::SSVVA:HNKS:R
VNG0077         E:D:::Q:::T:::P::P:I:::::EISEV:::F:E:FH:::::RA:D:::::::N::V:
Hmu2394         ::::P::::::::E::::S::::::::::::::TT:A::V::::H:G:T:V::::::::D
rrnAC1542       ::::T:E::::::::::::::::::W:::::A::::::EP::::::G:::::::S::NT:

consensus       PSTIITTGDNGSVNVVDHPINRDVTLTTELRVRE----ATSGVRFKGESLQQGSTVVLDL
#oth            .2121212.2.11122...31.1..2112.2.1.1111311122.1222121111.1211
Hut1688         :T:VAVRA:::TLHER:::L::T::MAVT:S:S:VPDDGVTAY::ND:P:EI:RS:TF:F
VNG0077         :::L:::::D::::::::::::::::::D:Q:::::::::T:TT:::R::::::::::::
Hmu2394         :AV::A:D:S:::::::::FL:::::::::::::::::T::::::::DTIR:D:::::::
rrnAC1542       ::V::::::::T::IA:::YL::::I::::::::::::S::::Q::S::::::::::IN:

consensus       GTITIEATVVSAGA---
#oth            .1211221.21323111
Hut1688         :RVSVNG::T:FASEPG
VNG0077         ::T:::::::N:D::::
Hmu2394         ::::VRTE:A:I:G:::
rrnAC1542       :::::::::::V:L:::