4 genomes BUD1996 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_2059 Hbo2955 Hmu2655 Hut2860 - - -

Pairwise sequence scores
Consensus score	2343	Hut2860	HVO_2059	Hbo2955	Hmu2655
1824	Hut2860	2353	1577	1654	1615
1951	HVO_2059	1577	2373	1775	1775
2072	Hbo2955	1654	1775	2317	1973
2059	Hmu2655	1615	1775	1973	2352

311 symbols
consensus       MRILVTGGAGFIGSNFVHYLLDAH-DDEVVTLDALTYAGSKDNLDGVLDNPRHEFVEGDI
#oth            .11..............11111331.11111........112..2.2..3.111.1....
Hut2860         ::V::::::::::::::::::::T::H:I:V::::::::D:S::::A::S::C:::::::
HVO_2059        :DV::::::::::::::R::::NS:::S::::::::::::R:::A:Y::H:N:R::::::
Hbo2955         :::::::::::::::::::VIEQY:::::::::::::::::E::E::::::::::I::::
Hmu2655         ::::::::::::::::::HV::E:E::::I:::::::::::::::::::D::::::::::

consensus       RDRELVRDLVADVDAIVNFAAESHVDRSIEGAKPFVSTNVQGTQTLLDAARDADIDRFLQ
#oth            ..31..31111.2121.............2122...2...1.........3221.1..1.
Hut2860         ::Q:::EERT:::E:::::::::::::::HEDA:::::::G::::::::::TH::E::V:
HVO_2059        ::::::D:::::A:V::::::::::::::G::E:::::::::::::::::L:::::::::
Hbo2955         ::E:::::::::::TV::::::::::::::::::::E:::::::::::::K:SG:E::::
Hmu2655         ::HD::T:::D:I::::::::::::::::::S::::T:::::::::::::NE::::::::

consensus       ISTDEVYGQILDGKFSEDDPLNPRNPYAATKAGADHLARSFRTTHDLPVLITRTCNNFGP
#oth            ........1.21.1.1.1.2.2.....1....1..1.13.132.1.1.1....11..1..
Hut2860         ::::::::::AE:T:::::K:D::::::::::::::::M:YHV:Y:V::::::SS::Y::
HVO_2059        ::::::::E:H::::T:::::A:::::S:::::::L:V::Y:E:::::T:::::::::::
Hbo2955         :::::::::::::::::::::::::::S::::S:::::K::E::::::::::::::::::
Hmu2655         :::::::::::::::::N:S:::::::::::::::L::Q::Q::::::::::::::::::

consensus       RQHPEKLIPKFIQRAAEGESLPVYGDGSNVREWIYVEDNCRALDRVLREGDIGEIYNIGS
#oth            ...1.......121.22.12..1....2.....1.11...1.1131.11.12.11..1..
Hut2860         :::R:::::::LT:::::::::L::::T:::::T::R:::::IE:::AD:EP:::::V::
HVO_2059        ::::::::::::::::N::T::::::::::::::::::::A:::V:::::::::V:::::
Hbo2955         ::::::::::::KN:S::K::::::::::::::::A::::::::T:::::E:::::::::
Hmu2655         :::::::::::::N:DS::E:::::::L::::::::::::::::II:::::V:DV:::::

consensus       GAELTNLEVTEAILDAVDADEDLIEFVEDRAGHDQRYALDTEKIEALGWEPEWSFEEGLE
#oth            22.12.1.11.2..1..112221.1..1..1.......1112.112.1.11111..1...
Hut2860         :E::P:V::A:R::E::::P:S::::::::P::::::::::A:::E:W::A:::::::::
HVO_2059        :V::S:::T::K::E::GGS::Q:::::::::::::::I:AT:TK:::::::::::D:::
Hbo2955         H::K:::::::::::::G::KA:::::::::::::::::E:::::S:::::AYT::::::
Hmu2655         Y::K::::::::::::::::D:::T::D:::::::::::E:::::::::K::YT::::::

consensus       ETVRYYLN---
#oth            21.3...3211
Hut2860         :::::::DE::
HVO_2059        AC:D:::GDDE
Hbo2955         :::E:::E:::
Hmu2655         R::N:::::::