4 genomes BUD1997 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_2057 Hbo2958 Hmu2659 Hut2857 - - -

Pairwise sequence scores
Consensus score	2655	Hut2857	Hmu2659	HVO_2057	Hbo2958
2163	Hut2857	2670	1230	2014	2005
1687	Hmu2659	1230	1882	1507	1619
2342	HVO_2057	2014	1507	2654	2282
2447	Hbo2958	2005	1619	2282	2667

357 symbols
consensus       MKGVLLSGGTGSRLRPITHTGPKQLVPVANKPVLEYAVEDLKEAGITEIGVILGHKGREA
#oth            111111211111111111111111121111111111121111211112111211111113
Hut2857         ::::::A::::::::::::::::::L::::::::::::::::D::::D:::V::::::::
Hmu2659         ------------------------------------------------------------
HVO_2057        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::E
Hbo2958         :::::::::::::::::::::::::::::::::::::I:::::::::::::::::::::D

consensus       IQELLGDGSDYGVDITYIVQGNPLGLAHAAGCARDFVGDDDFVMYLGDNILKSGVTDLVE
#oth            1121111113111211111111111111111112111111111.........2.12....
Hut2857         :::::::::E::::::::::::::::::::::::::::::::::::::::::Q:IE::::
Hmu2659         -------------------------------------------:::::::::::::::::
HVO_2057        ::N::::::::::E:::::::::::::::::::K::::::::::::::::::E::V::::
Hbo2958         :::::::::K::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       SFEAGDYGAGIALQEVDNPQAFGIADVDDQGNVTRLIEKPDDPPTNLALIGMYVFSPAVF
#oth            ..11.11.........21.12...112.1111..3.1...11..111....1....111.
Hut2857         ::Q::E::::::::::Q::SE::::ET:AD:A::::V:::A:::S:R::::I::::ND::
Hmu2659         :::::::::::::::::D::::::T:I:::::::K::::::E:::D::::::::::::I:
HVO_2057        :::S::F:::::::::E:::Q:::::::::::::Q::::::E::::::::::::::::::
Hbo2958         :::S::::::::::::::::::::::::::Q:::E:::::::::::::::::::::::::

consensus       DAIEELEPSWRGELEITDAIQRLLEDGYEIDSHVVEGWWKDTGKPEDILEANRLVLEDKA
#oth            .1.22................3..11.22......1.......1.1...1..1...1113
Hut2857         :V:::::::::::::::::::D:::E:NP::::::::::::::R:Q:::D::::::::V:
Hmu2659         :::T::::::::::::::::::::D::::::::::T::::::::::::::::::::K::E
HVO_2057        ::::Q::::::::::::::::S::::::A:::::::::::::::::::::::Q::::::S
Hbo2958         :::DD::::::::::::::::H:::::H:::::::T:::::::::::::::::::::E:T

consensus       LNRAGTIEDDAETDGRIELAPSARIEAGAVVRGPVSIAENTTIKSGTYVGPYTSIGANST
#oth            1333.11111.112.111..2..31.11..1...1..12111.12.........1.1111
Hut2857         DD:::E:ST:::VT::VD::::::V:::::I::::::EAG:::GP:::::::::::PDCE
Hmu2659         ::IS:::::G:::::Q::::D::I:::D::::::::::::::::D:::::::::::::::
HVO_2057        :KKR::VS:::TV:::::::E::T::D:::::::::::DGAV::::::::::::V:P:::
Hbo2958         :ETE::V::G:::H::V::::::V::D:::::::A:::::::::::::::::::::::::

consensus       LADVHIENSVVIGDSEITASGRIVDSLLGRNANIESAADELPEGRRLVVGENSQLKL
#oth            .112.1..1.11.1.2112211.....1.131121..1131.1.....1....1...
Hut2857         :::::V::T:LV:E::V:SAET:::::I:::TR:G:::::R:A::::::::::N:::
Hmu2659         :E:I:::::::::::D:::D::::::::::K::V::::EL::::::::I::::::::
HVO_2057        :EG::::::::::E:S:NT::::::::::KG:::G::D:F:::::::::::::::::
Hbo2958         :::T::::::::::::::::::::::::::S::L:::DEH:::::::::::::::::