[P] (ECM27) COG0530 Ca2+/Na+ antiporter 4 genomes BUD2008 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0380 - HVO_0714 Hbo0822 - - hla2421 - -

Pairwise sequence scores
Consensus score	2257	VNG0380	hla2421	Hbo0822	HVO_0714
1523	VNG0380	2259	1240	1236	1115
1559	hla2421	1240	2208	1263	1244
1808	Hbo0822	1236	1263	2246	1505
1697	HVO_0714	1115	1244	1505	2287

323 symbols
consensus       -MADSLL-STDGALLVAGIVALYAGAELLVRAASRLAIGHGIRAATVGVTVVAFATTAPE
#oth            221323.2122321.22.221..2...2..31..2..123.11.12....1......1..
VNG0380         ::::::::-VN:GI:::::LL::V::::::S:::A::LS:::K:::::::::::::::::
hla2421         VLLG:P::-:ELL::AG:AAL:::::::::KG::D::LAV:LK:S:::::::::::::::
Hbo0822         :::STV:L:::M:::LV:V::::::::F:::::::::::F:::::V::::::::::::::
HVO_0714        MS:LAT:I:F:T:::::::::::L:::A::EG:::::::L:L:::I::::I::::::T::

consensus       LFVSLLGGITYSTDLGLGAIVGSNIANIGLVLGISALIRPLNVDQTVLRRHVPFMIAAAL
#oth            .1.2211132212221..1..............31..21.1211322131.2...31..2
VNG0380         ::::TV::::AGDSIA::N::::::::::::::TA::L::MD::K:L:YH:G:::L::::
hla2421         :::::::AV:V:::T::::::::::::::::::V::::::::IS:::FE::I:::VL:::
Hbo0822         :A:V::S:FS:::N:::::::::::::::::::L:::V::::::ES::I::::::F:::G
HVO_0714        :::AV:S:LG::S:::::::::::::::::::::::::E:MG:STAT::::::::::::V

consensus       LLVGLGMDGRIGAVDGVVLLAVLAAFTAYLLRRARQARADAIAADDVDMDDDAEVGA--R
#oth            2..2.12..31112..12..12.11..212111112333121321221221233232111
VNG0380         A::::SL::TL::L:::A:::L::V::::IY:H:Q:DDD:VSLP:::::::::TAT::::
hla2421         ::::::W::Q:::::::L:::::V::::VV:::VQ:TQSGIS::ERAE:PEARV---:::
Hbo0822         :::L::::::::TF::::::::::V::S:::Y:V:AS:P:::PVE:::V:::SS::V:::
HVO_0714        V::A:::::NLS::::G:::LI:V:::G:::Y:::S:T::::G::EI:IE:ED::S:QFK

consensus       DAVALVGGILLLLVGSRWLIQGGQGLLEAFGFGDRFIGLTVLAFGTSLPELAASVISAAR
#oth            .2131221121.22..21.12..111.322..122......1.1...1....1.111.31
VNG0380         :Y:V:::A:::::G:::A::T::R:V:ME:::S:L::::::I:::::V::::T::V::L:
hla2421         ::A:V::::VA:V:::S::VD:::S::S:A::S:I::::::::L::::::::::::A:I:
Hbo0822         :::I:LA:LG:::L:::::::::::V:K:Y:::E::::::::::::::::::::IV:::K
HVO_0714        :V:Y:AL:L:::F:::N:::::::::::S::::P::::::::::::::::::::::::V:

consensus       GEAEFSIGNVVGSNIYNILAVIGILAILVPINVPPSTLALDFPALLVFTVLVVALMARGR
#oth            1.121.1..........11..1.11.121.13.222122111.1112..222211.2211
VNG0380         D::D:::::::::::::V::::::V::::::T:TKG:::FEL:VM:G::::ALGM::V:D
hla2421         ::::::V:::::::::::::::::V:VVT::S:A::VRGFE:::::A::A:L:G::Y::D
Hbo0822         :::Q:::::::::::::::::::V::V:::VG::AE:::::::::V::::V::::::Y::
HVO_0714        ::S:L::::::::::::VV::L:::::M::V::::::IS::::::::::FG:I:::L:N:

consensus       RISRVDGAVLVVGYLGFFYLLLP
#oth            211.21.21.111.22.121111
VNG0380         ::T::E::::IGS:G::V:F:V:
hla2421         :::::::S::::::VL:V:::::
Hbo0822         TV::A:::::::::::::S:::-
HVO_0714        DV::L::GI::::::V::W:I::