4 genomes BUD2030 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC3038 HVO_2904 Hbo2683 - - hla1237 - -

Pairwise sequence scores
Consensus score	2248	rrnAC3038	hla1237	HVO_2904	Hbo2683
1264	rrnAC3038	2342	828	847	916
1281	hla1237	828	2388	861	778
1585	HVO_2904	847	861	2248	1197
1514	Hbo2683	916	778	1197	2268

331 symbols
consensus       ------R--MAVVGVAVLAFYLAAAAASALALLILWRLRPDLLTAALFVLGVAVVLGYLS
#oth            122222122111..122121.23111321211231.221111221222222212221112
rrnAC3038       :MAVTR:LL:::::LFS:LV:FT::YVGY:L::PV:DS::SP:M:::::::T:IA::VVN
hla1237         MSRLAF:AAA::::::L::V::::::FV:D:::F::AT::::PVLLALLAV:::GSA:::
HVO_2904        ::::::-:::V::::V::::::SLS:L::F:VVT:::::::P::::VVGVA:::::::::
Hbo2683         ::::::-:::VF:::::FV::ALL:Y::Y:::S:::::QF::T::V:::::FTL:F:::G

consensus       YRAGTARLLSQLDARELPRARAPDAHHRLDALAARMDLD-PPTLLLARLAAPNAFALGDG
#oth            2131.111121.2132111112.321122.2.122.21112.2.3113232...1.2112
rrnAC3038       :W:A::Q:KRS:N:V::::::::E:Y::::::VDQ:NVE:T::::::E:PV:::::I:G:
hla1237         :WI:::QV:AS:EGDR:::E::::L:::I:::::::AV::R:A:YVTDAR::::::V:G:
HVO_2904        F:F::V:::::::::DMSP:ES:SV:RLR:R::E::::::::::K:::F:::::M::-:P
Hbo2683         L:V:::::::::::Q::::E:V:G:Y:V::G:::E::::E::R:MV:S:ST::::::-:T

consensus       MGRNTVVVDRSLFRILDADEFEALLAHELAHLERKDGLVQTLAASIGQTVVGLAYLAVAP
#oth            2.2322.2.22...1.112.2.111........12.2.112213133111.12321323.
rrnAC3038       T:--:I::::R:::L:S:A:::G::::::::::TR:A::::V:Y:FV::L:::IG::LF:
hla1237         S:GGAL:M::::::::S:R:V::IV::::::::TN:::ALAM:DG::RA:::FTTVLAL:
HVO_2904        :::DV::L:A::::L:::::::::::::::::::::::::S:V::VL:::::VG::F:S:
Hbo2683         :::::::::TV::::::R::L:G:::::::::::::S::::::F:TI::::N:::VV:::

consensus       AAFLTTGLALSSAWIRGRPGSWSETLAGRARRRLDQGVALAGFVL-TLLARSRSRKREFA
#oth            332122.2.222.13..1.211222221132221322232311221.112123..1..2.
rrnAC3038       IVV::G:I:R:L:LL::D:S:::RSWL:::Q:YSL:V::GL::AV::::LLGY::R::L:
hla1237         :LLALS:::AA:::::::::DR:GPF:-WLH:A:TN:L-F:::::A::::::::::::::
HVO_2904        VT:::::V::G:::M:::::::T::::::V:L:::EF:G:F::G:::VFV::Q:::::::
Hbo2683         F:::V::::::T::V::D:T::P:::P::I:H::E::AS:VMG:M::::::AH:::::Y:

consensus       ADDRAAEVTGRPIALARALRKIERAARPDHG-LSPLWVYGEVENE----LSRLLSTHPSI
#oth            ..2..111.13.31..1..211.1.1313312121122221212122112211.....21
rrnAC3038       :::::V:I::N:VG:::::A:::Q:ST::P:L:RQVY:HS:AD:::::::::::::::P:
hla1237         ::::::::::D:::::::::R:::::E:SWP:FT::ST:KRT::P::::AE:W:::::::
HVO_2904        ::A::::::DK:M:::S::::L::::::Q::::::::::::::V:DS::V:D:::::::T
Hbo2683         ::E:::A:::::L::::::E:L:::SSAEF:I:::::IR::::S:EERR:RD::::::RT

consensus       DERVERLRDRAA-QNRTRI----SER---RR
#oth            11.12..222.32323112111123122211
rrnAC3038       :::MQ::Q:::QYG:F:KS:::::::PSS::
hla1237         E:::::::R:::A:ES::RIPIGPS:GGR::
HVO_2904        :::::::AAM:D:ESM:::::::EV::::--
Hbo2683         ED::K::::H:E:S::V:::::::--:::--