[R] (-) COG2402 Predicted nucleic acid-binding protein, contains PIN domain 4 genomes BUD2054 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0072 - HVO_A0188 - - Hut1519 Hut2254 hla2249 - -

Pairwise sequence scores
Consensus score	1121	HVO_A0188	VNG0072	hla2249	Hut1519	Hut2254
662	HVO_A0188	1118	551	465	295	278
710	VNG0072	551	1089	562	273	311
663	hla2249	465	562	1116	284	258
549	Hut1519	295	273	284	1180	564
549	Hut2254	278	311	258	564	1154

161 symbols
consensus       ---------MPVFVDTGVFYAHHDTDAARHDAAAAALDAIG-DGE--FGQLYTSDYVLDE
#oth            11122221122111...111.31122.4..1213212212312212211221122.211.
HVO_A0188       ::::::::::S::::::::F:::::::D:::Q:VS:F:DLF:::::::::P::N::::::
VNG0072         ::::::::::T:L:::::L::D::::::::E:::G::::VY:::::::::P:V:::LY::
hla2249         ::::::::::S::::::::::::::::S::E:G::::N:VLRSA:::Y:HVM::::IY::
Hut1519         VSRTVDPGAI:L:I:::A:::RFVGT:Q:::R:T:VFE::::T::VAYRP::::T:::::
Hut2254         :::MSGAGAT:L:::::A:F:SFVSN:P:::Q:R:VM::::::DRLH:RP:::TN:::S:

consensus       LVTLTLARTRDHDAADAAGRRIRGEDPYP--IRMLHPDAADFDAACEAFERYDDHQLSFT
#oth            31..32222322121434231212222213342312244231222234231121121..1
HVO_A0188       T::::R:::DSFE:::TVAG::L::E:F:NVF::I:VEPD:VR:SL:TLR::E::D::::
VNG0072         A:::A:::SSSF:V:QRL:::L::A::::ETY:::DVTT:V::D:VGV:::L::Q:::::
hla2249         S::::HR::::I::GLEI:::::::-G::SA:EL::SSETL::R:VTIQ:T:AK::::::
Hut1519         :A::I:SH-::::::T::LE:V:ES-:--::TTVIQ:GR::::R:::E:A:::::EI:::
Hut2254         :A::V:RK-AG:ER:S:TLSW::DS:A--::VTI:::::TT:G:V:A::D::::Q:I::V

consensus       DAMTVALARRHDIDAVLSFDDD-FDGLVDRLVPADRDE-D-
#oth            .12222132411114.12..2.1.11113222.33444321
HVO_A0188       ::TI:::CESRG::::::::T:::::::::IE:GH:SV:-:
VNG0072         ::T::::M::::V:G::::::::::::::::D::AVV-:-:
hla2249         ::::::HVEH::::C:::::::::::V:T::::ETLFSR::
Hut1519         :H:SGV::DDR::EH:FT::P:H:RT:GFTA::D:TG:GL:
Hut2254         :HA:AT:::E::VEY:FA::T:::RT:GLS:::::I:MP:V